Exceptional Commercial Opportunity with Unlimited Potential! Unlock the possibilities with this highly versatile property, ideally positioned for commercial development, investment, redevelopment, or a variety of business ventures. Located adjacent to McLeod Health in one of the area's fastest-growing corridors, this prime site offers outstanding visibility, easy accessibility, and strong traffic exposure—key ingredients for long-term success. Whether you're an investor seeking your next strategic acquisition, a developer envisioning a transformative project, or an entrepreneur searching for the perfect location to establish or expand a business, this property presents a rare opportunity to bring your vision to life in a thriving market. Benefit from the momentum of continued growth and development surrounding this sought-after location while capitalizing on its exceptional potential and flexibility for future use. Property is being sold strictly as-is. Seller will make no repairs.
Great opportunity to own an established RESTAURANT WITH BAR BUSINESS AT THE CENTER OF FLORENCE, SC. 54 parking spaces, 110 seating capacity with beautiful Patio dining. Building and land not included in the sale.Transferable Lease available . Restaurant is open 6 days except on Tuesdays. Please do not disturb the workers or Clients. Disclaimer: CMLS has not reviewed and, therefore, does not endorse vendors who may appear in listings.
Prime B-6 Zoned Opportunity – Exceptional Commercial Potential! Take advantage of this versatile B-6 zoned property offering endless possibilities for commercial use, investment, or redevelopment. Conveniently situated between McLeod Health and MUSC Health Florence Medical Center, this prime location provides excellent accessibility and visibility in a rapidly growing area. An outstanding opportunity for investors, developers, or entrepreneurs looking to bring their vision to life. Property is being sold AS IS. Seller will make no repairs. Property was acquired through a tax sale and will not convey via General Warranty Deed or Special Warranty Deed. Seller will not be responsible for a Quiet Title Action.
Fully occupied retail center across the street from Walmart Neighborhood Market. 2 connected buildings- 817 S. Cashua (7,450 SF) and 823 S. Cashua (8,000 SF). Both buildings in good condition with high traffic count. Disclaimer: CMLS has not reviewed and, therefore, does not endorse vendors who may appear in listings.
Courtesy: CB Sea Coast Advantage MI
843-650-0998
For Sale Business Only: Established heavy truck and mobile repair franchise operation serving commercial fleets and roadside service customers throughout the Florence, South Carolina market. This business has seen strong revenue growth over the past 12 months, with increases in total revenue and average invoice value, and it has significant upside for continued expansion. The sale includes all equipment, inventory, operational systems, trade secrets, customer relationships, and training necessary to provide a true turnkey operation from day one. Currently, the business has contracts in place with 16 national and regional commercial fleet accounts and has built a strong reputation in the market for mobile service capability and fleet support. This is a confidential offering. All interested parties will be required to execute a Non-Disclosure Agreement before the release of any financials or additional business information. Lease assumption or a new lease will be available as options for a buyer. Owner financing options will also be available.
Positioned along high-traffic W Palmetto St , this well-located commercial property offers excellent visibility and accessibility in one of Florence’s most active corridors. Situated on a generous lot, the property provides ample space for parking, expansion, or a variety of business uses. Ideal for a tax office, professional services, or small business operations, the layout and location make it a versatile opportunity for owner-users or investors alike. Surrounded by established businesses and steady daily traffic, this property benefits from strong exposure and convenient access to major roadways. A great opportunity to establish or grow your business in a prime commercial area of Florence.
