Excellent opportunity to acquire a 4,500 SF industrial service facility situated on 2.55 acres along Mechanicsville Road in Florence, South Carolina. Conveniently located near I-95 Exit 164 (US Highway 52), providing excellent access to the interstate corridor for truck repair, fleet maintenance, and industrial service operations. Currently utilized as a diesel truck repair shop, the property features 16-foot ceiling height, two drive-through service bays, and four 14-foot roll-up doors, providing convenient access for large trucks and commercial vehicles. The facility includes one vehicle lift and an extensive assortment of shop equipment, tools, and replacement parts inventory that convey with the sale. Equipment includes air compressors, tire balancer, parts washer, 500-gallon oil tank with pump, Clean Burn heating system, and various maintenance and repair tools. The 2.55-acre site offers substantial potential for outdoor truck parking, equipment storage, and fleet operations. The property is currently minimally graveled and unfenced, allowing a purchaser to improve and configure the yard to accommodate specific operational needs. Ideally suited for diesel truck repair, fleet maintenance, heavy equipment service, trucking operations, or contractor-related businesses, this property offers an excellent opportunity for an owner-user seeking a functional industrial service facility with equipment already in place. Property Highlights • 4,500 SF industrial service building • 2.55-acre site • 16-foot ceiling height • Two drive-through service bays • Four 14-foot roll-up doors • One vehicle lift • Existing diesel truck repair use • Extensive shop equipment and parts inventory included • Air compressors, tire balancer, parts washer, and shop heating system • Outdoor area with potential for truck parking, fleet storage, and equipment staging • Opportunity for yard improvements and customization • Multiple potential industrial and service uses
Courtesy: Realty ONE Group DocksideNorth
843-663-4030
INCREDIBLE OPPORTUNITY! This is not raw, unzoned land - it is a fully permitted, turnkey industrial aggregate, C&D recycling, and organic processing facility sitting on over 54 ACRES. *Triple Permitted Operating Permits* Active 44 acre mining permit (sand, clay and topsoil extraction), Active C&D recycling permit (concrete and asphalt crushing/processing) Active wood chipping permit (land clearing and organic processing). Obtaining modern mine permitting in Florence County is a difficult task considering all of the strict setbacks and buffer zones. Having these permits actively in place bypasses years of Board of Zoning appeals (BZA) battles and state environmental reviews. Immediate on-site stockpile value (ask your agents for details), ~20,000 tons of recyclable concrete stack (ready to be crushed), ~100,000 Cu Yds of sand, clay, and topsoil in-ground/processed, ~24,000 Cu Yds of processed mulch/wood inventory. Perfect for Heavy civil contractors, paving/asphalt operators, aggregate suppliers, site-prep firms and C&D recycling companies near the AESC Giga Factory, Amazon fulfillment hubs and major DOT highway expansions. This turnkey property offers buyers immediate operational authority, substantial on-site material inventory, and an unbeatable industrial location along Florence's primary growth corridor. ~5 minutes to I-95/I-20 Interchange. Call today!
Location, Location, Location! Conveniently situated between Second Loop Road and West Palmetto Street, this brick property offers an excellent opportunity for a professional office or business location in Florence! Currently operating as an insurance office, the thoughtfully designed layout features four dedicated private offices, a spacious conference room, welcoming lobby and reception area, two bathrooms, and a kitchenette. Outside, you’ll find a patio area and a detached 20x24 insulated storage building, providing additional space for storage or business needs. Recent improvements include a new roof in 2025, and interior doors replaced in 2025. Additional features include a gravel driveway, a transferable HVAC maintenance contract with Swift Heating & Cooling, and termite and pest control service through Harris Pest Control. With its convenient location, functional layout, and valuable updates, this property offers flexibility for a variety of professional uses. Whether you’re looking to establish your business or relocate to a convenient Florence location, 2217 W Driftwood Avenue is worth a look!
Excellent opportunity to own a church property situated on approximately 2 acres of prime real estate at 111 N. Williams Street. Offering approximately 3,000 square feet, the building features a spacious 1,350-square-foot sanctuary, multiple classrooms, and two bathrooms. The functional layout provides ample space for worship services, religious education, meetings, and other activities. The generous 2-acre parcel offers additional outdoor space and potential for future expansion or redevelopment, subject to applicable zoning and approvals. Whether continuing its use as a place of worship or exploring other possibilities, this property presents an excellent investment opportunity. Schedule your showing today! Acreage is an estimate.
