Excellent location for business in city limits! Potential commercial uses: Law firm, Physicians Practice, Medical, Dentist, Insurance, Real Estate, Retail, Restaurant, etc. One story building currently subdivided for 3 businesses, but can be combined for more flexibility on floor plan layout. Building is now vacant with many possibilites. Ample parking in front of building.
Step into a piece of Barbourville history with this incredible opportunity at 222 Knox Street, a distinguished three-story commercial building located just two blocks from the courthouse square in the heart of downtown. Listed on the National Register of Historic Places, this Romanesque Revival gem was built in 1910 and originally housed the First State Bank. Its architectural charm shines through in the arched brick entryway, detailed stonework, and distinctive window bays, all telling a story of craftsmanship and legacy. With over 4,800 square feet of usable space across three levels, the layout is ideal for a wide range of uses—from a boutique or café on the ground floor to office suites or residential lofts above. The property includes three floors: a storefront-style ground level, a second level formerly used as office space, and a top floor with former residential apartments. Whether you envision a creative mixed-use development, professional workspace, or a one-of-a-kind short-term rental destination, this building offers historic character with endless potential. Located within Barbourville's charming commercial district, surrounded by shops, local businesses.

Barbourville is located in Kentucky. Barbourville, Kentucky has a population of 3,048. Barbourville is less family-centric than the surrounding county with 5.45% of the households containing married families with children. The county average for households married with children is 33.09%.
The median household income for the surrounding county is $29,206 compared to the national median of $69,021. The median age of people living in Barbourville is 42.2 years.
The average high temperature in July is 86.9 degrees, with an average low temperature in January of 24.5 degrees. The average rainfall is approximately 50.8 inches per year, with 9.9 inches of snow per year.