A FRONT-ROW SEAT TO DOWNTOWN SENECA'S NEXT CHAPTER! Located at 218 E North 1st Street, one level 2,745 square foot brick "shell" building, this distinctive commercial property offers an exciting opportunity to bring a new vision to life in the heart of Downtown Seneca. Positioned alongside Harper's Plaza and just steps from Main Street, Seneca Performing Arts, Ram Cat Alley, local restaurants, shopping, Jazz On The Alley every Thursday April thru October and the Seneca Amphitheater, this property puts your business or investment in the middle of one of the area's most inviting downtown destinations. Featuring classic brick architecture, expansive storefront-style windows, and three exterior entrances, the single-level building offers a versatile layout with multiple possibilities. Its location beside Harper's Plaza creates a unique connection to the surrounding downtown atmosphere, with the plaza's landscaped courtyard, gathering areas, and colorful playground contributing to the character and appeal of the setting. The interior is currently in unfinished shell condition, providing an opportunity to customize the space around a specific business concept rather than working within an existing finished layout. Whether the vision involves a boutique retail destination, restaurant concept, professional offices, creative studio, gallery, or another innovative commercial venture, the property offers a starting point for a truly distinctive transformation, subject to applicable zoning, building codes, and required approvals. But the real story here is the location. Downtown Seneca continues to draw attention through its established businesses, public gathering spaces, entertainment destinations, and revitalization efforts. With Main Street just around the corner and Harper's Plaza immediately alongside the property, 218 E North 1st Street offers an opportunity to become part of that ongoing story. Public Parking across from Main Street Bring your ideas, bring your vision, and discover what this downtown property could become. Schedule your private showing today! Property is offered in unfinished condition. Buyer to independently verify square footage, boundaries, access rights, building systems, property condition, permitted uses, and all applicable renovation requirements & original year of building address. Short term rentals allowed.
Two levels. 6,900 square feet mixed usage. Two independent entrances. One exceptional opportunity in the heart of Downtown Seneca! Located at 233 Main Street, this distinctive red brick "shell" building commercial property combines historic architectural character with the flexibility to create something entirely new, third building down from the Seneca Performing Arts, across from the Amphitheater, just steps from Ram Cat Alley, downtown shopping and dining, Jazz On The Alley every Thursday April thru October. The main floor offers approximately 3,178 square feet of unfinished commercial space, featuring expansive Main Street storefront windows, exposed framing, and multiple entrances. Large rear-facing glass doors and windows overlook Harper's Plaza, connecting the property visually to an inviting downtown courtyard and gathering space. The second floor offers approximately 3,369 square feet, with its own independent entrance via an exterior staircase accessible from the alley beside the building. This spacious upper level features exposed wood framing, an open layout, abundant natural light, and exterior balconies overlooking Main Street and the surrounding downtown area. Both floors are currently in unfinished shell condition, offering a blank canvas for a customized commercial buildout. The separate entrances create intriguing possibilities for multiple businesses, professional offices, retail concepts, creative studios, or a combination of uses, subject to applicable zoning, building codes, and approvals. What truly sets this property apart is its location. Positioned alongside Harper's Plaza and surrounded by the energy of Downtown Seneca's restaurants, shops, entertainment, and ongoing revitalization, 233 Main Street offers an opportunity to become part of downtown's next chapter. Public Parking across the street. Buyers to verify everything of importance. Whether you're an entrepreneur looking to establish a flagship location or an investor seeking a distinctive downtown property, this is a space worth exploring. Schedule your private showing and discover what 233 Main Street could become! Square footage reflects approximate iGUIDE-reported areas, not a verified official building total. Buyer to independently verify measurements, property condition, permitted uses, and renovation requirements including year of building address. Short term rental allowed.
