Courtesy: RE/MAX Realty Experts
573-547-8385
Opportunity knocks in the heart of Downtown Perryville! This versatile commercial property offers approximately 1,000 square feet of prime main-level retail or professional service space, perfectly positioned in a thriving, high-visibility location. Upstairs, you’ll find an adorable, high-rated studio Airbnb that comes fully furnished and turnkey ready, complete with a full bath, mini refrigerator, microwave, and coffee station—ideal for immediate income potential. The 248 square foot space is lovingly known as June Bug’s Loft. Surrounded by popular restaurants, lively bars, local venues, and bustling small businesses, this property places you right in the center of downtown energy where community events and activities keep foot traffic strong year-round. Invest, operate, and earn—all in one incredible location.
Courtesy: Lorimont L.C.
573-334-5200
Excellent opportunity to acquire a substantial industrial property in the heart of Perryville’s manufacturing corridor. This former Seguin Moreau Cooperage site — historically utilized for stave and wood products processing — offers over 42,000± SF of functional space spread across 14 buildings on a generous 15± acre parcel with excellent highway access. This property is ideal for businesses seeking a turnkey location for light industrial manufacturing, warehouse/distribution operations, fabrication, assembly, or equipment storage. The flexible layout across multiple buildings allows for phased occupancy or sub-leasing opportunities to maximize value. Its industrial zoning and acreage also present expansion potential, additional yard space, or redevelopment concepts. Perryville, Missouri, stands as a strong industrial market within Southeast Missouri with robust transportation connectivity via Highway 61 and proximity to Interstate corridors. The region supports a diversified manufacturing base and workforce, offering tangible advantages for relocation or expansion projects. Highlights: - 42,734 SF building space with multiple structures for manufacturing, warehousing, and distribution. - 15-acre land area with I-2 zoning, suitable for a wide range of industrial uses. - Strategic location along U.S. Highway 61 for superior regional access and logistics. - Formerly used for industrial cooperage and stave production, with manufacturing yards and support buildings. - Ideal for heavy storage, fabrication, and industrial operations. - Versatile building configuration designed for manufacturing needs. - Ample indoor production space for industrial operations. - NOTE: There are working wood kilns on site and will come with the sale of the property if they are not sold before the property becomes under contract.
Courtesy: Edge Realty
573-335-8111
Opportunity to own a well known commercial property in the heart of downtown Perryville. This approximately 14,400 square foot building sits on a large lot and is currently tenant occupied by The Alley Cat Lanes and Lounge, providing an established presence and built in income potential. The property offers excellent visibility, ample space, and a prime location surrounded by local businesses, dining, and community activity. Ideal for investors or buyers seeking a sizeable commercial footprint with an existing tenant in place.
Courtesy: Edge Realty
573-335-8111
Rare opportunity to acquire a multi tenant, mixed use property totaling over 20,000 square feet, ideally located on the square in downtown Perryville. This beautifully designed property features eight residential units, with a mix of short term rentals currently operating as Airbnbs and long term residential leases, offering diversified income streams. The property also includes four fully leased commercial units that have seen extensive improvements, including major structural updates such as electrical and HVAC systems, providing peace of mind for future ownership. Positioned in a prime downtown location with strong visibility and consistent tenancy, this is an exceptional investment opportunity with established cash flow and long term upside.
Courtesy: Edge Realty
573-335-8111
Looking for a turn key, fully operational business in the heart of Perryville? The Mediterranean House presents a rare opportunity to own a luxury property designed to host unforgettable stays and events. Currently operating as a successful and versatile venue, this property is well suited for use as an Airbnb, bed and breakfast, or a destination for corporate retreats, wellness or yoga getaways, and private events. The home features six beautifully appointed bedrooms, four full bathrooms, and one half bathroom, offering ample accommodations for guests. A commercial grade kitchen equipped with stainless steel appliances is ready to support culinary experiences, from baking and cooking workshops to catered events. All furniture stays, including antique furnishings, bedroom suites, dining room suites, etc. With its flexible layout and elegant setting, The Mediterranean House is ideal for bridal and baby showers, birthday celebrations, intimate gatherings, or larger hosted events. This is a truly turn key business opportunity, ready for immediate operation, offering the space, functionality, and charm to bring a wide range of visions to life.