Adjacent to the new, 45,000 square feet Francis Marion University Medical Consortium on Gregg Ave. Approximately 3200 square feet, this professional office building features 10 offices, receptionist area, lobby area, break room, 4 bathrooms, 2 separate exits for both the top and bottom floor and a dedicated parking lot. Upgrades include new plumbing and electrical throughout, recessed lighting throughout, new HVAC units and air handlers, new roof, CCTV cameras for security, carpeted offices and LVP common areas, new crawlspace access and moisture barrier in crawl space. City water and sewer, Duke Energy for electricity, Spectrum for internet. Disclaimer: CMLS has not reviewed and, therefore, does not endorse vendors who may appear in listings.
Commercial Investment Opportunity – Florence, SC -Great opportunity to own a 4,720 sq. ft. mixed-use commercial property in Florence! This income-producing property features three separate rental units, all currently occupied, providing immediate rental income for the new owner. -Conveniently located in a high-traffic area with excellent visibility, this property offers a strong opportunity for an investor looking to add an established, fully occupied commercial property to their portfolio. -Highlights: 4,720 sq. ft. • 3 separate rental units • 100% currently occupied • Mixed-use property • High-traffic location • Immediate income-producing investment opportunity Excellent opportunity for investors—schedule your showing today!
Prime exposure on West Palmetto Street, one of Florence’s main thoroughfares. Currently used as a law office, this versatile property offers excellent potential for continued professional use or conversion into a single-family residence. The main level features three spacious rooms ideal for private offices or bedrooms, along with a large den that can easily serve as a reception and client waiting area. A downstairs kitchen and dining area provide additional flexibility. Upstairs, a private efficiency apartment includes a bedroom, bathroom, kitchen, and small living area—perfect for rental income, guest accommodations, or convenient on-site living. With outstanding visibility, flexible space, and multiple potential uses, this is a unique opportunity in a highly accessible Florence location. Buyer and buyer’s agent should verify zoning and permitted uses.
Church building that includes baptism pool, offices and restrooms. Ready for you to make your own Disclaimer: CMLS has not reviewed and, therefore, does not endorse vendors who may appear in listings.
Looking for a Business Opportunity? Eastside Frame and Body Auto Collision and Repair has been successfully operating over 30 years. Conveniently located approx. 5 minutes from downtown Florence this turnkey operation is ideal for an Investor or Owner-operator ready to step into a profitable, established, and well-respected business. Fully fenced in and located on a corner lot, Eastside Frame and Body offers 2 offices, 6 Bays, both customer and staff restrooms, reception area, and features a Downdraft paint room and Lift. Sale includes parts inventory, lift, tools, paints, all office furniture and equipment, security cameras and alarms. Also includes Business name, Phone number, Signage and Client Roster.
Listed at $1,650,000, 1706 2nd Loop Road offers an 8,300 sq ft commercial facility on 1.34 acres with CI zoning and outstanding visibility. Formerly a cardiology practice, the building includes 13 exam rooms, X-ray room, reception lobby, multiple executive and administrative offices, board room, and extensive storage—including a fully floored attic. Exterior features include a covered patient drop-off, four-bay carport, and 62 parking spaces. A turnkey opportunity ideal for medical, professional, or institutional use.
Exceptional Commercial Opportunity with Unlimited Potential! Unlock the possibilities with this highly versatile property, ideally positioned for commercial development, investment, redevelopment, or a variety of business ventures. Located adjacent to McLeod Health in one of the area's fastest-growing corridors, this prime site offers outstanding visibility, easy accessibility, and strong traffic exposure—key ingredients for long-term success. Whether you're an investor seeking your next strategic acquisition, a developer envisioning a transformative project, or an entrepreneur searching for the perfect location to establish or expand a business, this property presents a rare opportunity to bring your vision to life in a thriving market. Benefit from the momentum of continued growth and development surrounding this sought-after location while capitalizing on its exceptional potential and flexibility for future use. Property is being sold strictly as-is. Seller will make no repairs.
Great opportunity to own an established RESTAURANT WITH BAR BUSINESS AT THE CENTER OF FLORENCE, SC. 54 parking spaces, 110 seating capacity with beautiful Patio dining. Building and land not included in the sale.Transferable Lease available . Restaurant is open 6 days except on Tuesdays. Please do not disturb the workers or Clients. Disclaimer: CMLS has not reviewed and, therefore, does not endorse vendors who may appear in listings.
Prime B-6 Zoned Opportunity – Exceptional Commercial Potential! Take advantage of this versatile B-6 zoned property offering endless possibilities for commercial use, investment, or redevelopment. Conveniently situated between McLeod Health and MUSC Health Florence Medical Center, this prime location provides excellent accessibility and visibility in a rapidly growing area. An outstanding opportunity for investors, developers, or entrepreneurs looking to bring their vision to life. Property is being sold AS IS. Seller will make no repairs. Property was acquired through a tax sale and will not convey via General Warranty Deed or Special Warranty Deed. Seller will not be responsible for a Quiet Title Action.
