Exceptional investment opportunity to acquire a premier boutique hotel in Sisters, Oregon. The Scout features six luxury guest cottages with upscale finishes, king suites, fireplaces, heated bathroom floors, spa-inspired baths, and curated interiors. A welcoming lobby and flexible gathering space supports retreats, weddings, reunions, corporate events, and exclusive buyouts. Walking distance to downtown Sisters with restaurants, breweries, galleries, boutique shopping, and year-round festivals. At the base of the Cascade Mountains, offering access to hiking, biking, skiing, fly fishing, golf, and lakes. Ideal for luxury hotel investors, commercial real estate buyers, and 1031 exchange investors seeking a turnkey, income-producing hospitality asset with strong demand and long-term appreciation in Central Oregon. Strong occupancy with room for growth, proven guest demand, and excellent cash flow opportunity.
Central Woof & Groom - Dog Boarding and Grooming Business - established since 2016 - is now for sale. This is the only Dog Boarding facility in the town of Sisters. This is your chance to own and operate your own business in the quaint and thriving town of Sisters, Oregon in Central Oregon. Check out the website: centralwoofandgroom
Don't miss your front row spot on the upcoming Adams Avenue improvements! This income producing cottage (previously a monthly rental) rests on a lot zoned DOWNTOWN COMMERCIAL. Keep as a single family home or investment, or max out the opportunities this property offers! Buyer to confirm with the city potential to divide. Downtown commercial permitted uses may include commercial space, live/work, cottage development, townhome, etc. Sisters is booming and properties like this don't come on the market often. This charming property is awaiting your vision!
Great investment opportunity. This two-story, 11,554 sq.ft. building features upper-level executive offices, a spacious kitchen, and outdoor seating. The main floor offers a generous entry, conference room, and a manufacturing/assembly area. In addition, an extensive distribution and storage center including radiant floor heating and dock-high delivery. Long-term business of 17 years in place. Current Triple Net lease runs 6 years with 2% annual increases, plus two additional 4-year options with market adjustments. Business is an International Company.
Well established and highly profitable Pizzeria located right in the heart of downtown Sisters with Hwy 126 frontage. Check the reviews and talk with locals, their reputation is unmatched. The business is turnkey and ready for a new owner group to step right in with the current owners offering training upon transfer. Operations are optimized with a specialty dough ball roller and dough press to allow faster and more consistent production. The ovens, dishwasher, soda machines, coolers, and all equipment included are in excellent condition. Seating inside and out allows for a great in-person dining experience, and they do very well with takeout orders throughout the year. The business has a customer bathroom up front and an employee bathroom at the back. Owners use Cake for point of sale and the operation completely organized and ready for a smooth transition! Financials are available for review with a signed NDA.
Once-in-a-lifetime opportunity! On the shores of a 28-acre alpine lake, the Three Creek Lake Store and Marina is now available! At 6,550 ft in the Deschutes National Forest, this beloved alpine business has served generations of outdoor enthusiasts and has steady visitors for fishing, boating, hiking, and camping. The cabin-style building houses a stocked general store with camping supplies, snacks, drinks, apparel, and local art, plus a full marina with canoes, paddle boards, fishing gear, and tackle. The property--the only cabin or structure on the lake--sits on just under an acre, offering a private camping spot, and is on a Forest Service lease, transferable with approval. Currently operated seasonally from Memorial Day to Labor Day, weather permitting. It can possibly be operated year-round with Forest Service approval. Turn-key, low-overhead, and irreplaceable--this is a rare chance to own a piece of Oregon history.
Sitting on .64 of an acre is this 10,500 sq ft industrial building in Sisters Industrial Park. This building features several offices as well as an open warehouse areas with three, 14ft roll up doors. The large warehouse area has 3 phase power.
Centrally located and walking distance to the quaint town of downtown Sisters, Oregon - this large 4,000 sq.ft. Commercial Building is available for purchase! The property is just less than a 1/3 of an acre with a large areas for parking and/or expansion. The building is currently fully NNN leased.
![]() |
| The content relating to real estate for sale on this website comes in part from the MLS of Central Oregon. Real estate listings held by Brokerages other than Xome Inc. are marked with the Reciprocity/IDX logo, and detailed information about these properties includes the name of the listing Brokerage. © MLS of Central Oregon (MLSCO). |

Sisters is located in Oregon. Sisters, Oregon has a population of 2,945. Sisters is more family-centric than the surrounding county with 33.23% of the households containing married families with children. The county average for households married with children is 29.18%.
The median household income in Sisters, Oregon is $81,016. The median household income for the surrounding county is $74,082 compared to the national median of $69,021. The median age of people living in Sisters is 48.5 years.
The average high temperature in July is 84.2 degrees, with an average low temperature in January of 23.2 degrees. The average rainfall is approximately 11.4 inches per year, with 16.1 inches of snow per year.