Courtesy: Edge Realty
573-620-6054
Prime commercial investment opportunity in a high-traffic location near Future I-57/Hwy 60, I-55, and major shopping destinations. This property is currently occupied by an established restaurant tenant, providing immediate income for the new owner with long-term potential for continued restaurant use or future development. Excellent visibility and easy access make this an ideal asset for investors seeking a stable, income-producing property in a growing community. The building offers 2,275 SF, along with 4,800 SF of concrete parking and 7,800 SF of additional gravel parking.
Courtesy: Century 21 Ashland Realty
573-334-2121
Take a look at this Historical Property with modern flair situated in a prime downtown location. Enduring style and sophistication grace this beautiful 2 story, historic gem in the heart of downtown Sikeston. This is a rare and affordable buying opportunity for an investor or business owner looking for a high-visibility location with abundance of parking. Originally built in 1915, this historic building is a notorious staple of Sikeston. The stately high ceilings adorn both levels, and the ideas and uses are limited only to a ones imagination. Most recent uses were an art studio, photography studio, and retail coffee shop.
Courtesy: Preferred Realty
573-768-3770
This first of two turnkey carwashes is strategically located in Sikeston, MO, benefiting from high traffic counts and excellent visibility. Built in 2016, the property features two bays, one tunnel and one touchless along with vacuum cleaners and updated equipment. An established monthly membership program provides recurring revenue and operational stability. A major highlight of this offering is the vast amount of road frontage which allows excellent visibility and strong traffic exposure. Must sell with MLS 26000081 as a combined portfolio sale, providing a rare opportunity to control multiple wash formats within a one-mile radius. This great commercial property offering is well-suited for both owner-operators looking to establish a dominant local presence and investors seeking a stabilized asset with upside in a growing regional market.
Courtesy: Preferred Realty
573-768-3770
This second of two carwashes consists of 5 bays-3 self-serves and 2 automatic which offers a complementary operation within the same high-demand market. Built in 2015, and benefits from excellent visibility and strong traffic exposure. As a turnkey setup, with all new equipment, this location provides a lower-overhead operation that pairs well with the tunnel facility, capturing a broader customer base and reinforcing brand presence within the trade area. An established monthly membership program provides recurring revenue and operational stability. A major highlight of this property is the additional land which allows for significant expansion or redevelopment potential. The additional land allows for the opportunity to extend wash operations, add complementary services, or pursue an additional commercial use, enhancing long-term value. Great commercial property for an investor looking to add to their portfolio for scalable growth in a proven market. This offering is well-suited for both owner-operators looking to establish a dominant local presence and investors seeking a stabilized asset with upside in a growing regional market. Must be sold with MLS 26000082 as a package.
Courtesy: Century 21 Premiere Realty
573-472-2411
For over 20 years, this location has been home to a successful fast-food restaurant, proving its long-term viability and premium placement. With outstanding traffic counts on a signaled intersection, the property is ideal for QSR or redevelopment into a high-demand commercial use. Highlights: · Zoned C3 Highway Commercial · 1.2 acres in a prime commercial zone · 43 parking spaces with current layout · 471’ of highway frontage, located on the city’s busiest thoroughfare · High-visibility 4-way stoplight intersection · Outstanding traffic count and accessibility · Proven location with 20+ years of established business history · Nearby businesses include Lowe’s Home Improvement, Wal Mart, Taco Bell, Starbucks, Applebee’s, Hampton Inn, Holiday Inn, and Fairfield Inn and Suites. · Over 3600 square foot existing building with drive through
Courtesy: Century 21 Premiere Realty
573-472-2411
Large warehouse space with easy access to I-55 and I-57. The space is easily separated into two units if desired. The front space is 20,000 square feet with columns in the middle and 25' bays. 18' ceiling height and concrete floor. 2 bathrooms. 2 loading docks plus 1 overhead door. The back unit is almost 5,000 square feet and contains a shop area with 3 offices, 3 bathrooms and a lockable storage area. 2 12x14 overhead doors.
