2.22 Acres Zoned C-1 - Prime Commercial Opportunity in Growing Area Rare opportunity to own 2.22 acres of commercially zoned (C-1) property in a rapidly expanding area. This parcel is ideally positioned directly in front of a newly developed townhome community, offering excellent exposure to a growing residential population. With new businesses continuing to move into the area, this property is perfectly suited for a variety of commercial uses including retail, office, or service-based development. This an ideal opportunity for investors, developers, or business owners. Secure your place in this high-growth corridor while opportunities like this are still available. Seller also owns 903 Moody Rd.
Located in the heart of Palatka's vibrant and growing downtown district, this highly visible commercial building sits at the corner of the busiest intersection downtown, with approximately 20,000 vehicles passing daily -- offering exceptional exposure and branding potential. This well-maintained property features five fully leased units, providing stable, diversified rental income and strong occupancy performance. Each unit benefits from Downtown Business zoning, supporting a wide range of commercial uses and appealing to a variety of retail, office, and service tenants. This asset presents an outstanding opportunity for investors seeking a turn-key, income-producing property in a central, walkable, and increasingly desirable Florida downtown market.
Well-located commercial property consisting primarily of professional office and medical space. Positioned in the heart of town with immediate proximity to the local hospital and college, this property benefits from strong visibility and consistent tenant demand. The building is configured to accommodate multiple office and medical users, making it ideal for investors or owner-occupants seeking a centrally located asset in a high-traffic area. Convenient access, ample parking, and a highly desirable location set this property apart.
Turnkey daycare facility on a prime corner lot. Exceptional opportunity to acquire a daycare facility in a proven, established location. Situated on .69-acre fully fenced corner lot, this property offers great visibility with approximately 206 ft of frontage on St. Johns Ave & 150 ft on North 13th St. The main building features over 5,900 sq ft of heated & cooled space, complemented by a detached corner building with more than 1,800 sq ft, also heated & cooled. The secondary building offers exellent flexibiity & could possibly be separately leased for additional income. This property also presents a strong potential for office or retail use. Ideally located near the growing & vibrant downtown Palatka area, this site combines accessibility & versatility.
Courtesy: MIHARA & ASSOCIATES INC.
813-960-2300
This 12-unit, mobile home park sits on 2.38 acres in Palatka, FL and offers investors an established income-producing asset in a high-demand affordable housing market. The park operates on well water and septic, helping keep operating costs manageable. With all rentable units currently occupied, the property delivers immediate cash flow and long-term investment potential. The expansive acreage provides flexibility for future opportunities, subject to zoning and buyer verification. A compelling option for investors seeking stable returns in North Florida.
Courtesy: 3 DOT REALTY LLC
386-235-0670
Introducing a strong-income–producing multi-suite office building in the core of Palatka’s business district. Positioned just off St. Johns Avenue, 216 S 6th Street offers investors reliable cash flow, affordable operating costs, and proven tenant demand in a growing commercial corridor. This 9-suite professional office building features a diverse mix of small businesses and service providers, creating stable occupancy and minimized tenant-turnover risk. The building’s configuration supports a wide range of office uses, including administrative, professional services, consulting, nonprofit, medical-adjacent, and remote-work spaces.
GREAT Cleared - Fenced 3.6 acre lot on busy Hwy 17 in Palatka. OWNER FINANCING !! or LEASE - Owner wants a cash flow......not pay off. Great lot for RV/Auto/Boat Sales or Storage. Great lot for sale of Storage Sheds. Great lot for Mobile Home Sales. Lot is Cleared of all trees, grass is cut, Lot is fenced and ready for use. 234' Ft on Hwy 17 - over 9,000 cars/day drive by.
Opportunity to own commercial property with great highway frontage. Cleared and ready for new business adventure. Many possibilities and plenty of great exposure.
Prime Commercial Opportunity: 4.7 Acres on SR-20 High Visibility Fully Accessible Development Ready Unlock the potential of this exceptional 4.7-acre commercial parcel situated on the bustling SR-20 corridor. Boasting over 500 feet of direct highway frontage, this property offers unparalleled exposure for your business in a high-growth area. Property Highlights Optimal Zoning: Zoned C-3 (General Commercial), allowing for a wide range of intensive retail, service, and professional uses. Strategic Location: Positioned on a 4-lane highway with a high traffic count of 13,264 AADT (Annual Average Daily Traffic), ensuring constant brand visibility. Ready to Build: The land is high and dry, mostly cleared, and level—significantly reducing your site preparation costs and timelines. Existing Infrastructure: Save on permitting and construction with an established curb cut already in place, providing immediate, easy access to the site. Why This Location? Whether you are looking to develop a retail center, professional office complex, or a high-traffic service facility, this 4.7-acre site provides the scale and accessibility required for a flagship location. The combination of extensive frontage and "shovel-ready" characteristics makes this one of the most attractive commercial opportunities currently on the market. Don't miss the chance to secure a footprint on one of the region's primary arteries.