THREE DISTINCT COMMERCIAL SPACES. ONE EXCEPTIONAL DOWNTOWN SENECA LOCATION. Positioned along Main Street in the heart of downtown Seneca, 225 Main Street offers a rare opportunity to bring new life to a distinctive two-story commercial building surrounded by the energy, character, and continued revitalization of the city's historic downtown. The two story white and red brick "shell" building consists of 11,160 square foot mixed-use. Featuring a classic brick façade, expansive storefront windows, and three independently accessed commercial spaces, this property offers exceptional flexibility for an investor, entrepreneur, or business owner with a vision. The main level features two separate storefronts, each with its own Main Street entrance. Storefront 01 includes approximately 2,379 square feet plus an additional 499-square-foot area. Storefront 03 offers approximately 2,476 square feet with both Main Street frontage and a secondary rear entrance. Between the storefronts, a dedicated street-level entrance provides independent stair access to Upstairs 02, an expansive upper-level space with approximately 4,492 square feet plus a separately measured 441-square-foot stair and entry area. The interiors are currently unfinished, offering an opportunity to customize the spaces for a variety of potential commercial uses, subject to applicable zoning, permitting, and approvals. Exposed structural elements, generous open areas, and the building's distinctive architectural character provide an exciting foundation for future redevelopment. LOCATION IS WHERE THIS PROPERTY TRULY SHINES. Situated in downtown Seneca, the property at Harper's Plaza is located across from the downtown Amphitheater, two buildings down from the Seneca Performing Arts. Walk to Ram Cat Alley for local restaurants, shops, and community gathering spaces for Jazz On The Alley every Thursday from April thru October. This setting offers businesses the opportunity to become part of an established and evolving downtown destination. Whether your vision involves retail, professional offices, creative studios, restaurants, or a combination of complementary businesses, 225 Main Street offers the space, flexibility, and location to explore the possibilities. Three independent entrances. Two levels. One remarkable downtown opportunity. Public parking is across the street. Schedule your private tour and discover what 225 Main Street could become. All square footage figures are approximate individual areas reported by iGUIDE and should not be interpreted as a verified total building area. Buyer to independently verify measurements, property condition, building systems, permitted uses, and all information material to their intended use, including original year of building address. Short Term rentals allowed.
THREE BUILDINGS. TWO DOWNTOWN STREETS. ENDLESS POSSIBILITIES. An extraordinary opportunity to make your mark in the heart of Downtown Seneca! Offered together, the three adjoining "shell" buildings at 225 Main Street, 233 Main Street, and 218 E North 1st Street present a distinctive commercial investment and redevelopment opportunity combining classic downtown architecture, multiple independently accessed spaces, and a location surrounded by shopping, dining, entertainment, and community gathering destinations. Positioned along Main Street and East North 1st Street, these three adjoining properties offer the character of an established downtown setting with the flexibility to create something entirely new. Whether your vision includes boutique retail, restaurants, professional offices, creative studios, galleries, entertainment venues, or a combination of complementary businesses, this collection of properties offers tremendous potential for a thoughtfully planned commercial destination, subject to applicable approvals. 225 MAIN STREET — THREE DISTINCT COMMERCIAL SPACES: This impressive two-story brick building 11,160 SF features classic architectural detailing, prominent Main Street storefront windows, and three independently accessed commercial areas. Two separate street-level storefronts offer direct entrances from Main Street, while a dedicated third entrance provides stair access to the expansive upper floor. Each space is currently unfinished, allowing a future owner to develop individualized layouts and business concepts. Short term rental condos or apartments allowed on the upper level. 233 MAIN STREET — TWO LEVELS WITH INDEPENDENT ACCESS: Featuring an attractive 6,900 SF brick facade, large commercial windows, and covered upper-level balconies, this property offers two separately accessed commercial levels. The main floor provides Main Street exposure with additional rear entrances, while the upstairs level is accessed by an exterior staircase through the Harper's Plaza passageway. The upper floor features a spacious open layout with exposed framing, multiple windows, and balcony areas overlooking both Main Street and the courtyard. Short term rental condos or apartments allowed on the upper level 218 E NORTH 1ST STREET — COURTYARD-FACING COMMERCIAL OPPORTUNITY: This single-level 2,745 SF commercial building features three exterior entrances, substantial storefront-style glass, and a distinctive position along East North 1st Street and adjacent to