Courtesy: Edge Realty
573-335-8111
Opportunity to own a well known commercial property in the heart of downtown Perryville. This approximately 14,400 square foot building sits on a large lot and is currently tenant occupied by The Alley Cat Lanes and Lounge, providing an established presence and built in income potential. The property offers excellent visibility, ample space, and a prime location surrounded by local businesses, dining, and community activity. Ideal for investors or buyers seeking a sizeable commercial footprint with an existing tenant in place.
Courtesy: Edge Realty
573-335-8111
Rare opportunity to acquire a multi tenant, mixed use property totaling over 20,000 square feet, ideally located on the square in downtown Perryville. This beautifully designed property features eight residential units, with a mix of short term rentals currently operating as Airbnbs and long term residential leases, offering diversified income streams. The property also includes four fully leased commercial units that have seen extensive improvements, including major structural updates such as electrical and HVAC systems, providing peace of mind for future ownership. Positioned in a prime downtown location with strong visibility and consistent tenancy, this is an exceptional investment opportunity with established cash flow and long term upside.
Courtesy: Edge Realty
573-335-8111
Looking for a turn key, fully operational business in the heart of Perryville? The Mediterranean House presents a rare opportunity to own a luxury property designed to host unforgettable stays and events. Currently operating as a successful and versatile venue, this property is well suited for use as an Airbnb, bed and breakfast, or a destination for corporate retreats, wellness or yoga getaways, and private events. The home features six beautifully appointed bedrooms, four full bathrooms, and one half bathroom, offering ample accommodations for guests. A commercial grade kitchen equipped with stainless steel appliances is ready to support culinary experiences, from baking and cooking workshops to catered events. All furniture stays, including antique furnishings, bedroom suites, dining room suites, etc. With its flexible layout and elegant setting, The Mediterranean House is ideal for bridal and baby showers, birthday celebrations, intimate gatherings, or larger hosted events. This is a truly turn key business opportunity, ready for immediate operation, offering the space, functionality, and charm to bring a wide range of visions to life.
Courtesy: 573 Realty Group
573-547-1000
Position your business for success with this exceptional C-2 zoned 2.26-acre property offering highway frontage, strong visibility, and steady traffic flow along the Highway 51 corridor. Located in an area experiencing recent development, this site is well-positioned for continued commercial growth and accommodates a wide range of potential uses. The property includes a 1,727 sq ft, 3-bedroom home with a full basement, providing flexibility for owner occupancy, office conversion, or on-site operational space during future development. Also included is a 30x56 fully insulated metal outbuilding, constructed in 2018 by Ponder Built, featuring 12-foot ceilings, insulated overhead doors, concrete floor, metal-lined interior, bathroom with slop sink and toilet, permanent automotive lift, air compressor with plumbed air lines, and 3.5-ton HVAC unit with dehumidifier for year-round climate control. This building is potentially suited for a variety of commercial operations. An existing billboard lease adds additional income potential. With its strong exposure, zoning, and versatile improvements, this property offers an outstanding opportunity for investors, developers, or owner-users seeking a high-visibility commercial site along a proven corridor. Duplicate listing 25080826
Courtesy: AgriBuck Properties
573-513-5701
Historic Commercial Gem on the Square – 1859 Brick Building, Fully Restored & Modernized Step into a piece of local history! Built in 1859 as the first brick building on the square, this remarkable commercial property beautifully blends timeless character with complete modern functionality. Every inch of this building has been thoughtfully updated while preserving its historic charm. Property Highlights: Fully replumbed, rewired, and reroofed — truly turnkey and up to code HVAC system updated with central air, plus mini-splits for added comfort and efficiency All new windows and complete tuckpointing inside and out for long-term durability Trim lighting around the roof adds modern curb appeal to the historic façade Water softening system is owned and professionally maintained through a service program Additional lot space with direct access off S. Jackson Street—ample room for constructing an additional building, expansion, or added parking options Currently houses three separate office spaces, an operating salon, and three Airbnb units on the upper level—providing immediate income potential Interior Features: Welcoming reception and waiting areas ideal for client interaction Multiple private offices and break rooms for staff comfort and productivity Functional layout suitable for professional offices, retail, hospitality, or mixed use This building stands as a cornerstone of history—the first brick structure on the square—but offers the peace of mind of a fully updated, code-compliant property. With existing income-generating spaces and bonus expansion potential on the adjoining lot, it’s perfect for buyers who value historic charm, modern reliability, and room to grow.