Courtesy: PEPINE REALTY
352-226-8474
HUGE PRICE IMPROVEMENT! FANTASTIC opportunity to own almost 4,000 sq ft of office space in PRIME location in the Historic Downtown Palatka Business District! This property has 3 separate spaces with their own entry and bathrooms, making for a very flexible situation for the next owner(s). The first office space downstairs yields 2,580 square feet and the second office space contains 1,140-square feet, while the third office space is 273 feet. Second office space could easily be turned into an apartment if desired as it's features has a beautiful staircase that takes you to the second floor after entering from the sidewalk into a foyer area. Lots of opportunity exists with this property that sits smack in the middle of the action in Downtown Palatka! Don't miss out on this ideal situation.
Prime medical office space in a premier location! Currently used as Putnam Diagnostic Imaging Center, this 6,420 sq ft building is located in a well-established medical district, just SW of HCA Florida Putnam Hospital. The layout includes a lobby/receptionist area, exam room, physician offices, break room, nurses' station, MRI room, CT scan room, X-ray room, bone density room, mammography room, two dressing rooms, five bathrooms, consultation room, and storage for equipment or supplies. Features public water/sewer, commercial grade carpet & vinyl flooring, plus a wet fire sprinkler system. Situated on 1.02 +/- acres with 150 ft of road frontage. Zoned C-1A (Commercial, Neighborhood District), allowing retail, medical, and professional office uses. An ideal location for medical professionals seeking close proximity to a major healthcare facility.
Excellent opportunity! 1930 home zoned C1 Commercial Light with 3 bedrooms, 2 baths, and unfinished spaces. Much of the restoration is complete— just needs your finishing touches. Great visibility on a busy street—ideal for office, studio, or live/work setup
Courtesy: HOME PRIME REALTY LLC
813-497-4441
Unlock the potential of this prime commercial opportunity in the heart of Palatka! Positioned directly on Reid Street (SR-100) with outstanding visibility and constant traffic flow, this C-2 zoned property is ready for your business vision. Featuring an 877 sq ft warehouse/flex building on a 0.47-acre lot, this site is ideal for contractors, trades, logistics, storage, distribution, or any business in need of a highly accessible commercial location. The building offers private office space, restroom, 220-volt electrical service, public water, septic, aluminum-frame windows, security lighting, and a convenient grade-level bay door for easy loading. The expansive lot provides excellent parking, outdoor storage capacity, and room to grow. Whether you’re expanding your business, relocating, or searching for an investment with strong commercial zoning, this property delivers flexibility, exposure, and endless potential. The property is vacant and easy to show — bring your vision and make it happen!
Fantastic commercial opportunity in the City of Palatka! This 932 sq ft property is zoned C-2, offering excellent flexibility for a wide range of business uses. The interior has already been fully gutted, providing a clean slate that's ready for your custom build-out and vision. Located just off one of Palatka's main commercial corridors, this space offers close proximity to other retail shops, restaurants, and established businesses, making it an ideal spot for strong visibility and steady foot traffic. Perfect for a variety of uses, including Retail shops or specialty boutiques, professional offices (insurance, real estate, consulting, etc.), personal services, salons, or wellness concepts, medical, dental, or therapy practices, cafés, bakeries, or grab-and-go eateries, creative studios or showrooms, and many additional uses permitted under C-2 zoning. With its central location, accessibility, and blank-canvas layout, this property is ready for an investor or business owner looking to create a standout space in a growing commercial area. Come see today and make your dream of business owning come true!
Turnkey Medical or Professional Office Space – Prime Location in Palatka, FL Presenting 200 Mission Rd, a move-in-ready medical office building located in the heart of Palatka. Spanning 2,903 sq ft with an additional 2,091 sq ft detached building, this versatile property is ideal for healthcare providers, wellness centers, or general office use. Property Highlights: Functional Medical Layout: Includes multiple exam rooms, a large reception area, physician’s office, break room, file/storage space, and ADA-compliant restrooms. Additional Structure: A secondary building offers flexible space for expansion, specialty services, or separate tenant occupancy. Ample Parking: Spacious lot with over 2 acres of land provides generous on-site parking and room for future development. High Visibility & Accessibility: Located on a well-traveled road with convenient access to downtown Palatka, major highways, and local amenities. Zoned for Office/Medical Use.
Rare Opportunity! This is the only privately owned multi acre parcel around the Palatka Golf Club, which was designed by Donald Ross in 1925. Two parcels for a total of 15.73 +/- acres, with frontage on the 11th, 12th, and 14th greens. This property has a very unique terrain and is currently zoned R-1AA. Great potential for development of multi-family with rezoning. Approximately 330 ft of frontage on Lundy Rd.
