The Clint Eastwood Building104 E 2nd Street Clarksdale, MSCorner of Delta Ave & 2nd Street Historic Blues DistrictOriginally built circa 1897 as a Clarksdale telegraph building, this iconic downtown property sits in one of the most walkable and recognizable locations in the Blues District--just steps from Hambone Art Gallery, the hostel, and the heart of Clarksdale's music scene.⸻Property Overview +/-10,430 Sq Ft Total Prime corner location (Delta Ave & 2nd Street) 3 fully operational short-term rental flats 2 income-producing commercial spaces Unrenovated upper level with major upside Rear parking access New roofThis is a rare opportunity to own a true mixed-use, income-producing property with immediate cash flow and significant value-add potential.⸻Income-Producing ComponentsShort-Term Rental Flats (Ground Level - 2nd Street)Positioned directly across from Hambone and the hostel, these units are walkable to all major blues venues and are designed with authentic Delta character.Each flat is fully furnished and decorated with Blues art and vintage decor, giving it a classic Delta blues style. Hooker Hotel Squeeze Box Delta DiggsAll three are turnkey, professionally designed, and actively used for short-term rentals.⸻Commercial Spaces (Delta Ave Frontage) Former Rug Gallery - Ideal for retail or lease income Clarksdale Alterations - Currently rented with established income⸻Upper Level (Unrenovated) Full floor with blank slate potential Ideal for condo development, event space, or expanded lodging Previously envisioned as a rooftop bar/lounge experience Opportunity to tie into existing rental units for increased revenue⸻Flat DetailsHooker Hotel (+/-745 Sq Ft 2BR / 1BA) Two large private bedrooms (king beds) Full kitchen + dining area Living space with wet bar + booth seating Custom 4x5 stone & slate walk-in shower Hardwood floors, reclaimed barn wood walls, tin ceilings Sliding barn door, track lighting Central heat & air, WiFi⸻Squeeze Box (+/-425 Sq Ft 1BR / 1BA) Ground level with covered veranda King bedroom Exposed brick + hardwood floors Wraparound sofa + booth seating Cypress bar with street-facing window seating Sliding metal doors Central heat & air, WiFi⸻Delta Diggs (+/-425 Sq Ft 1BR / 1BA) Queen bedroom Hardwood floors + dining booth Full kitchen (refrigerator, microwave) Custom 4x5 shower with Speakman fixtures Central heat & air, WiFi⸻Highlights & Recap Turnkey income from 3 STR units + 2 commercial spaces Prime downtown location in the Blues District Authentic Delta design throughout Significant upside with unfinished upper level New roof + rear parking⸻With built-in income, strong rental appeal, and a clear path for expansion, this building offers both immediate return and long-term upside. A true investment opportunity in the heart of the Delta.
A commercial retail building for sale located at 417 Desoto Ave in Clarksdale, Coahoma County. This spacious property features 5,000+/- square feet and was previously used as a furniture business, making it highly adaptable for a variety of ventures. Whether you are looking to start your own business or are an established enterprise seeking to expand, this is a fantastic opportunity. Don't miss out on the chance to invest in a property with great potential!
Commercial building for sale located at 855 S State Street in Clarksdale, Coahoma County. This property has been operated as a clothing store and features 6,000 square feet of retail space, along with an additional 4,000 square feet of storage in the back. Situated in a prime location on State Street, this is an excellent opportunity for anyone looking to open a retail store. Don't miss out on this spacious commercial building!
Iconic Delta Avenue Corner Property in the Heart of Clarksdale's Blues District271 Delta Avenue Business Opportunity at this standout downtown property on the iconic corner of Delta Avenue and 3rd Street--just one block from Ground Zero Blues Club and steps from the heart of Clarksdale's music scene. Four upstairs apartments set this property apart, offering built-in rental income that is ready for immediate bookings! Featuring a classic brick exterior, wrought-iron details, decorative balconies, and gated entrances, the building blends a touch of New Orleans character with the soulful architectural style of the Mississippi Delta.Upstairs, the four unique one-bedroom apartments come generously furnished, each with its own personality and charm. The premier corner suite features six oversized windows overlooking Delta Avenue, filling the space with natural light and the unmistakable sound of live blues drifting up from the street below. Original hardwood floors, exposed brick, antique lighting, and tall ceilings make this unit a true retreat above the music. The remaining apartments offer kitchens, living spaces, and full baths--ideal for long-term tenants, short-term guests, or an owner-occupied setup. These apartments are ready to book and provide immediate income producing potential!Downstairs, the property includes two commercial spaces. Facing Delta Avenue, ''The Gallery'' is partially renovated and full of potential, featuring leaded glass windows, exposed brick, original transom doorways, and a private courtyard with a charming wrought iron gate. Around the corner on 3rd Street, the second