Courtesy: RE/MAX Realty Experts
573-547-8385
Day Care Building for Sale – Turnkey Opportunity! Looking to own your own day care or expand your childcare business? This ready-to-go day care facility offers everything you need to get started right away! Property Highlights: 1,344 sq. ft. main level designed for day care use; 3 bathrooms for convenience and compliance; Kitchen area plus dining space for meal and snack times; All day care contents included (if buyer continues to use as a day care); Appliances included: stove and 2 refrigerators, microwave; Large fenced playground area – safe and perfect for outdoor fun; Unfinished lower level provides room for storage or future expansion; Small shed included for extra storage; Updated HVAC system plus 2 window A/C units for year-round comfort. This property is move-in ready for your day care business — everything you need is already in place! Whether you’re an experienced provider or starting a new venture, this is a rare opportunity to own a fully equipped child care facility.
Courtesy: Keller Williams Realty St. Louis
314-677-6000
A Perfect Retreat, Venue or Bed & Breakfast opportunity! Discover unmatched craftsmanship & comfort in this custom full-brick ranch, offering over 6,000 sq ft of total living space surrounded by 5 serene acres (10 add'l acres negotiable). Main level offers 10-ft ceilings–some vaulted, Pella windows, solid-core decorative wood with transoms, custom red oak cabinetry & built in bookcases/shelving (all reclaimed from a historic high school chemistry lab), pantry, main floor laundry, spacious dining area, breakfast room & 8-person breakfast bar. Features 4 BRs (4th w/o closet, armoires stay), 3 full baths, plus add’l lower-level bathroom & laundry rough-in. With potential for two kitchens making it ideal for commercial style appliances & prep space. Main-level gas fireplace & lower-level wood-burning fireplace/furnace for added heat source. Oversized, tandem 4-car garage - heated/cooled/220 electric. 4 HVAC units - new high-efficiency gas furnace (2023) & geothermal, 800-ft well (new pump 2021), central vac, attic fan, hot tub-ready hookup, stocked shared pond & circle drive. Currently furnished with many historic items - some may stay if buyer chooses. There is so much more, too numerous to mention - additional details available upon request. This beautiful home is in a peaceful rural setting close to both Chester IL & Perryville MO, that blends luxury finishes & energy efficiency. With room for parking, outdoor structures & great photo opportunities - bring your ideas & plans!
Courtesy: RE/MAX Realty Experts
573-547-8385
4040 +/- SF Downtown Perryville Commercial Building – Fantastic investment opportunity! This prime corner-lot property features 4 rentable units with excellent income-generating potential. The building includes a full 4040 +/- sq. ft. walk-out basement, perfect for storage, expansion, or conversion into additional rental space for added income. With high street visibility and convenient street parking plus extra parking at the basement level, this property offers great accessibility. Ideal for professional offices, boutique retail, or mixed-use tenants, it provides flexibility for a variety of business opportunities. Don’t miss this chance to secure a solid income property in a high-traffic downtown location!
Courtesy: RE/MAX Realty Experts
573-547-8385
Prime development opportunity in a highly visible location! This 11.46-acre property offers highway frontage with excellent visibility from the interstate, ensuring maximum exposure for your project. The groundwork has already been started with dirt work completed, and city utilities are available on-site and ready to be connected to, making it easier and faster to bring your vision to life. Whether you’re considering multi-story apartments, a residential subdivision, duplexes, or other investment opportunities, this property provides endless potential. With its unbeatable location and development-ready condition, it’s the perfect spot to turn your plans into reality!
Courtesy: AgriBuck Properties
573-513-5701
Prime Commercial Opportunity on Highway 61 – Perryville, MO Seize the chance to own a commercial property with outstanding potential along the highly traveled Highway 61 in Perryville. This vacant building is being sold as-is, offering a blank slate to bring your business vision to life. With excellent highway frontage and visibility, the property ensures maximum exposure for future customers. Whether you’re looking to establish retail, office space, service business, or invest for future development, this location offers versatility and opportunity. Don’t miss out on this affordable entry into a high-traffic commercial corridor—schedule a showing today and imagine the possibilities!