Courtesy: Edge Realty
573-335-8111
Multi tenant income producing property with leased commercial spaces and 35 storage units.
Courtesy: Century 21 Premiere Realty
573-472-2411
INVESTORS ALERT?? If you are looking to add to your investments or want to start, this is this perfect opportunity. This four plex townhouse with its new roof December 2025, unit 718 with a total makeover completed January 2026 and 3 long time tenants makes this commercial property a want to see and idea to those ready to invest. Parking on both sides of building and each unit has its own private patio. That’s not all! A partial basement with extra storage and a coin operated washer/dryer giving additional income making this property more inviting. What a good way to start off 2026 making this yours.
Courtesy: Edge Realty
573-335-8111
Prime commercial opportunity with unbeatable I-55 frontage and visibility! Sitting on 8+ acres, this property combines location, space and accessibility-making it ideal for a wide range of industrial, logistics, or distribution operations. 10,000+ sq ft under roof industrial warehouse. Multiple overhead doors for seamless loading/unloading. Easy access for trucks, trailers, and heavy equipment. The interior is in solid condition and ready for immediate use. Expansive acreage allows for yard storage, parking or future expansion. Whether you're looking to expand your current business, relocate to a high-traffic corridor, or invest in a versatile industrial property, this site checks all the boxes. Conveniently located right off I-55 with direct frontage and high visibility-your operations (and signage) won't go unnoticed.
Courtesy: Century 21 Premiere Realty
573-472-2411
Commercial property in downtown Sikeston, 202 S Kingshighway is ready to be sold. Building was last use as a Missouri State Unemployed Office and has a gross building area of 7,638 sq ft. Property sits on a corner lot, has 15 parking places (2 handicap), handicap ramp at front entrance and a back entrance from parking lot. On the main level, you will find a receptionist area, large open space with several office cubicles (easily removed if not needed), two separate offices and 2 restrooms. Located near the reception area there is a set of stairs leading to the basement. When entering the back entrance, there’s a set of stairs and an elevator that lead to the basement. Here’s where you will find the kitchen break room area, 2 restrooms, large conference room or office, storage and a spacious open area for cubicles if needed. With the layout, location and square footage this property offers, making it endless purposes and business opportunities.
Courtesy: Lorimont L.C.
573-334-5200
Discover an exceptional investment opportunity at this prime property located in the sought-after Sikeston area. Boasting a strategic location off Future Interstate 57, this property offers a unique proposition for industrial investors. With ample acreage and convenient access to major transportation routes, the potential for development is unmatched. The property's proximity to thriving businesses and distribution hubs makes it an ideal choice for those seeking a strategic industrial location. Don't miss the chance to capitalize on this promising investment in the dynamic Sikeston area.
Courtesy: Lorimont L.C.
573-334-5200
Located on Larcel Dive in Sikeston, Missouri, this industrial lot has easy access to Future Interstate 57 and minutes from the intersection of Interstates 55 and 57. Situated on a generous lot, this property offers extensive space ideal for industrial and commercial endeavors. Its strategic location in the Sikeston area provides a prime opportunity for businesses seeking to establish a strong presence in a thriving industrial and commercial hub. With its close proximity to major transportation routes and exceptional visibility, the property ensures optimal accessibility and exposure. The expansive lot not only allows for immediate utilization but also provides room for future expansion and customization, making it an attractive prospect for investors looking to capitalize on industrial and commercial growth opportunities.
Courtesy: Lorimont L.C.
573-334-5200
Located on Larcel Dive in Sikeston, Missouri, this industrial lot has easy access to Future Interstate 57 and minutes from the intersection of Interstates 55 and 57. The property boasts a spacious lot that provides ample room for industrial and commercial development. In addition to its generous lot size and strategic location, this prime property offers exceptional visibility from the future Interstate 57, further enhancing its appeal to potential investors. The future Interstate 57 visibility ensures that the property will benefit from increased exposure and accessibility, making it a highly desirable investment opportunity for those seeking to capitalize on the anticipated growth and development in the area. With its generous size, this lot offers a wide range of possibilities for expansion, construction, and customization. Whether you're envisioning a new industrial facility, warehousing space, or other commercial ventures, this lot's expansive dimensions provide a solid foundation for realizing your investment goals. The generous space also allows for flexibility in design and layout, catering to a variety of industrial and commercial needs. This sizeable lot presents an exceptional opportunity for investors seeking to capitalize on the potential for growth and development in the Sikeston area.