space is home to the world-famous Deak's Harmonica Shop--a staple in Clarksdale that draws musicians and tourists from all over.Whether you're looking for an income-producing investment, a downtown residence, or a truly one-of-a-kind mixed-use property, 271 Delta Avenue delivers. Step into the rhythm of Clarksdale and make this historic corner your own.Highlights and Recap:Location & ArchitectureIconic corner of Delta Ave & 3rd Street, one block from Ground Zero Blues ClubEarly 20th-century commercial architecture with subtle New Orleans-influenced detailsBrick exterior, wrought iron balconies and gates, arched French doors, transom windows, and interior exposed brickTPO Roof!Walkable to music venues, shops, restaurants, and major cultural attractionsResidential & Ready to Book- Upstairs (4 One-Bedroom Apartments)Tall ceilings, exposed brick, crown molding, large windows, and generously furnished! Apt 1 (Corner Suite): Hardwood floors, antique lighting, renovated kitchen with island, dining area, spacious living room, master suite, six tall windows facing Delta Ave, (2) mini-split HVAC systemsApt 2: Full kitchen, bedroom overlooking 3rd Street, full bath, central heat + window ACApt 3: Living room, Kitchenette setup, bedroom overlooking 3rd Street, full bath, central heat/air + window unitApt 4: Full kitchen, living/dining area, bedroom overlooking 3rd Street, full bath, central heat/air + window unitCommercial - Downstairs (2 Spaces)1. The Gallery (Delta Ave Frontage):Partially renovated with exposed brick and leaded glassOriginal transom doorsPrivate wrought iron gated entrance1/2 bathPrivate courtyard for outdoor use and atmosphere2. Deak's Harmonica Shop (3rd Street):Currently leased to a world-famous harmonica and music shopStrong tourism and cultural drawBusiness Opportunity/Investment Highlights: Premier location in Clarksdale's blues districtVersatile income: long-term rentals, short-term stays, boutique lodging, or live/work setups. Rental income, ready to go! Rare corner property with historic charm and consistent visitor appeal
Red Panther / Coahoma WarehousingNormandy Ave, Clarksdale, Mississippi 11 Acres 8 Buildings + Vacant LotNow available: a rare commercial/industrial opportunity at the site of the former Red Panther Chemical Company, located between Normandy and East Tallahatchie Avenues in Clarksdale, Mississippi. This property spans around 11 acres and offers a versatile mix of warehouse space, office facilities, storage buildings, a vacant lot, and ample parking, making it ideal for commercial operations involving heavy equipment, agriculture, grain storage, or warehousing.Property BackgroundFrom 1949 to 1996, the site operated as a pesticide formulation plant, producing liquid and dry herbicides, insecticides, and fungicides. Environmental cleanup activities were completed by the EPA and Mississippi Department of Environmental Quality, and the EPA officially closed its file, clearing the way for future development and sale.Site FeaturesMultiple Warehouse Buildings (constructed between 1962-1989)Office Building (6,420 SF)Drive-in doors and dock doors with rampsHigh-pressure fluorescent lighting throughoutGravel parking lotVacant lot for future development or outdoor storageCeiling heights up to 22 feet⸻Building DetailsBuilding #15 - WarehouseBuilt 1989 26,080 SF 14' wall / 20' ceiling1 Dock Door 1 Drive-in with RampBuilding #16 - WarehouseBuilt 1973 28,300 SF (100' x 283') 14' wall / 21' ceiling2 Dock Doors 1 Drive-in with RampBuilding #17 - WarehouseBuilt 1973 9,600 SF (60' x 160')1 Dock Door 1 Drive-in with RampBuilding #18 - WarehouseBuilt 1962 7,000 SF (100' x 170')1 Ground-Level Drive-in DoorBuilding #20 - Storage BuildingBuilt 1988 6,000 SF (60' x 100')Fluorescent LightingBuilding #21 - WarehouseBuilt 1965 16,000 SF (100' x 160') 12' wall / 16' ceiling2 Dock Doors 1 Drive-in with Ramp Fluorescent LightingBuilding #22 - OfficeBuilt 1956, Remodeled 1972 6,420 SFFluorescent LightingBuilding #23 - WarehouseBuilt 1989 38,400 SF (160' x 240') 16.5' wall / 22' ceiling4 Dock Doors 1 Ground-Level Drive-in DoorHigh-Pressure Sodium & Fluorescent Lighting⸻Potential UsesHeavy Equipment OperationsAgricultural or Farm Supply CenterGrain Storage & ProcessingCommercial WarehousingEquipment or Vehicle StorageRedevelopment Opportunity⸻This expansive and flexible site is priced to move.
Andrea D. Conner, License 22561, Xome Inc., License 21183, [email protected], 844-400-XOME (9663), 750 State Highway 121 Bypass, Suite 100, Lewisville, TX 75067

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Clarksdale is located in Mississippi. Clarksdale, Mississippi has a population of 15,124. Clarksdale is less family-centric than the surrounding county with 11.22% of the households containing married families with children. The county average for households married with children is 15.16%.
The median household income in Clarksdale, Mississippi is $30,711. The median household income for the surrounding county is $31,312 compared to the national median of $69,021. The median age of people living in Clarksdale is 35.2 years.
The average high temperature in July is 92.5 degrees, with an average low temperature in January of 30.2 degrees. The average rainfall is approximately 53.2 inches per year, with 1 inches of snow per year.