Great location for you to build your business! Located on State Rd 20 (Crill Ave), which is a heavily traveled 4-lane highway for excellent exposure. Close proximity to the hospital and medical facilities. Property is zoned C-1 for multiple uses. This consists of 3 parcels totaling 5.92 acres (+/-). Approximately 360'' of highway frontage. Only a survey can determine the exact parcel size. Parcel # 10-10-26-2100-0010-0050 (.45) 6679 Crill Ave, Palaka, FL Parcel # 10-10-26-2100-0010-0010 (1.49 acres) 6677 Crill Ave, Palatka, FL Parcel # 10-10-26-0000-0390-0010 (3.98 acres) TBD Crill Ave, Palatka, FL
Multi-Use Property with a Fresh New Metal Roof! Sellers just installed a brand-new metal roof 12/25, giving this versatile 2,232 sq ft concrete block building incredible value and worry-free ownership from day one! Featuring a spacious sanctuary plus full living quarters, this property is perfect for a live/work lifestyle, a one-of-a-kind residential conversion, creative studio, or continued use as a church. *some photo's have the old roof* The open, light-filled main area is ideal for gatherings or transforming into a dramatic great room. The attached living quarters provide comfort and convenience while you make the space uniquely yours. If sold to another congregation, church furnishings and musical instruments can convey, making this a turnkey ministry opportunity. Agricultural zoning offers room for parking, gardening, or future expansion. A standout property full of potential — come explore how your vision can thrive here!**some photos have the old roof**
Courtesy: GREAT EXPECTATIONS REALTY
904-823-3456
Welcome to 1321 St Johns Avenue—an exciting commercial opportunity in the heart of Palatka, offering endless potential for your business vision. This concrete and brick building on slab, has recently received a new roof (2025) upgrade on the front office portion of the building and is ready for your fresh ideas and renovation to make it perfect for your business. Boasting 2,110 sq ft of open space and situated on two parcels totaling 0.23 acres, the property features large windows front-facing St Johns Ave—perfect for high visibility and attracting walk-in traffic. The corner lot location just one block from Reid St/US-17 provides exceptional exposure and convenient access to commercial corridors and downtown making it an ideal site for a storefront, office, studio, or specialty retail. Zoned C-2 in Putnam County, this property supports a wide variety of commercial uses. With one bathroom in place and a highly adaptable layout, you can create whatever fits best for you. Cash offers preferred. Seize this chance to establish or expand your business in a prime Palatka location. The listing includes two parcels: #42-10-27-6850-2530-0051 & #42-10-27-6850-2530-0050
Courtesy: GREAT EXPECTATIONS REALTY
904-823-3456
High-Visibility Redevelopment Opportunity – 1.61 Acres in Growing Palatka Market Presenting a premier commercial offering in Palatka, Florida—spanning 1.61 acres across three contiguous parcels. Strategically positioned at the high-traffic intersection of State Road 19 and St. Johns Avenue, this property boasts exceptional visibility and significant redevelopment potential in one of Putnam County’s fastest-growing areas. Parcel 1 features a 0.93-acre lot improved, zoned C-4 Commercial Intensive, with a 7,918 sq ft retail building operating as a plumbing and electrical supply business. The structure includes a large reception area, three offices, two bathrooms, a spacious workshop, and ample storage—ideal for retail or showroom use. The lot has a fenced area at the rear housing an additional 2,592 sq ft warehouse with a 420 sq ft canopy. Parcel 2, located at the rear of Parcel 1, is a 0.18-acre vacant lot with no street frontage. This space adds depth and flexibility to the overall site layout, providing further room for outdoor storage, expansion, or potential redevelopment. Parcel 3, at 108 N State Road 19, spans 0.5 acres and includes a former filling station zoned C-2 (Commercial, General Light). This 1,664 sq ft building features large roll-up glass doors, prominent front-facing windows, and a 600 sq ft canopy—ideal for automotive, retail, or service-oriented business uses. The entire offering presents abundant paved parking, prominent street exposure, and is strategically positioned in one of Palatka’s busiest commercial corridors. The parcels may be purchased together for $3,000,000 or separately, with Parcel 3 offered at $1,250,000 and Parcels 1 & 2 combined at $1,750,000. If re-parceling is desired to achieve a specific size or frontage, the seller will consider with a reasonable offer. The sale includes real estate only; no business, assets, or equipment will convey. The existing business will vacate upon sale. Owner financing may be considered with a minimum 20% down payment. This is a rare investment opportunity to acquire a highly visible, versatile commercial property with significant existing infrastructure and substantial upside for redevelopment, expansion, or repurposing.