Courtesy: RE/MAX Realty Experts
573-547-8385
Built in 1879, this all brick building was more recently converted into a successful, shared office space concept known as Avanti East. The building houses five separate offices that generate rental income. There is also a shared meeting room or workspace that can generate additional revenue. The main level also offers a kitchenette and restroom. The building has charming curb appeal with professional landscaping and signage for tenants. Parking is plentiful in nearby City parking lot. This charming building is located in the flourishing downtown area. Some equipment, furniture and business amenities are included in the purchase of this turn-key opportunity. Own a piece of history today with this beautiful building.
Courtesy: Re/max Realty Experts
573-547-8385
Motivated Seller says Make Reasonable Offer! Are you looking for a new location that has a ton of daily traffic to further promote your business? This property is located on the corner of State Highway 61 and Highway E, providing an AADT count of 4,085 daily passersby in 2023. The building offers 1488 sf of space which is currently utilized as a completely remodeled office space with a warehouse and full bathroom. The property has undergone significant updates including a metal roof, wiring and plumbing as well as all new insulation, gutters and much more. This building has potential for so many uses with the ability for expansion into the warehouse area. Let your dreams take shape with this affordable investment! Location: City, Corner Location, High Traffic
Courtesy: Land Xchange Inc
636-797-8257
Great laying property located just off Highway 55 with highway visibility, land lays incredibly flat and is zoned C-2 which offers a wide variety of uses, from a restaurant, hotel, Apartments, and far to many more to list. Under the C-2 zoning the C-1 is also in play with many other types of uses. There is already a water easement in place on the South end of the property and a couple of options to bring in sewer. There is a small cut out of the property with 2 billboards that is not part of the property, but does have a smaller billboard sold with the property. If you are looking to expand an existing business or a new start up company this is a great opportunity in a fast growing area. Location: City, High Traffic, Hwy/Interstate Frntg
Courtesy: Re/max Realty Experts
573-547-8385
Excellent .94 acre commercial development potential. Easy access to both I-55 and the vibrant downtown of Perryville. Great location in a high traffic area and makes a nice site for any type of business including restaurant, office, or retail. 180 feet of road frontage. Nearby businesses include: Walgreens, Scooter’s Coffee, Midwest Total Urgent Care, and Perryville Tire. Value-added site improvements have already been completed to bring this tract to a ready standard for any build-to-suit or custom prospect. Appropriate ingress / egress access. The property is zoned C-2 in a strategic location prime for new development with easy access to major thoroughfares. The current business in this property in not closed and will remain in business for one year from sale date. Location: City, Corner Location, High Traffic, Hwy/Interstate Frntg
Courtesy: Lorimont L.c.
573-334-5200
23.86 acre corner lot ready for development in growing area of Perryville with excellent traffic and visibility. Suitable for various uses. Close to industrial businesses. Currently not in the city limits, but city utilities are nearby for easy annexation. Location: Corner Location, Hwy/Interstate Frntg, Industrial Park, Industrial Area
Courtesy: Lorimont L.c.
573-334-5200
9.45 acres ready for development near Missouri's National Veterans Memorial. Suitable for various uses. City utilities nearby and close to industrial businesses. Location: Hwy/Interstate Frntg, Rural
Courtesy: Lorimont L.c.
573-334-5200
3.7 acre corner lot ready for development in north end of Perryville with excellent traffic and visibility on Highway 51. Suitable for various uses. Currently not in the city limits, but city utilities are nearby for easy annexation. Location: Corner Location, Hwy/Interstate Frntg
Courtesy: Lorimont L.c.