Harper's Plaza. Its location alongside the landscaped courtyard, gathering spaces, and playground creates an appealing setting for a business concept that could complement the surrounding downtown activity. THE LOCATION IS THE REAL DIFFERENCE. Just steps from New Seneca Performing Arts, the Seneca Amphitheater, Ram Cat Alley established downtown restaurants, locally owned shops, and public gathering areas for Jazz On The Alley, these properties occupy a highly visible position within Downtown Seneca. The surrounding brick architecture, pedestrian-friendly streetscape, nearby public parking, and continued downtown improvements contribute to an environment where businesses can become part of the community's ongoing growth and revitalization. All three buildings are currently in unfinished commercial shell condition, offering a substantial blank canvas for renovation and redevelopment. The combination of multiple storefronts, independent entrances, upper-level spaces, two street addresses, and proximity to Harper's Plaza creates possibilities for a coordinated commercial project or multiple distinct business concepts. One downtown location. Three unique buildings. An opportunity to create something truly special. Whether you're an investor, developer, or entrepreneur looking to establish a lasting presence in Downtown Seneca, this combined offering deserves your attention. Schedule your private tour and explore the possibilities!
4.77 acres zoned General Commercial that adjoins the former Premier Car Wash and El Agave Restaurant. Acreage is level at the the parking lot area and has gradual slope up to the road frontage on Mountain View Drive and Short Street. The land has access from Jantzen Court that leads to Mountain View Drive. All utilities available sewer, water, electric, natural gas located with in the city limits of Seneca. Buyers to verify everything of importance. Close to shopping, dining, medical, close to everything !
Former John Deere commercial property positioned along the highly visible Bypass 123 corridor in Seneca. The approximately 7,500± SF structure sits on 1.44 acres and offers elevated highway frontage that creates excellent exposure for boats, RVs, vehicles, equipment, or other commercial displays. The existing structure has been reviewed by a licensed engineer, providing buyers with valuable information as they evaluate renovation or redevelopment opportunities. The property may also be eligible for South Carolina rehabilitation tax incentives, potentially helping offset qualifying improvement costs. Buyers should independently verify eligibility and available incentives. With its combination of highway visibility, commercial potential, and proximity to Lake Keowee and the surrounding recreational market, the property could be well suited for a boat or RV dealership, storage facility, service center, specialty retail operation, or other commercial use. The newly surveyed 1.44-acre tract provides a more focused commercial footprint while retaining the property's prominent Bypass 123 presence. Buyers should independently verify zoning, permitted uses, measurements, utilities, tax incentives, and all other information important to their intended use. Explore the possibilities at 298 Bypass 123 in Seneca.
.30 acres of level land with shade trees with 104 Ft. of Road Frontage, located next to Oconee Welding. Walking distance to the new down town Seneca 2000 seat Amphitheater that opened on June 19th. Buyers to verify everything of importance.
Position your business for success at Heritage Station, 1510 Blue Ridge Blvd, Suite 103 in Seneca, SC. This main level 1,815 sq. ft. professional commercial space combines a polished business setting, functional layout and convenient access located at the right corner of this Plaza facing Blue Ridge Blvd. The suite features a spacious reception and waiting area or showroom, three private offices- one formerly used as a large conference meeting room, two restrooms, a janitor’s closet room, room at the rear corner area for break area and generous hallway space that provides an easy flow throughout the property. A rear exit offers additional access and the potential for a convenient employee entrance, while ample on-site parking helps accommodate both clients and staff. The versatile layout is well suited for a variety of professional uses, including financial services, insurance, legal, medical-related, administrative, consulting, or other office-based businesses. Existing furnishings and select artwork may also convey, providing an opportunity for a buyer looking for a more turnkey setup. Suite 103 could also be used for retail in this 11 suite plaza. Also available for lease at $ 2,875 per month. Located along Blue Ridge Blvd near Bountyland Road and Keowee School Road, Heritage Station offers convenient access to Seneca, Walhalla, and surrounding Oconee County. Whether you're relocating an established business, expanding your operation, or purchasing commercial space instead of leasing, Suite 103 offers the location, professional appearance, and functional layout to make a strong impression from day one. Schedule your private showing and see what Heritage Station Suite 103 can offer your business. Formerly the Edward Jones Suite purchased at new construction.
