Courtesy: Edge Realty
573-335-8111
Location and visibility set this property apart. This prime riverfront commercial asset offers over the perfect location for downtown development and parking, making it well suited for a wide range of uses. Situated directly along the Mississippi River, the property presents exceptional potential for office, restaurant, warehouse, or mixed-use concepts and has a warehouse currently on the property. Opportunities like this are rare so don’t miss the chance to secure a highly versatile riverfront commercial property.
Courtesy: Edge Realty
573-335-8111
Location and visibility set this property apart. This prime riverfront commercial asset offers over 7,000 square feet of flexible space with three oversized overhead doors and an additional loading dock, making it well suited for a wide range of uses. Situated directly along the Mississippi River, the property presents exceptional potential for office, restaurant, warehouse, or mixed-use concepts. Convenient parking is available on both the north and south sides of the building, enhancing accessibility for staff and customers alike. Opportunities like this are rare so don’t miss the chance to secure a highly versatile riverfront commercial property.
Courtesy: Edge Realty
573-335-8111
*All Commercial spaces leased *One residential unit ideal for owner occupancy, long term rental or AirBnb *Opportunity to increase NOI through rent growth and residential income *Centrally located *Strong local rental demand supports future income growth *Ideal for investor seeking stabilization plus upside
Courtesy: Edge Realty
573-335-8111
Situated in the heart of historic downtown Cape Girardeau, 20 North Spanish Street offers a rare opportunity to own a well designed and versatile commercial space. This 7,396 square foot building is thoughtfully configured into three distinct areas: a 60 seat banquet space, a 135 seat main dining area, and a dedicated bar section. A covered outdoor patio provides seating for an additional 25 guests. The property is already configured in a way that allows it to be easily divided into two separate units if desired. The kitchen is centrally located with direct access to both the main dining room and banquet area, creating an efficient layout for service and operations. Constructed with I-beam support, the building also allows for flexibility in opening the floor plan to suit a variety of concepts.
Courtesy: Lorimont L.C.
573-334-5200
0.46 acre tract (two lots) near Shogun between busy Independence and William St. Zoned C-1 with approximately 119 feet of road frontage. Adjoining Lot 1 is also for sale for $130,000. Perfect central Cape location!
Courtesy: Lorimont L.C.
573-334-5200
0.53 acre lot next to Shogun between busy Independence and William St. Zoned C-1 with approximately 138 feet of road frontage. Adjoining Lots 2 and 3 are also for sale for $130,000. Perfect central Cape location!
Courtesy: Area Properties Real Estate-River Region
573-803-3353
BINGO! This one is a winner! Offering 20,352 square feet of versatile commercial space with approximately 88,500 square feet of concrete parking accommodating up to 200 vehicles, all situated on 4+ acres in a highly convenient Cape location. The steel framed building is ADA compliant, sprinkled and features basic kitchen facilities along with large restroom areas, making it ideal for a wide range of potential uses. Priced below its most recent appraisal. Check this one out B-4 you miss this great opportunity.
Courtesy: Landmark Real Estate Group Residential
314-965-9110
Courtesy: Edge Realty
573-335-8111
Discover a versatile investment opportunity on Broadway! The upper level features a beautifully remodeled 1 bedroom apartment complete with hardwood floors, exposed brick accents, and a private entrance...perfect for rental income or an owner occupant. The street level commercial space offers excellent visibility with prominent Broadway frontage and expansive display windows, ready to be reimagined and finished to suit your business or tenant needs. So much potential in a prime location!
Courtesy: Owens Realty Co.