573-334-5200
2.39 acre corner lot ready for development in north end of Perryville with excellent traffic and visibility at the intersection of Highway 51 and N. Main St. Suitable for various uses. Perfect for C-store. Currently not in the city limits, but city utilities are nearby for easy annexation. Location: Corner Location, Hwy/Interstate Frntg
Courtesy: 573 Realty Group
573-547-1000
Check out this subdivision already established with utilities, sidewalks, street lights, streets, and restrictions. 15 lots remain and are already platted. This is a great opportunity to develop or sell lots individually for the next buyer to build to their liking. With this being the only subdivision offering lots, the possibilities are endless. Four homes have already been built and sold. The demand for housing in Perry County makes this a no brainer. Location: City
Courtesy: RE/MAX Realty Experts
573-547-8385
Unique rural commercial opportunity conveniently located between Perryville & Fredericktown and situated on 13.5+/- acres! This expansive 6,000 sq ft building offers incredible versatility for a wide range of ventures. Imagine the possibilities in this peaceful setting with ample space to customize your needs. Offering two large, finished office/recreation spaces with amazing views, two restrooms & a large warehouse with a loft, overhead doors, and a dock. Perfect for artisan workshops, manufacturing, event venue, storage/distribution or personalize the space for your future dream home! Explore the potential today! Final acreage amount is subject to a survey. Land is being divided off a larger tract. Location: Rural
Courtesy: 573 Realty Group
573-547-1000
Seize this exceptional commercial property in a high visibility location, just blocks from downtown and directly across from the newly built Justice Center. This property features a spacious reception area, supply room, full kitchen, 1.5 bathrooms, a file room and 7 private offices. Additionally, there is an income generating opportunity with three vacant rental spaces you could maximize revenue. With three separate exterior entrances, the space offers flexibility for multiple tenants or business uses. The existing carport could also be enclosed for additional storage. Looking for something different? Take advantage of the C-2 zoning and prime location to customize build your ideal business venture. Whether you're expanding, relocating, or investing, this property offers endless possibilities on the corner with over 300' of road frontage. Currently generating monthly income through leases. Location: City, Corner Location, Downtown, High Traffic
Courtesy: Landmark Real Estate Group Residential
314-965-9110
Looking for a turn-key, fully operational business in a prime location? The Mediterranean House offers an extraordinary opportunity to own a luxury property that serves as a versatile venue for a variety of events and stays. Whether you’re interested in an Airbnb, bed and breakfast, corporate or wellness/yoga retreats, this stunning property is the perfect setting to create memorable experiences. Key features include 6 beautifully appointed BR's, 3 full BA's & 2 half BA's. Commercial-grade kitchen with stainless steel appliances ready for culinary excellence. Perfect for baking/cooking workshops, bridal/baby showers, birthday parties, and more! This functional, turn-key business is ready for immediate operation, with bookings through September 2025! Whether you're looking to host small gatherings or large celebrations, this property offers the space, luxury, and flexibility to accommodate it all. This is a duplicate listing, please reference MLS#24070248. Location: Downtown, High Traffic
Courtesy: Land XChange Inc
636-797-8257
Great laying property located just off Highway 55 with highway visibility, land lays incredibly flat and is zoned C-2 which offers a wide variety of uses, from a restaurant, hotel, Apartments, and far to many more to list. Under the C-2 zoning the C-1 is also in play with many other types of uses. There is already a water easement in place on the South end of the property and a couple of options to bring in sewer. There is a small cut out of the property with 2 billboards that is not part of the property, but does have a smaller billboard sold with the property. If you are looking to expand an existing business or a new start up company this is a great opportunity in a fast growing area. Location: City, High Traffic, Hwy/Interstate Frntg
Courtesy: RE/MAX Realty Experts
573-547-8385
Excellent .94 acre commercial development potential. Easy access to both I-55 and the vibrant downtown of Perryville. Great location in a high traffic area and makes a nice site for any type of business including restaurant, office, or retail. 180 feet of road frontage. Nearby businesses include: Walgreens, Scooter’s Coffee, Duke Veterinary Clinic, and Perryville Tire. Value-added site improvements have already been completed to bring this tract to a ready standard for any build-to-suit or custom prospect. Appropriate ingress / egress access. The property is zoned C-2 in a strategic location prime for new development with easy access to major thoroughfares. The current business in this property in not closed and will remain in business for one year from sale date. Location: City, Corner Location, High Traffic, Hwy/Interstate frontage.
Courtesy: Lorimont L.C.
573-334-5200
23.86 acre corner lot ready for development in growing area of Perryville with excellent traffic and visibility. Suitable for various uses. Close to industrial businesses. Currently not in the city limits, but city utilities are nearby for easy annexation. Location: Corner Location, Hwy/Interstate Frntg, Industrial Park, Industrial Area
Perryville is located in Missouri. Perryville, Missouri has a population of 8,482. Perryville is less family-centric than the surrounding county with 30.51% of the households containing married families with children. The county average for households married with children is 32.72%.
The median household income in Perryville, Missouri is $50,774. The median household income for the surrounding county is $56,832 compared to the national median of $69,021. The median age of people living in Perryville is 38.2 years.
The average high temperature in July is 89.1 degrees, with an average low temperature in January of 21.7 degrees. The average rainfall is approximately 44 inches per year, with 7.3 inches of snow per year.
