Versatile commercial/mixed-use investment opportunity in a highly visible Jackson location! This property offers an attractive combination of existing rental income and future owner-operator potential, making it well suited for investors, entrepreneurs, or business owners looking for flexibility. The upper level features a 3-bedroom, 2-bath residential unit that is currently rented, providing established income from day one. The lower level offers commercial space with a flexible layout, multiple rooms and work areas, and two additional bathrooms, including one with a walk-in shower. The configuration lends itself to a variety of potential commercial uses while offering the unique advantage of residential rental income above. Located along W. Jackson Boulevard near Jackson High School, the property benefits from excellent visibility, convenient access, and ample off-street parking. The combination of commercial and residential space creates multiple possibilities—continue operating it as an income-producing investment, establish your own business on the lower level while collecting rent upstairs, or utilize the property as part of a larger investment strategy. With existing rental income, commercial space, a 3-bedroom residential unit, ample parking, and a strong Jackson location, this property offers the versatility investors and owner-operators are looking for. Schedule your showing and explore the possibilities!
Remarkable building with many possible use options. Extensive remodeling, upgrading has been completed. The main building features over 2500 sq ft with central heat, air, and small storm cellar. 2 bathroom and a separate ceramic tiled shower. Full kitchen facilities, large custom bar. There is a 3 year old 20 x 50 metal shop building with 16 ft walls which be leased for additional income. Large enough for RV storage. This would be great location for a bar, restaurant, catering business, daycare, antique store, many possibilities or could easily be converted to a private residence. There are no known restrictions to the possible uses.
Position your business for success in one of Jackson's most desirable commercial locations. This impressive 2,256 SF brick professional office building offers a polished, welcoming presence with a full, partially finished walk-out basement, providing flexibility for future expansion, storage, or additional workspace. The thoughtfully designed layout includes multiple private offices, a conference room, reception area, breakroom, and private restrooms, making it an ideal fit for medical, dental, therapy, wellness, or other professional office users. Situated in a thriving commercial corridor just off State Route D (Independence Street), this C-2 zoned property offers excellent visibility, convenient access, and a large off-street concrete parking lot for staff and clients. Surrounded by established businesses, newer residential developments, and an active community, the location is just minutes from city parks, recreational amenities, and growing neighborhoods—creating an ideal setting for serving patients, clients, or customers. Whether you're expanding an existing practice or establishing a flagship location, this property offers the professional image, accessibility, and location to help your business thrive.
Presenting a prime investment opportunity in the heart of Jackson, MO. This exceptional .799-acre commercial property, zoned C-2, boasts 150 feet of frontage on Highway 61 (I-55 Business Route) and faces a 5-lane state highway, ensuring maximum visibility in a high-traffic location. Surrounded by banks, restaurants, retail, and offices, the property offers a strategic location for a diverse range of businesses. Don't miss the chance to secure a valuable piece of real estate in this thriving commercial hub.
This property has four 4,200-square foot mini-storage buildings, totaling 118 units.
Excellent commercial opportunity in a prime location with convenient access to both Cape Girardeau and Jackson! Situated on 3.3 acres, this versatile property features a 3,800 sq ft shop building with a finished 192 sq ft office space and bathroom. The shop offers four 12x12 overhead doors, plus an attached 16x33 covered carport for additional covered workspace or storage. A rear 16x72 storage/shop area with two overhead doors provides even more flexibility, along with a spacious 24x36x13 carport/storage structure. Property also includes a security system. With ample space and excellent accessibility, this property is well suited for commercial use, future expansion, or investment potential.
This is a rare opportunity to acquire a fully equipped, high-functioning shop property just outside of Jackson along the highly trafficked Missouri Route 72. Situated on approximately 1 acre, this 5,262 SF building is purpose-built for automotive or industrial use and offers a highly efficient layout designed for workflow and productivity. The 120’ deep structure features drive-through capability with 14’ overhead doors at both ends, allowing for seamless access and movement of vehicles or equipment. Inside, the property is outfitted with valuable specialty infrastructure including a paint booth, in-floor frame rack, and an alignment rack—making it a turnkey solution for automotive repair, body shop operations, or similar users. With strong visibility, easy access, and a layout that supports high-volume operations, this property is ideal for an owner-user or investor looking for a functional, hard-to-find shop space in the Jackson market.
Check out this 5.5-acre commercial / industrial development site located on Jackson Trail in Jackson, Missouri. The property is level, padded, and ready for construction, offering a streamlined path from acquisition to vertical development. With immediate access to State Highway 25 and proximity to Jackson Boulevard, the site benefits from excellent regional connectivity. Utilities including Ameren Electric and Liberty Natural Gas are available, supporting a range of commercial and light industrial uses. Currently outside city limits but bordering the City of Jackson, this property offers valuable jurisdictional flexibility. A buyer can remain in the county or pursue annexation depending on operational needs, utility requirements, or long-term strategy. This is a strong opportunity for owner-users, developers, or investors seeking a well-located site in a growing Southeast Missouri market. This 5.5-acre tract is located on Jackson Trail in Jackson, Missouri, just off State Highway 25 and near Jackson Boulevard. The property offers strong accessibility to major traffic corridors while remaining just outside the Jackson city limits. Positioned directly adjacent to the City of Jackson boundary, the site provides a unique advantage: the flexibility to remain in the county or pursue annexation if municipal utilities, zoning, or incentives are desired. Ameren Electric and Liberty Natural Gas are available to the property, and the site has already been padded and graded, reducing development timelines. Its location within a growing commercial corridor makes it well-suited for commercial or industrial development.
Situated on Highway 61, this 3.66-acre property offers nearly 500 feet of highway frontage and is conveniently located near I-55. With public streets bordering all four sides, this versatile property enjoys high visibility and accessibility, making it suitable for a variety of businesses. Additionally, city utilities are readily available, further enhancing the property's appeal for development.