Fully occupied retail center across the street from Walmart Neighborhood Market. 2 connected buildings- 817 S. Cashua (7,450 SF) and 823 S. Cashua (8,000 SF). Both buildings in good condition with high traffic count. Disclaimer: CMLS has not reviewed and, therefore, does not endorse vendors who may appear in listings.
Courtesy: CB Sea Coast Advantage MI
843-650-0998
For Sale Business Only: Established heavy truck and mobile repair franchise operation serving commercial fleets and roadside service customers throughout the Florence, South Carolina market. This business has seen strong revenue growth over the past 12 months, with increases in total revenue and average invoice value, and it has significant upside for continued expansion. The sale includes all equipment, inventory, operational systems, trade secrets, customer relationships, and training necessary to provide a true turnkey operation from day one. Currently, the business has contracts in place with 16 national and regional commercial fleet accounts and has built a strong reputation in the market for mobile service capability and fleet support. This is a confidential offering. All interested parties will be required to execute a Non-Disclosure Agreement before the release of any financials or additional business information. Lease assumption or a new lease will be available as options for a buyer. Owner financing options will also be available.
Prime 1.5 Acre Commercial Opportunity – Pine Needles Rd, Florence, SC Excellent opportunity to own 1.5 acres of commercial land in one of Florence’s fastest-growing corridors! Located on Pine Needles Rd, this property offers strong visibility and convenient access to surrounding residential and commercial developments. Almost 200 feet of road frontage on Pine Needles, for easy access! Positioned in a high-traffic area, the site is surrounded by established businesses and community staples including KJ’s IGA, Jiffy Lube, Hope Health, King’s Academy, Ebenezer Baptist Church, Ebenezer Park, and the West Florence Fire Department. The property is also just less than half a mile from a newly developed Publix, bringing increased traffic and continued growth to the area. With close proximity to The Grove subdivision, Ebenezer Chase subdivision, Westbrook subdivision, and Traces Golf Course, and other residential neighborhoods, this location is ideal for a variety of commercial uses such as retail, office space, or service-based businesses (buyer to verify zoning). Property Highlights: 1.5 Acres Prime location on Pine Needles Rd High growth area with strong surrounding development Less than 0.5 miles to Publix Near established businesses, schools, and residential communities Excellent potential for retail, office, or mixed-use development Don’t miss this chance to secure a well-positioned commercial site in a rapidly expanding area of Florence!
Historic Building for Sale in the Heart of Downtown Florence This impressive 16,000 square foot historic building offers a rare opportunity in the thriving Downtown Florence area. With its expansive size and prime location, the potential for this property is limitless. Currently home to a Law Firm (13,759 sq ft), H&R Block (1,977 sq ft) , and Smith Hair Studio (568 sq ft), this versatile space is ideal for a variety of uses. The Law Firm occupies 23 offices, 7 bathrooms, 8 boardrooms and meeting spaces, a kitchen area, a library, and a designated reception and waiting area. Set on 1.47 acres, this remarkable building provides ample room for growth and development in one of Florence's most vibrant downtown districts. This property also offers over 100 parking spaces which is rare for a downtown area. Great opportunity for a truly unique property with endless potential.
Prime Commercial Opportunity on Freedom Blvd – 4.65 Acres Corner Lot Located at the high-visibility intersection of Freedom Blvd and Gilbert Drive, this approximately 4.65-acre tract offers exceptional potential for commercial development. Maintained by SCDOT and situated within Florence city limits, the property offers public water and sewer access and zoned Commercial General. According to the CITY OF FLORENCE zoning specialist, multi family & townhomes are permitted under the present general commercial zoning. However, duplexes & SFR will require re zoning. Key Highlights: 706 ft of frontage on Freedom Blvd Extremely high traffic volume in both directions 2023 Traffic Counts: N. Williamson Rd to Freedom Blvd: 17,400 Freedom Blvd to Pamplico Hwy: 5,900 Pamplico Hwy to E National Cemetery Rd: 17,000 Adjacent to Freedom Estates residential community Across from Blue Granite Estate mobile home neighborhood Minutes from MUSC Florence Hospital and Medical Mall Ideal Uses (Subject to Planning Approval): Car wash, Gas station / convenience store, Food market, Auto repair shop, Mini storage facility. This rapidly expanding area offers a unique blend of residential and commercial growth, making it a strategic location for a wide range of business ventures. Buyer responsible for new survey. Seller willing to subdivide. TMP # 00179--01-014 was combined with TMP # 00178-01-244 for 4.65 acres.