Exceptional Commercial/Flex Space Opportunity in Palatka's Growing Port District Unlock the potential for your business with this expansive 9,050 sq. ft. commercial/flex space situated on a substantial 3.19-acre lot. Zoned M-1 (Light Industrial), this former Bellsouth/AT&T building offers a versatile footprint ideal for a wide range of uses, from corporate headquarters and technical schools to call centers and beyond. Boasting approximately 100 paved parking spaces, accessibility is a breeze for both employees and clients. The property also features a fully fenced back parking lot, providing added security and storage options. A convenient covered canopy over the loading dock ensures efficient and protected deliveries and operations. Here's a listing description for that impressive commercial property: Exceptional Commercial/Flex Space Opportunity in Palatka's Growing Port District Unlock the potential for your business with this expansive 9,050 sq. ft. commercial/flex space situated on a substantial 3.19-acre lot. Zoned M-1 (Light Industrial), this former Bellsouth/AT&T building offers a versatile footprint ideal for a wide range of uses, from corporate headquarters and technical schools to call centers and beyond. Boasting approximately 100 paved parking spaces, accessibility is a breeze for both employees and clients. The property also features a fully fenced back parking lot, providing added security and storage options. A convenient covered canopy over the loading dock ensures efficient and protected deliveries and operations. Inside, the existing layout includes several large conference rooms perfect for meetings and training, ample storage rooms to keep your operations organized, numerous private offices, two large gang bathrooms, and a dedicated break room. Strategically located in the City of Palatka, this property benefits from its prime position near the barge port. Anticipate significant growth in this area once the Shands bridge is replaced, opening the port to larger vessels and increased economic activity. 1 Enjoy excellent connectivity with HWY 17 just a half-mile away, providing convenient access to regional transportation networks. Don't miss this exceptional opportunity to establish or expand your business in a dynamic and evolving location. This property offers the space, zoning, and strategic advantages to propel your organization forward. Schedule your showing today!
Rare opportunity to own a unique & highly visible piece of property on heavily traveled State Rd 19. Three parcels totaling 1.37 +/- acres, zoned C-2. Property has access from both State Rd 19 with 175 +/- ft of frontage & Moody Rd with 124 +/- ft of frontage. Moody Rd is also a main access to the entrance of Walmart. Don't miss out on this prime location for great exposure!
Courtesy: Golf 1, Inc.
321-536-7766
Great for Medical office or else ZONED COMMERCIAL Almost 2,5 acres on heavily traveled Highway. Sellers would carry mtg with balloon for 5 years.
Prime Commercial Property for Sale located in the heart of downtown Palatka, Florida, 607, 609, 613, & 615 St. John's Avenue offers an exceptional opportunity for developers and investors seeking to create a dynamic mixed-use property. This versatile parcel of land is ideally positioned to accommodate a variety of uses, including residential, retail, and office spaces, all within a vibrant, growing community. Situated in the bustling downtown district of Palatka, just steps away from local shops, restaurants, and businesses. The St. John's River is nearby, providing scenic views and easy access to recreational opportunities. Flexible designs and multiple applications, including residential apartments, office spaces, and ground-floor retail. Downtown Palatka is experiencing a surge in interest and revitalization efforts, making it an excellent time to invest in the area. The city's historic charm and proximity to the St. John's River make it an attractive destination.
Prime Commercial Property for Sale located in the heart of downtown Palatka, Florida, 607, 609, 613, & 615 St. John's Avenue offers an exceptional opportunity for developers and investors seeking to create a dynamic mixed-use property. This versatile parcel of land is ideally positioned to accommodate a variety of uses, including residential, retail, and office spaces, all within a vibrant, growing community. Situated in the bustling downtown district of Palatka, just steps away from local shops, restaurants, and businesses. The St. John's River is nearby, providing scenic views and easy access to recreational opportunities. Flexible designs and multiple applications, including residential apartments, office spaces, and ground-floor retail. Downtown Palatka is experiencing a surge in interest and revitalization efforts, making it an excellent time to invest in the area. The city's historic charm and proximity to the St. John's River make it an attractive destination.
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The data relating to real estate for sale on this web site comes in part from the Internet Data Exchange (IDX) Program of the Space Coast Association of REALTORS®, Inc. Real estate listings held by brokerage firms other than the owner of this site are marked with the Space Coast Association of REALTORS®, Inc. logo and detailed information about them includes the name of the listing brokers. Copyright 2026 Space Coast Association of REALTORS®, Inc. All rights reserved.
Palatka is located in Florida. Palatka, Florida has a population of 10,399. Palatka is less family-centric than the surrounding county with 12.62% of the households containing married families with children. The county average for households married with children is 18.89%.
The median household income in Palatka, Florida is $28,082. The median household income for the surrounding county is $39,975 compared to the national median of $69,021. The median age of people living in Palatka is 37.4 years.
The average high temperature in July is 91 degrees, with an average low temperature in January of 45.3 degrees. The average rainfall is approximately 50.6 inches per year, with 0 inches of snow per year.
