Prime commercial opportunity in a high-traffic location! This fully renovated, approximately 3,800-square-foot commercial property is prominently situated on a corner lot along North State Street, one of Clarksdale's well-traveled thoroughfares, and conveniently located across from Church's Chicken. The property offers an impressive open-concept interior, providing tremendous flexibility for a variety of business uses. The spacious layout, large storefront windows, multiple entry points, high ceilings, and extensive floor space make it ideal for retail, office space, a showroom, an event venue, professional services, a restaurant concept, or other commercial venture, subject to applicable zoning and approvals.
Excellent opportunity to own a commercial property in the heart of Clarksdale! This well-maintained building offers a versatile layout with spacious rooms, multiple office or retail options, and ample parking. Ideal for professional offices, medical, retail, or service-based businesses. Great visibility and convenient location!
138 Sunflower Avenue Spacious Downtown Commercial Building with Two Separate Units Located in the heart of downtown Clarksdale, this spacious 5,000+/- square foot commercial building offers a flexible opportunity for an owner-user, investor, or a combination of both. Just a short walk from Delta Avenue, Ground Zero Blues Club, Yazoo Pass, and other downtown businesses and attractions, the property is centrally located along Sunflower Avenue with large front windows overlooking the street and toward the Sunflower River. Dating to approximately 1910, this classic brick downtown building was originally constructed as a single commercial space but has since been divided into two separate units, each with its own entrance from Sunflower Avenue. The layout provides excellent flexibility--occupy the entire building, operate your business from one side while leasing the other, or adapt the space for a different commercial use. Currently configured primarily for office use, the building offers approximately 8-10 offices total, with 4-5 offices on each side. Each unit has two half baths, and the larger main-office side also includes a front reception area, full kitchen, and large rear storage area. Situated on approximately .11 acres, the property previously served as a Farm Bureau office and is currently home to H&M Cleaners. While well suited for continued office or professional use, the size, dual-unit configuration, and downtown location offer potential for retail, service, studio, mixed commercial use, or another vision for the space. Highlights include 5,000+/- sq ft, .11+/- acres, two separate commercial units, separate street entrances, 8-10 potential offices, 4 half baths total, full kitchen, reception area, large rear storage area, large storefront windows, circa-1910 brick construction, central downtown location, and potential for owner occupancy with rental income.
Invest in the heart of downtown Clarksdale with this historic circa-1900 commercial property offering immediate rental income and a prime Delta Avenue location. Currently home to the central office of the Juke Joint Festival, this approximately 2,151-square-foot space offers an opportunity to purchase an established downtown property with a tenant already in place. The property features a classic brick exterior, TPO roof, central heat and air, and a storefront opening directly onto Delta Avenue with large display windows. The interior offers flexible retail and office space with a restroom, while a covered rear entrance provides additional access and potential for a future configuration with commercial space in front and residential space in the rear, subject to applicable approvals. The property sits beside a public courtyard and lighted pedestrian walkway connecting Delta Avenue to Sunflower Avenue and is just steps from the Delta Blues Museum, Ground Zero Blues Club, restaurants, shops, music venues, and other downtown attractions. This commercial space is part of a mixed-use building consisting of ground-floor commercial units and residential units above. The property is subject to an HOA with monthly dues of $500, which currently include property taxes, building insurance, and maintenance of common areas, including the roof. This unit has its own 911 address and is being offered for sale separately. Whether purchased as an investment with an established tenant or for a future commercial or mixed-use vision, 243 Delta Avenue offers an affordable opportunity to own a piece of historic downtown Clarksdale in the center of the city's blues and tourism district. Current lease in place. Please inquire for additional details.
Invest in the heart of downtown Clarksdale with this historic circa-1900 commercial property offering immediate rental income and a prime Delta Avenue location! Located at 247 Delta Avenue, this approximately 2,151-square-foot space is currently home to Delta Med Glo, an established medical aesthetics and wellness practice and an attractive part of the downtown commercial scene. The interior is well suited for its current use while offering flexibility for a variety of future commercial possibilities, with a front reception and waiting area, office space, multiple private treatment or consultation rooms, and additional flexible retail or workspace. The historic brick building features a TPO roof, central heat and air, and an attractive storefront opening directly onto Delta Avenue with large display windows, plus a covered rear entrance for convenient secondary access. The property sits beside a public courtyard and lighted pedestrian walkway connecting Delta Avenue to Sunflower Avenue, placing it in a truly central location within downtown Clarksdale. This commercial space is part of a mixed-use building consisting of ground-floor commercial units and residential units above. The property is subject to an HOA with monthly dues of $500, which currently include property taxes, building insurance, and maintenance of common areas, including the roof. This unit has its own 911 address and is being offered for sale separately. A Right of First Refusal is in place. Whether purchased as an investment with an established tenant already in place or for future retail, professional office, or other commercial use, 247 Delta Avenue offers an affordable opportunity to own a historic income-producing property in the heart of downtown Clarksdale. Current lease in place. Please inquire for additional details.
