Courtesy: GASLIGHT REAL ESTATE
Lindy Lile
660-646-1417
VERSATILE COMMERCIAL PROPERTY WITH OFFICE & STORAGE SPACE Take advantage of this versatile commercial property located at 28 Third Street in Chillicothe, Missouri. Offering a functional combination of office and storage space, this property provides flexibility for a variety of business uses. The building features three separate office spaces along with two half bathrooms, providing a practical setup for daily business operations. In addition, there are three separate storage areas, each with an exterior entrance, making it easy to access equipment, inventory, supplies, or materials without disrupting the main office areas. The entire property is completely fenced, adding security and making the site especially appealing for businesses needing protected outdoor space, equipment storage, service vehicles, or additional work areas. Whether you're looking for space for a contractor, service business, property management company, maintenance operation, small distribution business, office headquarters, or investment property, this commercial building offers plenty of possibilities.
Courtesy: United Country Graham Agency
Megan Sensenich
660-247-2448
Unlock the potential of this highly visible commercial property! Situated on approximately 0.68 acres with outstanding frontage along Highway 65 and convenient access just off Highway 36, this location offers excellent exposure for your business and easy accessibility for customers and clients. The 1,344 sq. ft. brick main building features a flexible layout designed to accommodate a variety of professional or service-based businesses. Inside, you'll find four private offices, with three already equipped with sinks and built-in cabinetry, making them ideal for medical, dental, veterinary, wellness, grooming, or salon services. Additional main-level features include a welcoming reception area, half bath, and dedicated records/storage room. The full walk-out basement provides tremendous additional space for storage, equipment, inventory, workshop areas, treatment rooms, kennel space, laundry facilities, or future expansion. With two walk-out doors, a garage door, and existing plumbing in multiple areas, the lower level offers endless possibilities for customization to fit your business needs. Comfort is provided year-round with natural gas heat and central air conditioning. Outside, you'll appreciate the ample parking lot for employees and customers, along with a 53' x 21' pole barn that offers outstanding potential for additional storage, workshop space, inventory, or equipment. A covered carport area behind the building provides even more functional space. Whether you're envisioning a veterinary clinic, medical or dental office, chiropractic or physical therapy practice, counseling center, pet grooming or boarding facility, doggy daycare, beauty salon, daycare center, professional offices, or another growing business, this versatile property is ready for its next chapter. Properties with this level of visibility, flexibility, and location don't come along often. Bring your vision and make this exceptional commercial property your next business success!
Courtesy: Century 21 Farm and Home
Kristy Lauhoff
660-247-1208
Exceptional commercial opportunity on 5.52 acres with excellent visibility from Highway 36, offering outstanding exposure for a variety of business,storage, or investment uses. This versatile property features three buildings designed to accommodate multiple operational needs. Building 1 (105' x 36') includes a new roof installed in 2025, office space, and a half bath, providing a functional workspace ready for immediate use. Building 2 (21' x 24') offers additional office space and a half bath, making it ideal for administrative operations, rental potential, or supplemental business use. Building 3 (182' x 48') is a spacious lean-to structure featuring 13 stalls, perfect for equipment storage, or agricultural operations. The property is fully fenced, providing security and flexibility for a wide range of commercial or agricultural endeavors. With ample acreage, easy access, and high-traffic highway visibility, this property offers endless possibilities for expansion, business growth, or investment. This unique property combines location, functionality, and versatility, making it a rare opportunity in today's market.
