INVESTOR OPPORTUNITY! Prime Commercial Lot with Highway Frontage – Endless Potential in the Heart of Town Located right on the main highway in the charming town of Panacea, this 100' x 100' vacant commercial lot offers outstanding visibility and accessibility for your next business venture. Zoned C-2 General Commercial, it allows for a wide range of uses—from retail shops and offices to restaurants, medical clinics, and more. See attached documents for county zoning allowances. City water and sewer are available, and the popular county bike trail runs directly in front of the property—providing excellent foot traffic and built-in community appeal. With flexible zoning, utility access, and a high-profile location, this lot is ideal for entrepreneurs or investors looking to make a strategic move in a growing area. Whether you're envisioning a cozy café, boutique, professional office, or mixed-use development, this location puts your business in the spotlight. Seller may finance with full price offer and substantial down payment.
Many possibilities to be discovered with this commercial property in Panacea FL. Excellent location for most any type of business adventure. Equipped with two bay doors, car lift, and storage space.. The rear of the property offers a 1 bedroom, 1 bath studio apartment. Double lots with great road frontage on US HWY 98 ( Coastal HWY)
Highway frontage Commercial/Residential property! TWO PARCELS! This very unique piece of property is turn key! Completely fenced in with camper hook up. Downstairs has an open floor plan with a kitchen, Florida room, large roll up door and much more! Upstairs features an apartment with a beautiful deck to drink coffee and watch the sunrise, an open living area, kitchen, walk in shower, and a brand new stackable washer and dryer set. Parcel 24-5S-02W-058-03033-001 is included, totaling almost half an acre! With over 4,000 square ft, the options are endless! Golf cart community with boat ramps and waterfront restaurants. Minutes away from beaches!
Great commercial lot with 70ft highway frontage on the busy Coastal Highway. The lot is approx 160ft deep and would be great for a small business to build on. Just past the Dollar General on the right in the Heart of downtown Panacea.
Great commercial lot with 70ft highway frontage on the busy Coastal Highway. The lot is approx 160ft deep and would be great for a small business to build on.
Vacant commercial property with many possible uses. Showroom/Retail space on first floor and a community residence upstairs with two bedrooms, one bath and living, dining and kitchen area with separate entry and screened porch. Additional garage could be used for a shop area. Make it whatever space you want it to be! Located in the central business district in Panacea with two lots for ample parking space.
Fantastic Commercial Property located on Coastal Hwy in downtown Panacea! Ideally suited for development.
Oh the possibilities this property has!! Commercial property with 3 BR/2 BA home. Located in Panacea on Hwy 98 with 150 feet of road frontage. The 3000 sq foot shop has four roll up doors in front, two in back. Home & Shop have total 8 lots. Additional adjacent lots available. Great potential for RV park.
6000 sqft of commercial space. 150ft of prime highway frontage. Gorgeous marsh views. Includes office space, a break room, kitchen, bar, and over 800 sqft of coolers, equipment, industrial sinks, and cleaning tables. Includes lots 33-36 and the parcel just north on the corner. Property will need to be rewired. More pictures to follow.
This building would be a perfect spot for a bank, restaurant, doctor/medical services, retail office or business. Formerly a bank with all fixtures of a bank.

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Panacea is located in Florida. Panacea, Florida has a population of 1,050. Panacea is less family-centric than the surrounding county with 9.22% of the households containing married families with children. The county average for households married with children is 32.02%.
The median household income in Panacea, Florida is $31,976. The median household income for the surrounding county is $72,941 compared to the national median of $69,021. The median age of people living in Panacea is 46.6 years.
The average high temperature in July is 92.1 degrees, with an average low temperature in January of 37.9 degrees. The average rainfall is approximately 59.1 inches per year, with 0 inches of snow per year.