Courtesy: Seaport Village Realty
508-771-1994
Beautifully renovated second-floor professional office spaces available in a prime Hyannis location. Three units ($1000 monthly rent for each) averaging approximately 270 sq ft. each. Ideal for attorneys, accountants, therapists, or other professional uses.The building features a welcoming shared waiting area. Each unit is equipped with its own brand-new mini-split system for efficient heating and air conditioning. One of the units with a beautiful custom bookcase cabinetry and abundant natural light from a large window.Tenants benefit from all-inclusive utilities, including heat, A/C, electricity, and high-speed internet. Shared bathroom facilities are conveniently located on first level. Excellent central location close to major routes, businesses, and local amenities, offering both convenience and visibility. Turnkey opportunity for professionals seeking a modern, move-in-ready workspace.
Courtesy: Premier Commercial
508-815-5700
PRIME DOWNTOWN HYANNIS COMMERCIAL PROPERTY. Multiple Use Potential. Unlock the possibilities with this versatile commercial property, ideally situated in the heart of downtown Hyannis. Available leasable space is 1,464 sq ft. Formerly a successful dental office, this well-maintained space is perfect for a wide range of professional, medical, or business uses.Conveniently located just steps from bustling Main Street, Hyannis Harbor, Cape Cod Hospital, and a short distance from the Route 28 commercial corridor, this location offers high visibility and easy accessibility for clients and customers. Enjoy seamless access to the Mid-Cape Highway, making regional travel a breeze.Key features include:*Flexible floor plan*Off-street parking for staff and clients*Established professional setting with existing infrastructure for healthcare or office use*Walkable to restaurants, shops, ferry terminals, and public transportationWhether you're expanding your practice, launching a new venture, or investing in a prime Cape Cod location, this property checks the boxes.
Courtesy: Coastal Point Properties, LLC
508-258-9500
Exceptional opportunity to own a highly visible commercial condo in the heart of Hyannis. Located on Main Street Hyannis and moments from Hyannis Harbor, this retail space offers outstanding exposure with strong pedestrian and vehicle traffic year-round.Features include a prominent storefront with large display windows, excellent signage potential, and a flexible open layout suitable for retail, boutique, office, gallery, or service-based businesses. Surrounded by popular shops, restaurants, waterfront attractions, ferry terminals, and public parking, this location benefits from both local and seasonal Cape Cod traffic.Position your new or existing business in Hyannis' thriving commercial and cultural hub and take advantage of the visibility, accessibility, and vibrant downtown energy this prime location provides.Buyer/Buyers agents to verify all information.
Courtesy: Coastal Point Properties, LLC
508-258-9500
Exceptional opportunity to own a highly visible commercial condo in the heart of Hyannis. Located on Main Street Hyannis and moments from Hyannis Harbor, this retail space offers outstanding exposure with strong pedestrian and vehicle traffic year-round.Features include a prominent storefront with large display windows, excellent signage potential, and a flexible open layout suitable for retail, boutique, office, gallery, or service-based businesses. Surrounded by popular shops, restaurants, waterfront attractions, ferry terminals, and public parking, this location benefits from both local and seasonal Cape Cod traffic.Position your new or existing business in Hyannis' thriving commercial and cultural hub and take advantage of the visibility, accessibility, and vibrant downtown energy this prime location provides.Buyer/Buyers agents to verify all information.
Courtesy: Premier Commercial
508-815-5700
The first floor features a licensed space for 70 seats, plus an additional 24 outdoor patio seats, along with a full commercial kitchen ready for your restaurant concept. The recently remodeled second floor offers flexible space that can be used for storage, office use, or as a residential unit with one bedroom and a full bath.Located in the heart of Downtown Main Street, Hyannis, this property is close to local attractions, island ferries, Hyannis Municipal Airport, shopping, and entertainment. Easy to show! Bring your restaurant vision to 517 Main Street and make it a reality in 2026!
Courtesy: Lamacchia Realty, Inc.
508-548-3415
Multiple Units Available - Please review attached floor plan. Unit 6 - 3000 Sq. Ft. Office and Showroom area. From private offices, to showroom areas, to a private gym. Endless possibilities in this expansive unit. Over engineered building utilities allows for a lot of different options.
Courtesy: Commercial Realty Advisors, Inc.
508-862-9000
Offered for sale is a highly visible +/-6,300 SF masonry commercial building located in the heart of Downtown Hyannis on Main Street. Situated on +/-0.33 acres within the Downtown Main Street zoning district and the Downtown Hyannis Growth Incentive Zone, this property benefits from strong foot traffic, excellent frontage, and proximity to Hyannis Harbor, ferry terminals, hotels, retail, and year-round attractions. Originally constructed in 1987 and renovated in 2016, the building is well-suited for continued restaurant, hospitality, or repositioned commercial use. The property offers municipal utilities, on-site parking, and established site infrastructure. This is a rare opportunity to acquire a core downtown asset in a supply-constrained market with long-term redevelopment and investment upside. Asking price is $1,999,000. Sale includes real estate only; the operating business known as Fresh Ketch is not included.