Exceptional commercial opportunity in the heart of Clarksdale and newly renovated! This 34,903+/- square foot building sits on a 1.32+/- acre corner lot with C-2 zoning, allowing for retail, office, warehouse, or mixed-use development. The property features approximately 22,373 square feet of showroom space with expansive plate glass display windows and 12,531 square feet of warehouse space complete with two loading docks. Interior improvements include a large retail showroom, three private offices, customer service area, restroom facilities, and an open floor plan offering flexibility for a variety of commercial uses. Recent updates include a new central heating and air system (approximately one year old), TPO roof installed approximately seven years ago, new wall-to-wall carpet, new ceiling tiles throughout, new deluxe laminate flooring and baseboards in the offices, new insulation, freshly painted exterior, replaced rear warehouse gutters, and a fire sprinkler system. The property also offers approximately 15,259 square feet of paved parking with 10 dedicated parking spaces, outstanding visibility, and easy access from one of Clarksdale's busiest commercial corridors. Whether you're expanding an existing business, opening a retail showroom, creating office space, or investing in a highly versatile commercial property, this well-maintained building is ready for its next chapter.
Opportunity awaits in the heart of downtown Clarksdale! Located on historic Delta Avenue, one of the city's busiest and most recognizable streets, this 5,371-square-foot brick commercial building has outstanding visibility and is just steps from Ground Zero Blues Club and all of Clarksdale's most popular blues attractions. This well know commercial space is currently home to Nellie May's, a well-established downtown Clarksdale boutique. The building features large retail display windows along Delta Avenue, providing excellent street presence, while two side access doors offer convenient private entrances to the rear office space, which has excellent potential for an apartment, Airbnb, or additional office space. Currently tenant occupied, the property offers immediate rental income while providing outstanding long-term investment potential. In addition, the back 1/3 of the building is a large open warehouse space with the potential for 1 or 2 apartments. Whether you're looking to expand your portfolio, establish a downtown business, or create a mixed-use property, this building offers flexibility in one of Clarksdale's most desirable commercial locations. Surrounded by Clarksdale's iconic murals and downtown atmosphere, this property is positioned to benefit from the steady flow of both local and tourist traffic that makes Delta Avenue a destination year-round. Seller requests that prospective buyers be prequalified prior to scheduling a showing.
The Clint Eastwood Building 104 E 2nd Street Clarksdale, MS Corner of Delta Ave & 2nd Street Historic Blues District Originally built circa 1897 as a Clarksdale telegraph building, this iconic downtown property sits in one of the most walkable and recognizable locations in the Blues District--just steps from Hambone Art Gallery, the hostel, and the heart of Clarksdale's music scene. ⸻ Property Overview +/-10,430 Sq Ft Total Prime corner location (Delta Ave & 2nd Street) 3 fully operational short-term rental flats 2 income-producing commercial spaces Unrenovated upper level with major upside Rear parking access New roof This is a rare opportunity to own a true mixed-use, income-producing property with immediate cash flow and significant value-add potential. ⸻ Income-Producing Components Short-Term Rental Flats (Ground Level - 2nd Street) Positioned directly across from Hambone and the hostel, these units are walkable to all major blues venues and are designed with authentic Delta character. Each flat is fully furnished and decorated with Blues art and vintage decor, giving it a classic Delta blues style. Hooker Hotel Squeeze Box Delta Diggs All three are turnkey, professionally designed, and actively used for short-term rentals. ⸻ Commercial Spaces (Delta Ave Frontage) Former Rug Gallery - Ideal for retail or lease income Clarksdale Alterations - Currently rented with established income ⸻ Upper Level (Unrenovated) Full floor with blank slate potential Ideal for condo development, event space, or expanded lodging Previously envisioned as a rooftop bar/lounge experience Opportunity to tie into existing rental units for increased revenue ⸻ Flat Details Hooker Hotel (+/-745 Sq Ft 2BR / 1BA) Two large private bedrooms (king beds) Full kitchen + dining area Living space with wet bar + booth seating Custom 4x5 stone & slate walk-in shower Hardwood floors, reclaimed barn wood walls, tin ceilings Sliding barn door, track lighting Central heat & air, WiFi ⸻ Squeeze Box (+/-425 Sq Ft 1BR / 1BA) Ground level with covered veranda King bedroom Exposed brick + hardwood floors Wraparound sofa + booth seating Cypress bar with street-facing window seating Sliding metal doors Central heat & air, WiFi ⸻ Delta Diggs (+/-425 Sq Ft 1BR / 1BA) Queen bedroom Hardwood floors + dining booth Full kitchen (refrigerator, microwave) Custom 4x5 shower with Speakman fixtures Central heat & air, WiFi ⸻ Highlights & Recap Turnkey income from 3 STR units + 2 commercial spaces Prime downtown location in the Blues District Authentic Delta design throughout Significant upside with unfinished upper level New roof + rear parking ⸻ With built-in income, strong rental appeal, and a clear path for expansion, this building offers both immediate return and long-term upside. A true investment opportunity in the heart of the Delta. Seller requests that prospective buyers be prequalified prior to scheduling a showing.