Courtesy: 573 Realty Group
573-547-1000
Position your business for success with this exceptional C-2 zoned 2.26-acre property offering highway frontage, strong visibility, and steady traffic flow along the Highway 51 corridor. Located in an area experiencing recent development, this site is well-positioned for continued commercial growth and accommodates a wide range of potential uses. The property includes a 1,727 sq ft, 3-bedroom home with a full basement, providing flexibility for owner occupancy, office conversion, or on-site operational space during future development. Also included is a 30x56 fully insulated metal outbuilding, constructed in 2018 by Ponder Built, featuring 12-foot ceilings, insulated overhead doors, concrete floor, metal-lined interior, bathroom with slop sink and toilet, permanent automotive lift, air compressor with plumbed air lines, and 3.5-ton HVAC unit with dehumidifier for year-round climate control. This building is potentially suited for a variety of commercial operations. An existing billboard lease adds additional income potential. With its strong exposure, zoning, and versatile improvements, this property offers an outstanding opportunity for investors, developers, or owner-users seeking a high-visibility commercial site along a proven corridor. Duplicate listing 25080826
Courtesy: AgriBuck Properties
573-513-5701
Historic Commercial Gem on the Square – 1859 Brick Building, Fully Restored & Modernized Step into a piece of local history! Built in 1859 as the first brick building on the square, this remarkable commercial property beautifully blends timeless character with complete modern functionality. Every inch of this building has been thoughtfully updated while preserving its historic charm. Property Highlights: Fully replumbed, rewired, and reroofed — truly turnkey and up to code HVAC system updated with central air, plus mini-splits for added comfort and efficiency All new windows and complete tuckpointing inside and out for long-term durability Trim lighting around the roof adds modern curb appeal to the historic façade Water softening system is owned and professionally maintained through a service program Additional lot space with direct access off S. Jackson Street—ample room for constructing an additional building, expansion, or added parking options Currently houses three separate office spaces, an operating salon, and three Airbnb units on the upper level—providing immediate income potential Interior Features: Welcoming reception and waiting areas ideal for client interaction Multiple private offices and break rooms for staff comfort and productivity Functional layout suitable for professional offices, retail, hospitality, or mixed use This building stands as a cornerstone of history—the first brick structure on the square—but offers the peace of mind of a fully updated, code-compliant property. With existing income-generating spaces and bonus expansion potential on the adjoining lot, it’s perfect for buyers who value historic charm, modern reliability, and room to grow.
Courtesy: RE/MAX Realty Experts
573-547-8385
Day Care Building for Sale – Turnkey Opportunity! Looking to own your own day care or expand your childcare business? This ready-to-go day care facility offers everything you need to get started right away! Property Highlights: 1,344 sq. ft. main level designed for day care use; 3 bathrooms for convenience and compliance; Kitchen area plus dining space for meal and snack times; All day care contents included (if buyer continues to use as a day care); Appliances included: stove and 2 refrigerators, microwave; Large fenced playground area – safe and perfect for outdoor fun; Unfinished lower level provides room for storage or future expansion; Small shed included for extra storage; Updated HVAC system plus 2 window A/C units for year-round comfort. This property is move-in ready for your day care business — everything you need is already in place! Whether you’re an experienced provider or starting a new venture, this is a rare opportunity to own a fully equipped child care facility.
Courtesy: RE/MAX Realty Experts
573-547-8385
4040 +/- SF Downtown Perryville Commercial Building – Fantastic investment opportunity! This prime corner-lot property features 4 rentable units with excellent income-generating potential. The building includes a full 4040 +/- sq. ft. walk-out basement, perfect for storage, expansion, or conversion into additional rental space for added income. With high street visibility and convenient street parking plus extra parking at the basement level, this property offers great accessibility. Ideal for professional offices, boutique retail, or mixed-use tenants, it provides flexibility for a variety of business opportunities. Don’t miss this chance to secure a solid income property in a high-traffic downtown location!
