220 Hampton Avenue sits at the corner of Hampton Avenue and Johnson Street in the heart of Downtown Pickens. This property, once a private residence, is positioned within a district that allows for both residential and commercial use, giving future owners the flexibility to shape it into something meaningful. Whether restored as a charming home or adapted into a business space, the location sets the stage for countless possibilities. The surrounding neighborhood reflects the character of Pickens with tree-lined streets, sidewalks that encourage evening strolls, and a true sense of community. Life here is both connected and convenient, with local parks, the Doodle Trail, and gathering spaces close by. From this location, it is easy to enjoy the best of small-town living while staying connected to larger destinations. Liberty and Clemson are just minutes away, while Greenville and Easley provide additional shopping, dining, and cultural opportunities. Outdoor enthusiasts will appreciate being so close to Table Rock for hiking and Lake Keowee for boating, fishing, and lakeside recreation. 220 Hampton Avenue is more than a property, it is an opportunity to be part of a growing town while creating something new in a setting that blends tradition with progress.
Commercial property offered for sale at 101 Secona Road in Pickens, SC. Priced at $149,900, this property offers an affordable opportunity for an owner-user, retailer, service provider, or entrepreneur. Situated on approximately 0.146 acres and zoned GBD (General Business District), the property occupies a distinctive site surrounded by three roadways, providing excellent visibility and multiple sight lines. The building features storefront windows, an open customer area, flexible interior space, and a rear service/prep area. Existing improvements include a commercial-style multi-compartment sink and walk-in cooler, providing useful infrastructure for food-related, specialty retail, market, beverage, catering, or other commercial uses. On-site parking is limited. Prospective purchasers should independently verify zoning, permitted uses, utilities, equipment, parking requirements, and suitability for their intended use.
An exceptional opportunity in Pickens! This well-maintained facility is one of the nicest shelters you’ll find, offering a peaceful and convenient setting while remaining easily accessible to local amenities. The property has been thoughtfully cared for and provides ample space to serve a variety of community-focused uses. With a motivated seller and a property that shows pride of ownership throughout, this is a unique opportunity for an organization, nonprofit, or investor seeking a turnkey facility in a desirable location
An exceptional opportunity in Pickens! This well-maintained facility is one of the nicest shelters you’ll find, offering a peaceful and convenient setting while remaining easily accessible to local amenities. The property has been thoughtfully cared for and provides ample space to serve a variety of community-focused uses. With a motivated seller and a property that shows pride of ownership throughout, this is a unique opportunity for an organization, nonprofit, or investor seeking a turnkey facility in a desirable location
Fantastic building in a high traffic area. This location and building has a lot of potential for what it can be used for. It would e a great boutique shop, small office space, arts and crafts location. With the high volume of traffic passing by this building coming in and out of Pickens you basically have a massive billboard with this location to capture you business clientele. (The seller of this property is a licensed Real Estate Agent in South Carolina)
Be front and center! These two Main Street storefronts in Pickens are perfect for any small retail or service businesses. The third space is behind the two Main st locations facing Irwin Street and would be perfect for retail, service, or office space.
This is NOT your average listing. If you’ve been looking for something with flexibility, character, and opportunity—this is it. Located in the heart of Pickens, 155 Farrs Bridge Road offers a rare blend of residential comfort and commercial potential. Originally built in 1954, this 2-bedroom, 1.5-bath home sits on a .47-acre lot and is packed with possibilities. The home itself has that classic charm you’d expect, but what truly sets this property apart is the detached shop/garage space. With approximately 1,500 square feet plus an additional 600 square feet of covered area, this structure opens the door for a variety of uses—whether you’re thinking workshop, storage, hobby space, or even a small business setup with potential storefront visibility. Whether you’re an investor, entrepreneur, or someone looking for a live/work setup, this property gives you the freedom to create something unique. The lot provides ample space for parking, expansion, or outdoor use, making it ideal for both personal and business needs. Properties like this don’t come around often—especially with this kind of versatility and location. Bring your vision and make it your own.