Come take a look at this prime location in Jackson! Do you need more market exposure and advertising? How about advertising on one of the most traveled roads in our area! This property has a great amount of parking, three levels, great exposure, a two bed one bath on the third level! There is so much that can be done with this property whether you are looking for a great investment, or a new office! This property is currently fully leased. Per MODOT, daily traffic count in front of this building is 10,741. Lots of exposure for your business! Location: City, High Traffic, Hwy/Interstate Frontage
Located in the beautiful city of Jackson, Missouri, this fully furnished, two-level professional office building offers a rare opportunity to own your workspace while generating income by leasing the second level. Perfectly suited for a salon, mental health counseling practice, legal office, medical use, or any professional service, this building is truly move-in ready—down to the furniture and high-end office equipment. Main Level (Ideal Owner-Occupied Space) * Welcoming reception area * 4 private offices * 2 conference rooms * Bathroom * Fully furnished, including desks, chairs, a conference table, a reception desk, bookshelves, and a high-end commercial printer Lower Level (Income-Producing or Expansion Space) * Separate private entrance * Large reception area * 4 private offices * Spacious employee breakroom * Bathroom * Laundry/storage area With excellent visibility on E. Jackson Blvd., this property is ideal for businesses seeking a professional image, easy client access, and room to grow. The Smart Play * Own your building instead of renting * Lease the upper or lower level to offset your mortgage * Use one level now and expand later * Or lease both levels for a strong investment property Whether you’re a business owner looking to stop throwing money away on rent or an investor seeking a turnkey professional building, this property delivers flexibility, functionality, and financial upside.
Prime 8-acre commercial tract located in Jackson, Missouri along County Road 307 (CR 307) with excellent visibility from I-55. This property offers strong development potential in a growing area of Cape Girardeau County with convenient access to major thoroughfares and nearby commercial corridors. The parcel features mostly level terrain with generous road frontage, allowing for flexible site planning and easy ingress and egress. Suitable for a variety of uses including retail, office, medical, light industrial, or mixed-use development. With high traffic exposure and proximity to existing infrastructure, this property presents a strong opportunity for investors and developers.
Prime location for your next Commercial Development. This 25.44 acre lot is partially cleared and ready for whatever your imagination desires. Most utilities are onsite or very nearby. It is located within 1.5 miles from I-55 Exit 102 and 1 mile from Exit 99. This is a high traffic retail area with various hotels and retail businesses nearby. Location: High Traffic, Industrial Area, Retail Center
Prime location for your next Commercial Development. This 18.76 acre lot is cleared and ready to build on. New street and all utilities are onsite. It is located within 2 miles from I-55 Exit 102 and 1 mile from Exit 99. This is a high traffic retail area with various hotels and retail businesses nearby. Location: High Traffic, Industrial Area, Retail Center
Prime location for your next Commercial or Hotel Development. This 4.17 acre lot is cleared and ready to go. New street recently poured and all utilities are onsite. It is located within 2 miles from I-55 Exit 102 and 1 mile from Exit 99. This is a high traffic retail area with various hotels and retail businesses nearby.
Prime location for your next Commercial Development. This 1.32 acre lot is cleared and ready to go. New street recently poured and all utilities are onsite. It is located within 2 miles from I-55 Exit 102 and 1 mile from Exit 99. This is a high traffic retail area with various hotels and retail businesses nearby.
Come take a look at this prime location in Jackson! Do you need more market exposure and advertising? How about advertising on one of the most traveled roads in our area! This property has a great amount of parking, three levels, great exposure, a two bed one bath on the third level! There is so much that can be done with this property whether you are looking for a great investment, or a new office! Per MODOT, daily traffic count in front of this building is 10,741. Lots of exposure for your business! Location: City, High Traffic, Hwy/Interstate Frntg
Unique and affordable buying opportunity for a discerning entrepreneur! This establishment was custom and quality built in a high traffic location, just minutes from I-55. Built in 2017 w/its maintenance free exterior and roof, the potential uses for this commercial built building are endless. Originally designed as restaurant and set up for a commercial kitchen to be installed, seating for 90 guests - this could easily become Fruitland's newest eatery. With its open floor plan and ample parking, it's perfect for a variety of dining concepts, from casual eateries to upscale fine dining. Take a minute and explore the many different possible avenues. Small church/school, retail store front, boutique style retail, private office space, professional/medical office, hair salon, daycare, day spa, vet clinic, pet grooming/boarding, insurance, attorney, local medical office... County with no zoning restrictions - this energy efficiency, easy maintenance, and gently used building is ready to get put to use! Location: High Traffic, Hwy/Interstate Frntg
Introducing a prime commercial development opportunity at 3235 E Jackson Blvd, Jackson, MO. This property is 2.97 acres brimming with potential for a restaurant operator or strip center developer. Zoned C-2, this tract offers much versatility for a variety of business uses. Adjacent to Walmart, Murphy Gas, AT&T, Jimmy John's and across from US Bank and Jackson Dental, this is a location right in the heart of expanding Jackson, MO. Don't miss the chance to secure a piece of prime ground! Location: City

Jackson is located in Missouri. Jackson, Missouri has a population of 15,272. Jackson is more family-centric than the surrounding county with 36.56% of the households containing married families with children. The county average for households married with children is 31.66%.
The median household income in Jackson, Missouri is $70,179. The median household income for the surrounding county is $59,252 compared to the national median of $69,021. The median age of people living in Jackson is 33.7 years.
The average high temperature in July is 89.5 degrees, with an average low temperature in January of 23.5 degrees. The average rainfall is approximately 49 inches per year, with 10.2 inches of snow per year.