573-335-9111
Turnkey Restaurant & Bar for Sale – Ready for You to Take Over! Are you ready to own a thriving business with minimal hassle and maximum potential? This fully operational restaurant and bar is the perfect opportunity for an entrepreneur looking to dive straight into a fully equipped and profitable venture. Why is this a great opportunity? Turnkey Operation: Everything is already set up and ready to go! From the kitchen to the bar, the front-of-house to the back office, we’ve taken care of all the details so you can start operating immediately with no need for additional setup or costly delays. Fully Furnished & Decorated: Step into a fully furnished, stylishly designed space that is ready for guests. From tables and chairs to décor, lighting, and artwork, every element has been carefully curated to create the perfect atmosphere for dining and drinks. Spacious Outdoor Bar & Patio: Make the most of the beautiful weather with a large outdoor bar and patio area. Perfect for hosting live events, happy hours, or simply offering guests a relaxed environment to enjoy great food and drinks. It’s a huge bonus that will help increase foot traffic and enhance the overall guest experience. Turnkey Bar Setup: The bar is fully equipped with everything you need to serve up amazing cocktails and craft beverages. Whether you’re a mixologist or simply love great drinks, this bar is ready to impress! Prime Location: Situated in a high-traffic area, this restaurant and bar has been attracting a steady stream of loyal customers and is well-known in the community. This is your chance to step into an established, profitable business with everything already in place. With a beautiful outdoor space, a fully functional bar, and an inviting interior, this place has all the ingredients for success.
Courtesy: RE/MAX Platinum
636-441-8080
Prime Commercial Auction Opportunity – 1931 Kingshighway, Cape Girardeau, Missouri This is more than a property. It is an opportunity to be part of Cape Girardeau’s expanding commercial corridor and invest in one of southeastern Missouri’s most dynamic markets. Located along North Kingshighway, 1931 Kingshighway places you in the center of a thriving business hub that serves as the commercial backbone of Cape Girardeau. This stretch of roadway is among the highest traffic corridors in the region, connecting Interstate 55 to the city’s active retail, restaurant, and service districts. The property offers outstanding exposure, easy access, and direct connection to the businesses and neighborhoods that drive the local economy. The parcel totals approximately 32,400 square feet (.74 Acres +/-) and is zoned C2 Highway Commercial, one of the city’s most versatile zoning designations. This allows a wide variety of uses including retail storefronts, offices, service operations, and mixed use redevelopment or new construction projects. The existing building has recently been opened up, providing a strong structure and flexible interior that can be repurposed, remodeled, or completely transformed. Whether you are a local business owner ready to establish your next location, an investor seeking to reposition a property in a proven corridor, or a developer looking for a prime site with strong fundamentals, this property delivers a compelling value. Surrounding the site are national retailers, restaurants, and service businesses that anchor this active commercial area. Major employers, healthcare facilities, and Southeast Missouri State University all contribute to the steady daytime population and economic activity that keep Kingshighway moving. Cape Girardeau’s role as a regional hub attracts shoppers, professionals, and visitors from across multiple counties, creating a constant flow of traffic and opportunity. Infrastructure and access are excellent. Kingshighway provides multiple entry and exit points, and the property’s location offers convenient access to downtown Cape Girardeau, Interstate 55, and nearby retail centers. The visibility and signage potential here are exceptional, perfect for any brand that wants to stand out and be seen. Cape Girardeau continues to experience steady commercial growth with a balanced economy supported by healthcare, education, logistics, and regional retail. The city’s planning and development programs have maintained a business friendly environment that encourages investment and redevelopment along major routes such as Kingshighway. That forward momentum makes properties like this increasingly rare. 1931 Kingshighway represents a unique chance to capture one of the last flexible parcels in a proven, high traffic location. With C2 Highway Commercial zoning, strong demographics, and unmatched exposure, the possibilities are wide open. Do not miss this opportunity to buy at auction with a reserve price in place. Whether your goal is to operate, lease, or build, this property offers the foundation for long term success in one of Missouri’s strongest regional markets.
Courtesy: Lorimont L.C.
573-334-5200
Presenting an exciting opportunity for retail and restaurant investors! This impressive 6,167 SF property, with coveted C2 zoning, offers a versatile canvas for your commercial aspirations. Situated in the heart of Cape Girardeau, this meticulously maintained building is perfectly poised to accommodate a thriving business. The generous square footage allows for ample customization, while the prime location promises excellent visibility and accessibility. With its strategic placement, this property is primed to attract the foot traffic essential for retail or restaurant success. Unlock the potential of this outstanding investment opportunity and take the next step in realizing your business vision.