Courtesy: AgriBuck Properties
573-513-5701
Prime Commercial Opportunity on Highway 61 – Perryville, MO Seize the chance to own a commercial property with outstanding potential along the highly traveled Highway 61 in Perryville. This vacant building is being sold as-is, offering a blank slate to bring your business vision to life. With excellent highway frontage and visibility, the property ensures maximum exposure for future customers. Whether you’re looking to establish retail, office space, service business, or invest for future development, this location offers versatility and opportunity. Don’t miss out on this affordable entry into a high-traffic commercial corridor—schedule a showing today and imagine the possibilities!
Courtesy: Re/max Realty Experts
573-547-8385
Motivated Seller says Make Reasonable Offer! Are you looking for a new location that has a ton of daily traffic to further promote your business? This property is located on the corner of State Highway 61 and Highway E, providing an AADT count of 4,085 daily passersby in 2023. The building offers 1488 sf of space which is currently utilized as a completely remodeled office space with a warehouse and full bathroom. The property has undergone significant updates including a metal roof, wiring and plumbing as well as all new insulation, gutters and much more. This building has potential for so many uses with the ability for expansion into the warehouse area. Let your dreams take shape with this affordable investment! Location: City, Corner Location, High Traffic
Courtesy: Land Xchange Inc
636-797-8257
Great laying property located just off Highway 55 with highway visibility, land lays incredibly flat and is zoned C-2 which offers a wide variety of uses, from a restaurant, hotel, Apartments, and far to many more to list. Under the C-2 zoning the C-1 is also in play with many other types of uses. There is already a water easement in place on the South end of the property and a couple of options to bring in sewer. There is a small cut out of the property with 2 billboards that is not part of the property, but does have a smaller billboard sold with the property. If you are looking to expand an existing business or a new start up company this is a great opportunity in a fast growing area. Location: City, High Traffic, Hwy/Interstate Frntg
Courtesy: Re/max Realty Experts
573-547-8385
Excellent .94 acre commercial development potential. Easy access to both I-55 and the vibrant downtown of Perryville. Great location in a high traffic area and makes a nice site for any type of business including restaurant, office, or retail. 180 feet of road frontage. Nearby businesses include: Walgreens, Scooter’s Coffee, Midwest Total Urgent Care, and Perryville Tire. Value-added site improvements have already been completed to bring this tract to a ready standard for any build-to-suit or custom prospect. Appropriate ingress / egress access. The property is zoned C-2 in a strategic location prime for new development with easy access to major thoroughfares. The current business in this property in not closed and will remain in business for one year from sale date. Location: City, Corner Location, High Traffic, Hwy/Interstate Frntg
Courtesy: Lorimont L.c.
573-334-5200
23.86 acre corner lot ready for development in growing area of Perryville with excellent traffic and visibility. Suitable for various uses. Close to industrial businesses. Currently not in the city limits, but city utilities are nearby for easy annexation. Location: Corner Location, Hwy/Interstate Frntg, Industrial Park, Industrial Area
Courtesy: Lorimont L.c.
573-334-5200
9.45 acres ready for development near Missouri's National Veterans Memorial. Suitable for various uses. City utilities nearby and close to industrial businesses. Location: Hwy/Interstate Frntg, Rural
Courtesy: Lorimont L.c.
573-334-5200
3.7 acre corner lot ready for development in north end of Perryville with excellent traffic and visibility on Highway 51. Suitable for various uses. Currently not in the city limits, but city utilities are nearby for easy annexation. Location: Corner Location, Hwy/Interstate Frntg
Courtesy: Lorimont L.c.