Courtesy: Century 21 Ashland Realty
573-334-2121
Well established, family owned business in high visibility area for 30+ years. Downsizing and would split this property in a few different scenarios. The whole property would include two Morton buildings, one as an office and measuring approximately 24x48 with a 15x48 covered porch. The other building is a shop, measuring approximately 48x75 with 2 sets of drive-through doors and 2 walk through doors and 11 foot walls. But the owner would consider splitting this property sale a few different ways, with or without the front office building. Owner would also consider financing if buyer had considerable terms. Property all irrigated.
Courtesy: Smg Realty
573-472-4800
INVESTMENT OPPURTUNITY!! Feeders Supply (building), a Sikeston staple is now up for sale! Sale does not include business or inventory, just the building. Seller willing to sign a 3-5 year lease on the front 9,508 s/f. The remaining 7,350 s/f addition is separated into two spaces. 2,302 s/f of the addition in the very rear has been leased as a church and paid all of one year lease in advance. Great visibility from E. Malone Ave. Location: City, High Traffic
Courtesy: Lorimont L.c.
573-334-5200
Discover an exceptional investment opportunity with this 11,450 SF property featuring 7 units, built in 1988 in a coveted Sikeston area. With prime visibility from the main street, this versatile space offers a unique drive-thru infrastructure, catering to a range of business possibilities including restaurant, medical, office, or pharmacy use. Ideal for office space investors, the property's strategic location presents a compelling prospect for establishing a thriving commercial presence. Don't miss the chance to capitalize on this well-appointed property and take advantage of its exceptional features for your next office or office building investment. Floor plans are available upon request. Location: City, High Traffic
Courtesy: Century 21 Premiere Realty
573-472-2411
Prime Downtown Historic Properties - Timeless Elegance & Modern Potential Step into a piece of history with this exceptional 2 - story space located in the heart of downtown Sikeston. This is a great opportunity for a value-add investor, or someone wanting to relocate their existing business. The upstairs is a blank canvas with endless possibilities, and there are two leases on the ground floor, making it your chance to capitalize on the resurgence of downtown Sikeston. Positioned in a high-visibility, high-foot-traffic area, it's close to retail, professional services, and restaurants. This property offers a unique blend of historic charm and modern convenience. Originally built in 1915, this iconic building was the home of Buckner Ragsdale clothing store. High ceilings enhance the sense of openness. Don't miss the opportunity to own a piece of Sikeston's rich history. Envision the future of your business in this one-of-a-kind space. Location: Downtown
Courtesy: Silverthorn Realty, LLC
573-475-7044
Great commercial building in an excellent high traffic area!!! Building has a total of 7100 sq ft of space. Front parking lot, back parking lot, and both sides have parking. Currently is set up for 2 suites but can be broken down into multiple with 9 entry ways. One space is currently rented. The bigger space is set up right now with 5300 sq ft of space with 4 conference areas, 10 offices, 2 kitchens, and 3 bathrooms. Recent upgrades include 4 new air units, 3 new heaters, one bathroom completely remodeled, and roof work. Call for more details and a tour today! Location: City
Sikeston is located in Missouri. Sikeston, Missouri has a population of 16,054. Sikeston is less family-centric than the surrounding county with 24.96% of the households containing married families with children. The county average for households married with children is 27.44%.
The median household income in Sikeston, Missouri is $46,029. The median household income for the surrounding county is $50,556 compared to the national median of $69,021. The median age of people living in Sikeston is 37.8 years.
The average high temperature in July is 90.8 degrees, with an average low temperature in January of 26.7 degrees. The average rainfall is approximately 48.1 inches per year, with 3.7 inches of snow per year.