A commercial retail building for sale located at 417 Desoto Ave in Clarksdale, Coahoma County. This spacious property features 5,000+/- square feet and was previously used as a furniture business, making it highly adaptable for a variety of ventures. Whether you are looking to start your own business or are an established enterprise seeking to expand, this is a fantastic opportunity. Don't miss out on the chance to invest in a property with great potential!
Commercial building for sale located at 855 S State Street in Clarksdale, Coahoma County. This property has been operated as a clothing store and features 6,000 square feet of retail space, along with an additional 4,000 square feet of storage in the back. Situated in a prime location on State Street, this is an excellent opportunity for anyone looking to open a retail store. Don't miss out on this spacious commercial building!
Iconic Delta Avenue Corner Property in the Heart of Clarksdale's Blues District 271 Delta Avenue Business Opportunity at this standout downtown property on the iconic corner of Delta Avenue and 3rd Street--just one block from Ground Zero Blues Club and steps from the heart of Clarksdale's music scene. Four upstairs apartments set this property apart, offering built-in rental income that is ready for immediate bookings! Featuring a classic brick exterior, wrought-iron details, decorative balconies, and gated entrances, the building blends a touch of New Orleans character with the soulful architectural style of the Mississippi Delta. Upstairs, the four unique one-bedroom apartments come generously furnished, each with its own personality and charm. The premier corner suite features six oversized windows overlooking Delta Avenue, filling the space with natural light and the unmistakable sound of live blues drifting up from the street below. Original hardwood floors, exposed brick, antique lighting, and tall ceilings make this unit a true retreat above the music. The remaining apartments offer kitchens, living spaces, and full baths--ideal for long-term tenants, short-term guests, or an owner-occupied setup. These apartments are ready to book and provide immediate income producing potential! Downstairs, the property includes two commercial spaces. Facing Delta Avenue, ''The Gallery'' is partially renovated and full of potential, featuring leaded glass windows, exposed brick, original transom doorways, and a private courtyard with a charming wrought iron gate. Around the corner on 3rd Street, the second space is home to the world-famous Deak's Harmonica Shop--a staple in Clarksdale that draws musicians and tourists from all over. Whether you're looking for an income-producing investment, a downtown residence, or a truly one-of-a-kind mixed-use property, 271 Delta Avenue delivers. Step into the rhythm of Clarksdale and make this historic corner your own. Highlights and Recap: Location & Architecture Iconic corner of Delta Ave & 3rd Street, one block from Ground Zero Blues Club Early 20th-century commercial architecture with subtle New Orleans-influenced details Brick exterior, wrought iron balconies and gates, arched French doors, transom windows, and interior exposed brick TPO Roof! Walkable to music venues, shops, restaurants, and major cultural attractions Residential & Ready to Book- Upstairs (4 One-Bedroom Apartments) Tall ceilings, exposed brick, crown molding, large windows, and generously furnished! Apt 1 (Corner Suite): Hardwood floors, antique lighting, renovated kitchen with island, dining area, spacious living room, master suite, six tall windows facing Delta Ave, (2) mini-split HVAC systems Apt 2: Full kitchen, bedroom overlooking 3rd Street, full bath, central heat + window AC Apt 3: Living room, Kitchenette setup, bedroom overlooking 3rd Street, full bath, central heat/air + window unit Apt 4: Full kitchen, living/dining area, bedroom overlooking 3rd Street, full bath, central heat/air + window unit Commercial - Downstairs (2 Spaces) 1. The Gallery (Delta Ave Frontage): Partially renovated with exposed brick and leaded glass Original transom doors Private wrought iron gated entrance 1/2 bath Private courtyard for outdoor use and atmosphere 2. Deak's Harmonica Shop (3rd Street): Currently leased to a world-famous harmonica and music shop Strong tourism and cultural draw Business Opportunity/Investment Highlights: Premier location in Clarksdale's blues district Versatile income: long-term rentals, short-term stays, boutique lodging, or live/work setups. Rental income, ready to go! Rare corner property with historic charm and consistent visitor appeal Seller requests that prospective buyers be prequalified prior to scheduling a showing.
Andrea D. Conner, License 22561, Xome Inc., License 21183, [email protected], 844-400-XOME (9663), 750 State Highway 121 Bypass, Suite 100, Lewisville, TX 75067

The data relating to real estate for sale on this web site comes in part from the IDX/RETS Program of MLS United, LLC. IDX/RETS real estate listings displayed which are held by other brokerage firms contain the name of the listing firm. The information being provided is for consumer's personal, non-commercial use and will not be used for any purpose other than to identify prospective properties consumers may be interested in purchasing. Information is deemed to be reliable but not guaranteed. Copyright 2021 MLS United, LLC. All rights reserved.
Clarksdale is located in Mississippi. Clarksdale, Mississippi has a population of 15,124. Clarksdale is less family-centric than the surrounding county with 11.22% of the households containing married families with children. The county average for households married with children is 15.16%.
The median household income in Clarksdale, Mississippi is $30,711. The median household income for the surrounding county is $31,312 compared to the national median of $69,021. The median age of people living in Clarksdale is 35.2 years.
The average high temperature in July is 92.5 degrees, with an average low temperature in January of 30.2 degrees. The average rainfall is approximately 53.2 inches per year, with 1 inches of snow per year.