Prime 1.5 Acre Commercial Opportunity – Pine Needles Rd, Florence, SC Excellent opportunity to own 1.5 acres of commercial land in one of Florence’s fastest-growing corridors! Located on Pine Needles Rd, this property offers strong visibility and convenient access to surrounding residential and commercial developments. Almost 200 feet of road frontage on Pine Needles, for easy access! Positioned in a high-traffic area, the site is surrounded by established businesses and community staples including KJ’s IGA, Jiffy Lube, Hope Health, King’s Academy, Ebenezer Baptist Church, Ebenezer Park, and the West Florence Fire Department. The property is also just less than half a mile from a newly developed Publix, bringing increased traffic and continued growth to the area. With close proximity to The Grove subdivision, Ebenezer Chase subdivision, Westbrook subdivision, and Traces Golf Course, and other residential neighborhoods, this location is ideal for a variety of commercial uses such as retail, office space, or service-based businesses (buyer to verify zoning). Property Highlights: 1.5 Acres Prime location on Pine Needles Rd High growth area with strong surrounding development Less than 0.5 miles to Publix Near established businesses, schools, and residential communities Excellent potential for retail, office, or mixed-use development Don’t miss this chance to secure a well-positioned commercial site in a rapidly expanding area of Florence!
What a great looking property in a fantastic location! This commercial property offers excellent potential for a variety of uses including office, retail or service-based business, such as car lot, tax office, salon, etc. The layout features a front reception area with an oversized counter—plenty of workspace for client check-in, transactions or day-to-day operations—along with 3 private offices, a dedicated work area or conference room, break room and 1 bathroom. Conveniently located just 0.5 mile from the Florence Mall with high traffic volume, easy access and 20+ parking spaces. This one checks all the boxes—location, layout and visibility!
Welcome to 910 W Evans st, a beautifully remodeled commercial building just minutes from downtown Florence. This property has been completely gutted and rebuilt from the ground up — featuring a new roof, HVAC, electrical, and plumbing. Inside, you’ll find 5 spacious rooms that can serve as private offices or treatment spaces, plus a modern kitchen with brand-new cabinets and granite countertops. The layout includes 1 full bathroom and an additional half bath, offering flexibility for both clients and staff. Perfect for a medical office, salon, law firm, or small business looking for a turnkey property in a prime location with excellent visibility and access. Take a tour and see all the possibilities it has to offer!
Historic Building for Sale in the Heart of Downtown Florence This impressive 16,000 square foot historic building offers a rare opportunity in the thriving Downtown Florence area. With its expansive size and prime location, the potential for this property is limitless. Currently home to a Law Firm (13,759 sq ft), H&R Block (1,977 sq ft) , and Smith Hair Studio (568 sq ft), this versatile space is ideal for a variety of uses. The Law Firm occupies 23 offices, 7 bathrooms, 8 boardrooms and meeting spaces, a kitchen area, a library, and a designated reception and waiting area. Set on 1.47 acres, this remarkable building provides ample room for growth and development in one of Florence's most vibrant downtown districts. This property also offers over 100 parking spaces which is rare for a downtown area. Great opportunity for a truly unique property with endless potential.
This spacious, 2,900-square-foot property is both historic and handicap accessible, zoned for commercial or residential purposes. It features six entrances off a large wraparound porch and ten parking spaces. Inside, you'll find a sizeable reception area, six large additional rooms, three newly renovated full bathrooms, plus a generous kitchen and break room. Fully ADA compliant, the building includes two wheelchair ramps, widened interior doors, and both sprinkler and security systems. The 3 HVAC units were replaced in 2022, and the property boasts a newer roof. Schedule your showing today and feel free to submit any reasonable offer or terms.