573-334-5200
2.39 acre corner lot ready for development in north end of Perryville with excellent traffic and visibility at the intersection of Highway 51 and N. Main St. Suitable for various uses. Perfect for C-store. Currently not in the city limits, but city utilities are nearby for easy annexation. Location: Corner Location, Hwy/Interstate Frntg
Courtesy: 573 Realty Group
573-547-1000
Check out this subdivision already established with utilities, sidewalks, street lights, streets, and restrictions. 15 lots remain and are already platted. This is a great opportunity to develop or sell lots individually for the next buyer to build to their liking. With this being the only subdivision offering lots, the possibilities are endless. Four homes have already been built and sold. The demand for housing in Perry County makes this a no brainer. Location: City
Courtesy: 573 Realty Group
573-547-1000
Seize this exceptional commercial property in a high visibility location, just blocks from downtown and directly across from the newly built Justice Center. This property features a spacious reception area, supply room, full kitchen, 1.5 bathrooms, a file room and 7 private offices. Additionally, there is an income generating opportunity with three vacant rental spaces you could maximize revenue. With three separate exterior entrances, the space offers flexibility for multiple tenants or business uses. The existing carport could also be enclosed for additional storage. Looking for something different? Take advantage of the C-2 zoning and prime location to customize build your ideal business venture. Whether you're expanding, relocating, or investing, this property offers endless possibilities on the corner with over 300' of road frontage. Currently generating monthly income through leases. Location: City, Corner Location, Downtown, High Traffic
Courtesy: Land XChange Inc
636-797-8257
Great laying property located just off Highway 55 with highway visibility, land lays incredibly flat and is zoned C-2 which offers a wide variety of uses, from a restaurant, hotel, Apartments, and far to many more to list. Under the C-2 zoning the C-1 is also in play with many other types of uses. There is already a water easement in place on the South end of the property and a couple of options to bring in sewer. There is a small cut out of the property with 2 billboards that is not part of the property, but does have a smaller billboard sold with the property. If you are looking to expand an existing business or a new start up company this is a great opportunity in a fast growing area. Location: City, High Traffic, Hwy/Interstate Frntg
Courtesy: RE/MAX Realty Experts
573-547-8385
Excellent .94 acre commercial development potential. Easy access to both I-55 and the vibrant downtown of Perryville. Great location in a high traffic area and makes a nice site for any type of business including restaurant, office, or retail. 180 feet of road frontage. Nearby businesses include: Walgreens, Scooter’s Coffee, Duke Veterinary Clinic, and Perryville Tire. Value-added site improvements have already been completed to bring this tract to a ready standard for any build-to-suit or custom prospect. Appropriate ingress / egress access. The property is zoned C-2 in a strategic location prime for new development with easy access to major thoroughfares. The current business in this property in not closed and will remain in business for one year from sale date. Location: City, Corner Location, High Traffic, Hwy/Interstate frontage.
Courtesy: Lorimont L.C.
573-334-5200
23.86 acre corner lot ready for development in growing area of Perryville with excellent traffic and visibility. Suitable for various uses. Close to industrial businesses. Currently not in the city limits, but city utilities are nearby for easy annexation. Location: Corner Location, Hwy/Interstate Frntg, Industrial Park, Industrial Area
Courtesy: Lorimont L.C.
573-334-5200
9.45 acres ready for development near Missouri's National Veterans Memorial. Suitable for various uses. City utilities nearby and close to industrial businesses. Location: Hwy/Interstate Frntg, Rural
Courtesy: Lorimont L.C.
573-334-5200
3.7 acre corner lot ready for development in north end of Perryville with excellent traffic and visibility on Highway 51. Suitable for various uses. Currently not in the city limits, but city utilities are nearby for easy annexation. Location: Corner Location, Hwy/Interstate Frntg
Courtesy: Lorimont L.C.
573-334-5200
2.39 acre corner lot ready for development in north end of Perryville with excellent traffic and visibility at the intersection of Highway 51 and N. Main St. Suitable for various uses. Perfect for C-store. Currently not in the city limits, but city utilities are nearby for easy annexation. Location: Corner Location, Hwy/Interstate Frntg
Perryville is located in Missouri. Perryville, Missouri has a population of 8,482. Perryville is less family-centric than the surrounding county with 30.51% of the households containing married families with children. The county average for households married with children is 32.72%.
The median household income in Perryville, Missouri is $50,774. The median household income for the surrounding county is $56,832 compared to the national median of $69,021. The median age of people living in Perryville is 38.2 years.
The average high temperature in July is 89.1 degrees, with an average low temperature in January of 21.7 degrees. The average rainfall is approximately 44 inches per year, with 7.3 inches of snow per year.