Courtesy: Premier Commercial
508-815-5700
End Commercial Business Bay / Office Unit at Communication Way Industrial Development now available for sale. First Unit as you turn into this sought after business condo development located right off of Industrial Drive, Hyannis, Cape Cod, MA, USA. Fantastic light at end of the building, many windows and 1,414 of square footage spread out over two floors. Floor plans available. The Unit has great frontage, signage and situated at the front entrance of the Communication Way Industrial Development. Multiple offices, overhead door to rear and mezzanine space upstairs make this a wonderful unit to own. Perfect for trades, storage, sales, or business start up. Location is close to US Route 6 exits 6 and 7. Purchase to have your business here or as an investment and receive passive income. Easy to show, many recent upgrades. Make it happen for you in 2026!
Courtesy: Premier Commercial
508-815-5700
An exceptional opportunity to lease restaurant space complete with full commercial kitchen. There is no business to buy. Take the keys and open your restaurant! It's a blank canvas for your creative spirit!Located at the intersection of Main and Sea Streets, this 4,200 SF ground-level space boasts strong corner presence, oversized windows, and prominent frontage on two of the area's busiest commercial corridors.Situated in the Hyannis Main Street Business Improvement District (BID), the property is surrounded by local shops, restaurants, galleries, and civic destinations. It's a high-foot-traffic area with both seasonal tourism and strong year-round local activity.Walking distance to:-Sea Street Beach, Veterans Park, and Kalmus Beach-Hyannis Harbor & ferry service to Nantucket and Martha's Vineyard-JFK Hyannis Museum, Cape Cod Maritime Museum-Banks, municipal buildings, post office, public transportation
Courtesy: Commercial Realty Advisors, Inc.
508-862-9000
This fully occupied professional office building delivers stable income with a 7.5% capitalization rate.Anchored by a popular FM radio station with extensive IT infrastructure, the +/-2,766 SF property sits on a 0.53-acre parcel in Hyannis' Downtown (DN) zoning district. The tenant's long-standing presence provides both financial security and operational stability.Highlights for Investors:Income-Producing Asset: Fully leased with reliable cash flow.7.5% Cap Rate: Competitive return in a high-demand Cape Cod market.Established Occupant: Well-known broadcast station with specialized infrastructure in place.Prime Location: Situated in downtown Hyannis, close to business, healthcare, and municipal hubs.Historic Character, Modernized Functionality: Originally built in 1910, effectively updated in 1984.This offering represents a turnkey, low-management Hyannis investment with a respected tenant and attractive returns in one of Cape Cod's strongest commercial corridors.
Courtesy: Premier Commercial
508-815-5700
An exceptional opportunity to own a high-visibility corner commercial condominium in the heart of downtown Hyannis, Cape Cod's economic and cultural hub. Located at the intersection of Main and Sea Streets, this 4,200 SF ground-level space boasts strong corner presence, oversized windows, and prominent frontage on two of the area's busiest commercial corridors.This is a real estate-only offering.Situated in the Hyannis Main Street Business Improvement District (BID), the property is surrounded by local shops, restaurants, galleries, and civic destinations. It's a high-foot-traffic area with both seasonal tourism and strong year-round local activity.Walking distance to:-Sea Street Beach, Veterans Park, and Kalmus Beach-Hyannis Harbor & ferry service to Nantucket and Martha's Vineyard-JFK Hyannis Museum, Cape Cod Maritime Museum-Banks, municipal buildings, post office, public transportationPlease refrain from speaking with staff about space for sale.
Courtesy: Premier Commercial
508-815-5700
COMMERCIAL CONDOMINIUM FOR SALE now available for sale or lease. Lease Option to Purchase also possible. Great floor plan. Unit 19 - 2,787 sq. ft., Class A building Office / Retail buildout with offices, kitchen and two ADA restrooms. Ample paved parking HBV zoning allows for multiple uses. Walking distance to restaurants and shops and a half a mile from the Cape Cod Hospital. Also close to island ferry service. Stop paying rent and invest in your company or relocate to this ideal spot. Great frontage, signage and location! Easy to show!
Courtesy: Premier Commercial
508-815-5700
FOR LEASE NEW CONSTRUCTION RETAIL / RESTAURANT SPACE AVAILABLE AT STAPLES PLAZA HYANNIS! Join the vibrant retail landscape at Staples Plaza, strategically positioned at the Airport Rotary where Rt 28, Rt 132, and Barnstable Road intersect. This prime location forms part of one of the region's largest retail hubs, featuring renowned brands like Staples, TJ Maxx, Work Gear, Ocean State Job Lot, Subway, Golf for Less, and more. Situated directly across from the Barnstable Municipal Airport and in close proximity to US Route 6 Exits, downtown Hyannis, retail corridors of Route 28 and Route 132, and Island Ferry Service, Staples Plaza offers unparalleled visibility and accessibility. Exciting leasing opportunities await in the newly constructed Building 2, with a 2,127 SF Retail Unit and a 2,406 SF Restaurant Unit. Whether you prefer the entire space or a subdivided option, these units will be delivered in vanilla box condition, allowing tenants to customize the interior buildout to suit their needs. Boasting high traffic counts, parking, exceptional frontage, prominent signage, and a strategic location, these units are ideal for tenants seeking prime retail or restaurant space!
Hyannis is located in Massachusetts.