Courtesy: Century 21 Team Elite
Melissa Purkapile
660-359-1101
HISTORIC WABASH RAILROAD DEPOT & FREIGHT HOUSE Step into a true piece of Missouri history with the iconic Wabash Railroad Depot and Freight House, originally built in 1909 and sitting on just over an acre of prime real estate. Rich with character and packed with potential, this remarkable commercial property offers a rare opportunity to restore and reimagine one of Chillicothe’s most recognizable historic landmarks. The historic depot features approximately 3,916 square feet and was most recently operated as a restaurant. Inside, many original architectural details and historic features still remain intact, including the railroad switch stand and signaling device, blending timeless railroad-era charm with functional commercial space. The building includes an existing bar area, multiple dining rooms, kitchen and prep spaces, and restrooms. Some restaurant equipment remains with the property, although it has not been utilized for several years. Adjacent to the depot sits the former freight house offering an additional 4,460 square feet of space. While unused for many years, the freight house presents incredible possibilities for restoration, expansion, storage, event use, retail space, offices, workshops, or creative redevelopment. Connecting the two historic structures is an outstanding open-air gathering area full of atmosphere and potential. Featuring original brick footing, a stage area, and the well-known historic Chillicothe, MO sign, this outdoor space could become an incredible entertainment venue, beer garden, concert area, festival space, wedding venue, or community gathering spot. Whether you envision a bar and grill, creating unique office or retail spaces, developing an event destination, or restoring a treasured landmark back to life, the possibilities here are truly endless. Opportunities like this rarely come available — own a piece of railroad history and bring new life to one of Chillicothe’s most iconic properties.
Courtesy: RE/MAX Town and Country
Bobbi Meneely
660-752-5467
Historic Downtown Investment Opportunity Rare chance to own a 13,440 sq ft, three-story commercial building overlooking the vibrant downtown city square in Chillicothe. This versatile mixed-use property offers immediate income potential with 7 occupied office/retail spaces on the main level, providing established cash flow from day one. The second and third floors feature expansive unfinished open spaces ready for redevelopment and customization. Endless possibilities include: event venue or entertainment space, large-format retail or showroom, indoor storage units, creative loft offices or coworking space, multi-unit residential apartments or mixed-use housing, boutique hotel or short-term rental concept. With prominent visibility, strong downtown presence, and flexible zoning potential, this property is ideal for investors, developers, or entrepreneurs seeking a value-add opportunity in a growing community. Positioned in the heart of downtown Chillicothe, this landmark building combines historic charm, income-producing tenants, and significant upside potential.
Courtesy: Century 21 Team Elite
Melissa Purkapile
660-359-1101
Turn-Key Restaurant & Lounge Opportunity in Northwest Missouri! Here is your chance to own a well-established, turn-key restaurant and lounge in the heart of Northwest Missouri. This property is a fully operational successful dining and entertainment venue offering a complete commercial kitchen, full-service bar, and spacious indoor and outdoor patio dining areas — everything needed to step in and start operating immediately. This approximately 6,240 sq ft commercial building features an expansive fully equipped kitchen, bar area, over 400 seating capacity dining space, five restrooms, Toast POS System, complete camera system, and concrete parking lot, making it ideal for restaurant, bar, catering, or event-based business opportunities. The layout allows flexibility for private parties, live entertainment, and special events, creating multiple revenue streams. Known locally for its welcoming atmosphere, live music events, and quality dining, this business has built a strong customer base and community presence. The property also offers ample parking and great accessibility in a community that is based around two major highways. Whether you're an experienced restaurateur or looking to invest in a thriving hospitality business, this turn-key opportunity provides everything needed to hit the ground running with proven income records. Current owner is offering 60 days of training and consultation for a seamless transition. Don't miss this rare opportunity to own a ready-to-operate restaurant and lounge in a growing Northwest Missouri community.
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Chillicothe is located in Missouri. Chillicothe, Missouri has a population of 9,253. Chillicothe is less family-centric than the surrounding county with 27.42% of the households containing married families with children. The county average for households married with children is 29.05%.
The median household income in Chillicothe, Missouri is $48,699. The median household income for the surrounding county is $54,309 compared to the national median of $69,021. The median age of people living in Chillicothe is 38.4 years.
The average high temperature in July is 88.1 degrees, with an average low temperature in January of 17.2 degrees. The average rainfall is approximately 40 inches per year, with 14.6 inches of snow per year.