Welcome to 149 April Valley Lane! A truly unique property located at the foot of Glassy Mountain between Pickens and Dacusville in the foothills of Upstate SC. Interested in an income producing investment? The current owners have operated April Valley RV Park on the property for many years. The park currently leases 19 RV spaces, with an additional 8 spaces that have utilities in place. There is ample acreage for expansion should the new owner want to pursue it with Pickens County. All spaces have power, water and septic hookups. There is a park lodge building with laundry and bathroom facilities, an adult game room, TV, etc. Financials can be provided to qualified buyers during due diligence. This land has it all! The tract is primarily wooded, with mature hardwood and pines. It features frontage and access from Jameson Road and has 1,300 feet of frontage on Glassy Mountain Church Road. There are two ponds, one 4 acres and one ½ acre that are stocked with fish. A large granite rock bald overlooks the back of the big pond, offering dramatic views and breathtaking sunrises! An excellent trail system offers vehicle access to the majority of the property. Potential recreational activities include hiking, fishing and hunting (deer, bear, wild turkey and small game), shooting or trail riding. Looking for a secluded rural residence or family compound? The tract features two homes in very good condition. One is a 3,370ft2 single level with 5 bedrooms and 4 baths and the other is 5,000ft 2 two-level home with a full finished basement. Either of these homes would be suitable for a primary residence, or they could be converted to short- or long-term rental properties to complement the RV park. If your dream is to build a new custom home instead, there are multiple potential homesites on the property suitable for a new build. The 180-acre parcel directly to the north across Glassy Mountain Road is under a conservation easement and will never be developed. The location is excellent. You can be in Pickens in less than 10 minutes and make it to downtown Greenville in 30 minutes! You can hike at Table Rock, Caesar’s Head or Jones Gap State Parks or put your boat in the water at Lake Keowee in less than 30 minutes! Clemson University is also close by and offers educational opportunities and exciting athletic events throughout the year. Hunter Farms strawberry farm is directly across Jameson Road, offering prepicked or you-pick berries in season. The owners will consider reasonable offers to subdivide that preserve the viability of the remaining property.
Welcome to 149 April Valley Lane! A truly unique property located at the foot of Glassy Mountain between Pickens and Dacusville in the foothills of Upstate SC. Interested in an income producing investment? The current owners have operated April Valley RV Park on the property for many years. The park currently leases 19 RV spaces, with an additional 8 spaces that have utilities in place. There is ample acreage for expansion should the new owner want to pursue it with Pickens County. All spaces have power, water and septic hookups. There is a park lodge building with laundry and bathroom facilities, an adult game room, TV, etc. Financials can be provided to qualified buyers during due diligence. This land has it all! The tract is primarily wooded, with mature hardwood and pines. It features frontage and access from Jameson Road and has 1,300 feet of frontage on Glassy Mountain Church Road. There are two ponds, one 4 acres and one ½ acre that are stocked with fish. A large granite rock bald overlooks the back of the big pond, offering dramatic views and breathtaking sunrises! An excellent trail system offers vehicle access to the majority of the property. Potential recreational activities include hiking, fishing and hunting (deer, bear, wild turkey and small game), shooting or trail riding. Looking for a secluded rural residence or family compound? The tract features two homes in very good condition. One is a 3,370ft2 single level with 5 bedrooms and 4 baths and the other is 5,000ft2 two-level home with a full finished basement. Either of these homes would be suitable for a primary residence, or they could be converted to short- or long-term rental properties to complement the RV park. If your dream is to build a new custom home instead, there are multiple potential homesites on the property suitable for a new build. The 180-acre parcel directly to the north across Glassy Mountain Road is under a conservation easement and will never be developed. The location is excellent. You can be in Pickens in less than 10 minutes and make it to downtown Greenville in 30 minutes! You can hike at Table Rock, Caesar’s Head or Jones Gap State Parks or put your boat in the water at Lake Keowee in less than 30 minutes! Clemson University is also close by and offers educational opportunities and exciting athletic events throughout the year. Hunter Farms strawberry farm is directly across Jameson Road, offering prepicked or you-pick berries in season. The owners will consider reasonable offers to subdivide that preserve the viability of the remaining property.
This beautiful piece of property is 3.25 acres. There are so many possibilities . You can tear down the house and build your brand new business from scratch. You could possibly build several duplexes or several homes with the county permission. OR....If you want to use the existing home, you can have your contractor tag along and see what your options are to build your commercial dream. There are several commercial properties nearby.....The YMCA is right across the street. Valvoline Instant Oil Change. Dentist and Doctor offices are nearby. Seller does not assume any responsibilities in obtaining permits with Pickens County to change the property from residential to commercial. Per Pickens County Planning and Development, the new owner will be responsible for obtaining said permits.


Pickens is located in South Carolina. Pickens, South Carolina has a population of 3,326. Pickens is more family-centric than the surrounding county with 33.82% of the households containing married families with children. The county average for households married with children is 30.75%.
The median household income in Pickens, South Carolina is $42,688. The median household income for the surrounding county is $53,188 compared to the national median of $69,021. The median age of people living in Pickens is 36.1 years.
The average high temperature in July is 88.4 degrees, with an average low temperature in January of 26.5 degrees. The average rainfall is approximately 59.8 inches per year, with 1.3 inches of snow per year.