Courtesy: EXP Realty, LLC
866-224-1761
Discover endless potential with this versatile commercial property in a prime, high-visibility location, tucked right off Kingshighway and conveniently situated between Independence St and Broadway. The front area welcomes customers or clients with an open, flexible layout ideal for retail, a showroom, or professional office space. Behind it, a spacious attached warehouse provides ample room for storage, inventory, light production, or contractor equipment, complete with easy access for deliveries. Whether you’re envisioning a small doctor’s office, contractor headquarters, business offices, or a service-based operation, this property offers the rare combination of visibility, functionality, and room to grow, all in one convenient spot.
Courtesy: EXP Realty, LLC
866-224-1761
In the heart of downtown and just steps from dining, shopping, and campus life, this fully renovated 11-bedroom property offers a rare combination of size, location, and versatility. Formerly a medical facility, this solid, slab-built structure was completely transformed in 2020 into a high-demand sorority house, making it a proven income-producing asset for its current owners. Spanning over 5,100 square feet, the home features bedrooms thoughtfully arranged along the perimeter for privacy, while the center of the home offers a spacious living room, dining area, and oversized kitchen with a butler's pantry. A bright, inviting sunroom stretches across the back. With three bathrooms, one half bath, and two laundry rooms, the layout is designed for high occupancy and convenience. Situated on a generous lot with twenty-five parking spaces, this property is perfectly suited for group housing, co-living arrangements, student rentals, or even a conversion back into professional office or medical space. Whether you're an investor seeking strong rental income, an organization in need of housing, or a visionary ready to adapt this space to your unique use, this property offers unmatched flexibility in one of the most desirable locations in town. Property is owned by licensed Realtors.
Courtesy: Semo Home Realty
573-803-3291
Spacious Office with Bonus Apartment! This versatile commercial property offers everything your business needs: a large conference room for meetings or trainings, two private offices, a welcoming front-desk reception area, and a kitchen/break room for staff convenience. Guests and employees will appreciate the modern, well-appointed bathroom. The lower level provides abundant storage and utility space plus a one-bed/one-bath apartment that was previously rented for $850/month — ideal for additional income, on-site staff housing, or expanded office use. Don’t miss this unique opportunity to own a property that blends professional space with income potential!
Courtesy: Edge Realty
573-335-8111
Leased office building located just off North Kingshighway. The property is two stories with 21 units, including lower-level garage space. Parking lot with approximately 20 spaces, with the option to increase capacity by adding angled parking in the rear. With its strong location and future growth options, this property is an excellent opportunity for investors seeking long-term value.
Courtesy: Lorimont L.C.
573-334-5200
Great redevelopment opportunity in Gordonville just outside Cape Girardeau, MO. This property consists of a 1,510 square foot former auto shop and 3,412 square feet of storage on 1.3 acres. The corner frontage is fit for retail, fuel/c-store, or strip center development, and the lack of zoning provides flexibility for a wide range of business needs, including multi-family development. This property's strategic location at the busy intersection of MO-25 and Highway Z offers direct access to Gordonville services as well as high traffic and a thriving commercial corridor between Jackson and Cape Girardeau. With a commanding visible corner, this property is poised to accommodate mixed or multiple uses. Don't miss out on the chance to secure this unique property!
Courtesy: Lorimont L.C.
573-334-5200
Prime investment and development opportunity near Gordonville in Cape Girardeau, MO. Two tracts totaling 7.4 acres sit at the roundabout at the corner of Route K and State Highway 25. A 5,130 SF metal building offers versatile potential for office, office/warehouse, retail, or day care use. The corner frontage is fit for retail, fuel/c-store, or strip center development, and the lack of zoning provides flexibility for a wide range of business needs. Additional included wooded acreage sits behind Acee's and would be suitable for residential development. This property's strategic location offers access to high traffic and a thriving commercial corridor between Jackson and Cape Girardeau with a commanding visible corner fit for mixed uses. Don't miss out on the chance to secure this unique property!