TURN KEY READY and long established profitable fish market formally known as "Gulf Stream Seafood Marker" is loved by locals. This commercial building with approximately 2500 square feet of space is situated on 0.65 acres of land zoned for general commercial use on West Darlington Street in Florence, SC averages just over 10,900 daily traffic count. Just minutes away from thriving down town development. It is currently equipped with a spacious kitchen fully operable with a 6 burner commercial grade gas stove with overhead exhaust, 3 commercial grade gas deep fryer cookers, 1 8x12 Walk-In Cooler, 1 Arctic Air Commercial Refrigerator, 5 Stainless Steel Prep Tables, 5 Commercial Sinks, 3 hand washing sinks, 1 mop sink, New electrical wiring and plumbing in 2016, 1 Commercial grade Ice Machine, 1 Fresh Seafood Display Cooler, and 1 Beverage Cooler. Easily ready for the new owners to adopt and expand the existing concepts. Recently remodeled and redecorated dining room area has NEW ceiling tiles, NEW Light fixtures, and NEW ceiling fans that can seat 50+ dine in customers. High visibility and exposure just 5 minutes from the downtown district, 10 Minutes from Magnolia Mall, 10 minutes from I-95 and I-20 Interstate. SOLD with all dining furnishings, commercial grade appliances, and light fixtures.
Prime 7.96-acre commercial lot in Florence County, ideally situated just 1 mile from both McLeod Hospital and Florence Airport. This strategic location offers exceptional accessibility, making it a great opportunity for diverse commercial ventures just 5minutes from the growing Downtown Florence. Don't miss the chance to invest in this thriving area with proximity to key amenities and infrastructure.
COMMERCIAL possibility. Currently occupied as a home by owner. It is residential at the moment, but it has been commercial before according to seller. Located next door to a medical staffing business. Great Location. Sq. ft does not include the building in the rear of the property.
Great opportunity to buy a commercial property in the downtown area. APPOINTMENTS ONLY!
Super location, near Aldi and Wal-Mart on South Irby Street. 2019 Highway Department average traffic count 22,000 cars per day. Unit features 2,000 square feet, 2 bathrooms, separate office and extra space. Recently repaved parking lot, easily accessible with ingress and egress. Close to YMCA. This is a must see for a small business needing a good location. Huge apartment complex next door. Lots of traffic and excellent business location.
This is a 5000 square foot heated and cooled warehouse to be available October 1 2022. Formerly occupied by Mastec as a distribution center. Strategically located with frontage on I 95 at exit 167. This building has two roll up doors and a loading dock with a concrete paved fenced parking for 24 vehicles and one and a half acres for future expansion. Tenant is responsible for pro rata share taxes, utilities, and contents and liability insurance. $664 a month are the taxes. Base Rent is $3950 a month. There is 3.75 acres. Completely fenced lot. 3 phase electric service. Fully climate controlled building.
Excellent office location close to downtown Florence. Downstairs, has 3 private offices, conference room, receptionist office, lobby, kitchen and 2 bathrooms (one is private). Upstairs has skylights, 5 private offices, a lobby area plus another bathroom. The building has front and rear entrances. Paved parking for 14 cars. In addition, the building has 2481 square feet. 2 heat pumps. 604 South Coit Street is in the Office Professional District of Florence. The building is easily accessible from Irby Street, Cherokee Road or Palmetto Street. This building has been leased to Doctors, a Law Office and, most recently, a Home Health Care company. New roof on it in 2019. It is in great shape, inside and out and ready for occupancy. Front of building has 3 parking spaces. 11 parking spaces behind the building. Completely paved.
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The information being provided is for the consumer's personal, non-commercial use and may not be used for any purpose other than to identify prospective properties consumer may be interested in purchasing. Any information relating to real estate for sale referenced on this web site comes from the Internet Data Exchange (IDX) program of the Consolidated MLS®. This web site may reference real estate listing(s) held by a brokerage firm other than the broker and/or agent who owns this web site. The accuracy of all information, regardless of source, including but not limited to square footages and lot sizes, is deemed reliable but not guaranteed and should be personally verified through personal inspection by and/or with the appropriate professionals. Copyright © 2026, Consolidated MLS®.
Florence is located in South Carolina. Florence, South Carolina has a population of 39,816. Florence is more family-centric than the surrounding county with 27.93% of the households containing married families with children. The county average for households married with children is 26.6%.
The median household income in Florence, South Carolina is $52,425. The median household income for the surrounding county is $51,902 compared to the national median of $69,021. The median age of people living in Florence is 39.2 years.
The average high temperature in July is 91.7 degrees, with an average low temperature in January of 33.2 degrees. The average rainfall is approximately 45.2 inches per year, with 0.8 inches of snow per year.