This property is being sold "as is". The location of this property is prime and makes it worth the investment. Great location for business. There is a Sentri lockbox on the back door where the little patio is. The property is vacant so feel free to show anytime
Great location front on S Cashua next door to Walmart market after strip mall. being sold as is. Need 48 hours in advance for daycare showing appointment. Must show after 5:30 pm not during business hours. Lock box on backdoor Being sold as is! NO REPAIRS
Prime Commercial Opportunity on Freedom Blvd – 4.65 Acres Corner Lot Located at the high-visibility intersection of Freedom Blvd and Gilbert Drive, this approximately 4.65-acre tract offers exceptional potential for commercial development. Maintained by SCDOT and situated within Florence city limits, the property offers public water and sewer access and zoned Commercial General. Key Highlights: 706 ft of frontage on Freedom Blvd Extremely high traffic volume in both directions 2023 Traffic Counts: N. Williamson Rd to Freedom Blvd: 17,400 Freedom Blvd to Pamplico Hwy: 5,900 Pamplico Hwy to E National Cemetery Rd: 17,000 Adjacent to Freedom Estates residential community Across from Blue Granite Estate mobile home neighborhood Minutes from MUSC Florence Hospital and Medical Mall Ideal Uses (Subject to Planning Approval): Car wash, Gas station / convenience store, Food market, Auto repair shop, Mini storage facility. This rapidly expanding area offers a unique blend of residential and commercial growth, making it a strategic location for a wide range of business ventures. Buyer responsible for new survey. Seller willing to subdivide. TMP # 00179--01-014 was combined with TMP # 00178-01-244 for 4.65 acres.
TURN KEY READY and long established profitable fish market formally known as "Gulf Stream Seafood Marker" is loved by locals. This commercial building with approximately 2500 square feet of space is situated on 0.65 acres of land zoned for general commercial use on West Darlington Street in Florence, SC averages just over 10,900 daily traffic count. Just minutes away from thriving down town development. It is currently equipped with a spacious kitchen fully operable with a 6 burner commercial grade gas stove with overhead exhaust, 3 commercial grade gas deep fryer cookers, 1 8x12 Walk-In Cooler, 1 Arctic Air Commercial Refrigerator, 5 Stainless Steel Prep Tables, 5 Commercial Sinks, 3 hand washing sinks, 1 mop sink, New electrical wiring and plumbing in 2016, 1 Commercial grade Ice Machine, 1 Fresh Seafood Display Cooler, and 1 Beverage Cooler. Easily ready for the new owners to adopt and expand the existing concepts. Recently remodeled and redecorated dining room area has NEW ceiling tiles, NEW Light fixtures, and NEW ceiling fans that can seat 50+ dine in customers. High visibility and exposure just 5 minutes from the downtown district, 10 Minutes from Magnolia Mall, 10 minutes from I-95 and I-20 Interstate. SOLD with all dining furnishings, commercial grade appliances, and light fixtures.
Outstanding office building available for lease located at 620 W Evans Street near Downtown Florence, South Carolina. 620 W Evans is a standalone building with private parking, consisting of four private offices, numerous administrative work spaces, open concept work flow space, large conference room, storage and two restrooms. The building is +/- 3,000 sqft and there are 15+ parking spaces. The location has an AADT of 10,500 per SCDOT and offers great convenience to Downtown Florence, general business areas, I-95 and I-20. The property has been recently refreshed by new ownership and is under new management. There are lease options available; the advertised rate is for the entire space, 3 year lease as-is. There are also potential options of dividing the space for two users. Come grow your business at 620 W Evans Street!
This is a wonderful opportunity to own a historic property located in the heart of downtown Florence. The Griffin Motor Company building is listed on the National Register of Historic Places and is situated on the corner of Irby and Darlington Streets. The one-story building occupies an area of approximately 1.55 acres and has an estimated size of 12,411 square feet. All measurements are approximate and must be verified by the buyer, and are not related to the sales price.
Prime 7.96-acre commercial lot in Florence County, ideally situated just 1 mile from both McLeod Hospital and Florence Airport. This strategic location offers exceptional accessibility, making it a great opportunity for diverse commercial ventures just 5minutes from the growing Downtown Florence. Don't miss the chance to invest in this thriving area with proximity to key amenities and infrastructure.