Courtesy: Edge Realty
573-335-8111
3.9 acres located in Cape's industrial park just off Kingshighway with close proximity to I-55 and Hwy 74, featuring a 7,500 sq. ft. industrial warehouse. The building is in need of repairs but offers a solid foundation with a concrete floor and durable steel structural frame.
Courtesy: Edge Realty
573-243-2555
Don't miss this exceptional opportunity to purchase a versatile 1800 sq ft commercial building in the heart of Cape Girardeau. This highly desirable property offers an ideal location for your business, providing excellent visibility and accessibility for your customers. Whether you're looking to establish a new retail storefront, set up professional offices, or expand your service-based business, this space is designed to accommodate a wide range of ventures. Key features: 1800 sq ft of adaptable space: Configure the layout to perfectly suit your operational needs. Easy access: Convenient to both customers and employees. Ample parking. Well kept and clean. Cape Girardeau is a thriving community with a strong economy and growing population, making it an ideal place to grow your business. This commercial building offers the perfect foundation for your success. Ready to elevate your business? Contact us today to schedule a private showing and see how this prime commercial space can meet your needs!
Courtesy: Seasons Home Realty, Llc
This incredible property, located on 2 lots in doctors park, could be two separate offices. Main floor contains a vestibule, waiting room, business office, 3 exam rooms, x-ray room, 2 surgery rooms, 4 private offices, a consultation room, nurses station, lab, and 3 restrooms. Lower level contains a waiting room, business office, 3 exam rooms, 3 offices, surgery room, recovery room, two break rooms, 3 restrooms, two utility rooms, and 3 storage areas. Each floor has it's own entrance and parking area The parking is 17,500 square feet with plenty of parking for each floor. This property is in a highly visible area in Doctors Park right next door to Doctors Park Surgery Center. Location: Business Park, High Traffic
Courtesy: MISPRFM01
"Investment Opportunity" Are you in search of a turn-key operation? This carwash is positioned on approximately .511 acre on a corner lot with a high traffic count. It features a five-bay self-wash with options for quarters, credit, and debit cards. The facility boasts new equipment inside the building, hoses in the bays, and a new bill-coin changer. Location: City, Corner Location, High Traffic
Courtesy: Century 21 Ashland Realty
573-334-2121
Inspire innovation and productivity in a space that merges convenience and community. Continue the legacy of the original purpose, or re-establish this for other endeavors. This is a great opportunity for educational establishments, non-profit organizations, creative office space, meeting center, and community outreach with endless space, parking, and modern functionality. This space deserves to be dedicated to a greater good, possibility providing a home for organizations committed to making a positivity impact on our community. Featuring over 43,000 square feet building situated on 6.517 acre lot. Original structure built in 1978 with the final 24,000 sq ft, 2 story expansion completed in 2008. Some Accessible Features Location: Suburban
Courtesy: Lorimont L.c.
573-334-5200
13,694 SF, single level commercial building with multiple entrances from 3 separate streets, Main, Independence and Water Streets. Large open areas and office areas that makes this property suitable for various uses and businesses. Features on-street parking along with access to a huge downtown municipal off-street parking lot just across from the building. Located in historical downtown Cape Girardeau adjacent to the riverfront wall. Although the past use was for a customer service operation center, it is suitable for other types of various uses and businesses. Location: Downtown
Courtesy: Edge Realty
573-335-8111
Corner lot property on Broadway with high visibility and a high traffic count of 5300 cars per day. CBD zoned. Tenant is an operational restaurant. Location: City, Downtown, High Traffic
Cape Girardeau is located in Missouri. Cape Girardeau, Missouri has a population of 39,415. Cape Girardeau is less family-centric than the surrounding county with 27.55% of the households containing married families with children. The county average for households married with children is 31.66%.
The median household income in Cape Girardeau, Missouri is $48,055. The median household income for the surrounding county is $59,252 compared to the national median of $69,021. The median age of people living in Cape Girardeau is 33.9 years.
The average high temperature in July is 89.5 degrees, with an average low temperature in January of 24 degrees. The average rainfall is approximately 48.3 inches per year, with 10.3 inches of snow per year.