Live, Work, or Invest in Seneca! Endless potential with this unique 2-lot package on South Walnut Street. Offering rare flexibility, tract 18 and 19 S.Walnut are perfect for a commercial business, a residential build, or the ultimate "live-work" setup. Build your primary residence on the 1.49 acre residential lot and your business storefront, studio, or workshop right next door on the .71 acre tract. Located just outside the high-density corridor but close enough to capture steady traffic, this location keeps you less than 5 minutes from downtown Seneca's retail/dining district and a short hop to Clemson University. High visibility, great road frontage, and access to local utilities make this an investor's dream. Buying both allows you to control your footprint. Tract 18 with 149 acres currently has power set up with water and two septic systems. Owner will not separate tracts. Tract 18 is currently zoned residential which tract 19 is zoned commercial. Buyer and buyer's agent to confirm rezoning availability of either tract if they desire to rezone.
Position your business for success in this move-in-ready 1,290 sq. ft. professional office suite located at 528 By Pass, Suite C. Thoughtfully designed for efficiency and client interaction, the space features five private offices, a welcoming reception area, an ADA-accessible restroom, and a convenient kitchenette. Elegant crown molding, neutral finishes, and abundant natural light create a polished and professional environment that is both inviting and productive. The flexible floor plan is well suited for a variety of professional uses, including medical, counseling, legal, insurance, accounting, administrative, and other office-based businesses. Conveniently located and professionally appointed, this versatile suite offers an exceptional opportunity to establish or expand your business in a space designed to support growth, productivity, and success. Owner financing terms available. Could also be for lease at $ 2200 per month.
Position your business for success in this move-in-ready 1,290 sq. ft. professional office suite located at 528 By Pass, Suite C. Thoughtfully designed for efficiency and client interaction, the space features 6 private offices, a welcoming reception area, an ADA-accessible restroom, and a convenient kitchenette. Elegant crown molding, neutral finishes, and abundant natural light create a polished and professional environment that is both inviting and productive. The flexible floor plan is well suited for a variety of professional uses, including medical, counseling, legal, insurance, accounting, administrative, and other office-based businesses. Conveniently located and professionally appointed, this versatile suite offers an exceptional opportunity to establish or expand your business in a space designed to support growth, productivity, and success.
No Restrictions ! No HOA ! Sewer available, sewer man hole located in front of the property, can tap on at Wells Highway across the highway at buyers expense. 2.36 acres of un-restricted acreage that backs up to Clemson University land and has 572.52 ft of Clemson Blvd road frontage. The property was previously leased at $ 7000 per month to KX Clemson Fraternity that installed a Golf Par Three 110 yard putting green at the rear right corner near the shade tress before reaching the flowing creek. The fenced in property with gated entrance has RV Boat storage with power and water, several RV hookup sites.There is a detached Garage, Work Shop with Storage storage that leads up the concrete drive to the 2400 SF white brick building with a 2 car attached garage with an additional 784 SF of unfinished basement space. The freshly painted interior has hardwood floors on the main level that features a kitchen with breakfast bar, dining area, great room, 3 bedrooms, two full bathrooms, laundry room with sink that leads to the garage. The basement features another bedroom, full bath, full kitchen, recreational room, and unfinished storage. Ideally located midway to Clemson from Seneca for a Commercial Business at a traffic light intersection. Close to Clemson University, shopping, dining, medical, recreational, Lake Keowee and Lake Hartwell, close to everything. Great location for Retail, Office, Medical, Apartments, Nursery. Buyers to verify everything of importance. No Zoning ! Live there and run a business ! Enough land to build several cottages to rent out !