Great investment opportunity. Three separate rentals. All buildings are currently rented out. Don't miss out on this 4740 square foot mixed use property. Conveniently located, offering great exposure to passing traffic! Property occupied. Please give 24 hours notice for showing
COMMERCIAL possibility. Currently occupied as a home by owner. It is residential at the moment, but it has been commercial before according to seller. Located next door to a medical staffing business. Great Location. Sq. ft does not include the building in the rear of the property.
Great opportunity to buy a commercial property in the downtown area. APPOINTMENTS ONLY!
Commercial Lot - with 100' frontage on Barringer Street. 2nd property down from the intersection of National Cemetery. High traffic location Several other properties totaling just under 4 acres located between Church St and Barringer Street for sale. Some with Commercial buildings, some lots currently zoned as commercial, some lots currently zoned as residential that back up to commercial properties.
Heavy traffic Location Close to downtown Florence, McLeod Hospital (less than 1 mile) as well as MUSC Hospital and Florence Regional Airport (both less than a 3 mile drive) Large lot (.82 acres), almost 250 feet frontage on Barringer Street. Property has large metal warehouse with concrete floor and loading dock. Other buildings also on the property. Multiple properties with frontage on Church Street are adjacent to this property and are for sale. Residential Home - fixer upper - adjacent to this property and fronts on Church Street also available for sale.
Currently Leased and Operating as a Mechanics/Auto Body Shop Two Metal Shops on property. One building has 4 bays the other has 2 Bays. High Traffic location. "Activity" zoning class with the city which includes a variety of uses. Lot that backs up to this property fronting on Church Street also available for sale. Owner has several properties for sale between Church Street and Barringer Street in close proximity. Close to downtown Florence, McLeod Hospital (less than 1 mile) as well as MUSC Hospital and Florence Regional Airport (both less than a 3 mile drive).
Property on the corner of Barringer and Cohen Street with Block Building with Concrete Floor. Two adjacent properties also for sale. Adjoining Vacant Lot on the Corner of Church and Cohen Streets. Adjoining property on Barringer Street has a Metal Building. Several other properties available for sale in close proximity between Church St. and Barringer Street. "Activity" zoning class with the city which includes a variety of uses. Heavy traffic daily Close to downtown Florence, McLeod Hospital (less than 1 mile) as well as MUSC Hospital and Florence Regional Airport (both less than a 3 mile drive)
Andrea D. Conner, License 102111, Xome Inc., License 19633, [email protected], 844-400-XOME (9663), 751 Highway 121 Bypass, Suite 100, Lewisville, Texas 75067
The information being provided is for the consumer's personal, non-commercial use and may not be used for any purpose other than to identify prospective properties consumer may be interested in purchasing. Any information relating to real estate for sale referenced on this web site comes from the Internet Data Exchange (IDX) program of the Consolidated MLS®. This web site may reference real estate listing(s) held by a brokerage firm other than the broker and/or agent who owns this web site. The accuracy of all information, regardless of source, including but not limited to square footages and lot sizes, is deemed reliable but not guaranteed and should be personally verified through personal inspection by and/or with the appropriate professionals. Copyright © 2026, Consolidated MLS®.
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| Provided courtesy of the Coastal Carolinas MLS. Copyright 2026 of the Coastal Carolinas MLS. All rights reserved. Information is provided exclusively for consumers' personal, non-commercial use, and may not be used for any purpose other than to identify prospective properties consumers may be interested in purchasing, and that the data is deemed reliable but is not guaranteed accurate by the Coastal Carolinas MLS. |
Florence is located in South Carolina. Florence, South Carolina has a population of 39,816. Florence is more family-centric than the surrounding county with 27.93% of the households containing married families with children. The county average for households married with children is 26.6%.
The median household income in Florence, South Carolina is $52,425. The median household income for the surrounding county is $51,902 compared to the national median of $69,021. The median age of people living in Florence is 39.2 years.
The average high temperature in July is 91.7 degrees, with an average low temperature in January of 33.2 degrees. The average rainfall is approximately 45.2 inches per year, with 0.8 inches of snow per year.