Suite B has a1254 SF floor plan with an open floor plan, an office, kitchenette, bathroom, storage area. Enough space to convert to 5 additional offices. Property can also be used by the new owner for Retail space. Suite B is located in one of the best spots in Seneca with heavy traffic passing by on By Pass 123. Close to shopping, dining, medical, downtown Seneca, Lake Keowee Marina, Close to Everything ! Buyers to verify everything of importance including square footage. Owner financing terms available.
Great Opportunity to own an all brick/concrete building in the City of Seneca SC. Located on an busy road in a growing area of Western Upstate SC. The Building Already has 2 tenants in place who now occupy close to 8000 Sqft which leaves over 7000 sqft for another tenant or an owner occupy situation. The building is built like a warehouse with 16-foot ceilings and No-load bearing walls. Lots of options to bring in other tenants or self-occupy.
3.60 acres with 781.71 SF+/- road frontage at Clemson Blvd. and 480.75 SF+/- of road frontage at Wells Highway. Corner property at the traffic light and and sewer availability at Wells Highway across the road. There is a Clemson Blvd. drive way entrance that leads to the former Barber-Shop Building. Level, gentle slope down to the flowing creek that leads to the water fall shoals. Sod grass was being installed and sprinkled from a pump installed at the creek. The brick building has been up-fitted inside into an open shell 1600 SF on the main where new owner can design and the staircase leads 1600 SF in the lower level that has new block pillars, wood-burning brick fire place and walk out door. Close to Clemson University, Lake Keowee, Lake Hartwell, Close to everything ! Buyers to verify everything of importance !
BEST LOCATION IN DOWN TOWN SENECA ! Prime Downtown Seneca Commercial Opportunity – 124 & 118 N Townsville St OPPORTUNITY ZONE ! This exceptional dual-property, two store-fronts commercial building in the heart of downtown Seneca, SC offers high visibility 11,500 VPD and unparalleled foot traffic. The Ye Old Sandwich Shoppe Restaurant (124 N Townsville) has 3224 SF and the Ice Cream/Confections Shoppe with large banquet room for celebrations (118 N Townsville) has 2548 SF. Both spaces present a unique opportunity for an established business or investor. These buildings feature 5772 SF, Hydro-Top Roof, Solar Hot Water With Electric Backup, Three HVAC'S. Situated in a vibrant downtown location, this property is perfectly positioned to capitalize on the city’s exciting developments: the new 702-Seat Performance Arts Center being constructed a few feet away directly beside the buildings estimated opening December 2026 and a 2000 seat State-Of-The-Art amphitheater just one block away opened June 19th, 2026. These upcoming venues are expected to draw significant traffic, making this location a prime hotspot for dining, retail, and entertainment businesses. Enjoy the Jazz Fest with live entertainment every Thursday evening during the Spring, Summer, Fall featuring a block party with street dancing and out door dining ! Don’t miss your chance to own a highly visible, strategically located property in a growing downtown area with strong economic and cultural activity. Buildings can be offered separately. Ye Ole Sandwich Shoppe Restaurant 3224 SF at 124 N. Townville Street and the Ice Cream Store 2548 SF at 118 N. Townville Street. Owner financing terms available. Owner retired, both buildings are vacant.
Owner Financing Available!! Prime Downtown Seneca Commercial Opportunity 110 E N 1st Street Seneca, SC Position your business for success in the heart of thriving downtown Seneca. This versatile commercial property offers 5,000 sq ft total — with 2,500 sq ft on the main level and an additional 2,500 sq ft upstairs — providing ample room for retail, office, dining, or mixed-use concepts. Enjoy unbeatable walkability with steady foot traffic, nearby shops, restaurants, and community events right outside your door. The prominent street-front location ensures high visibility and easy access for customers. Whether you’re an investor seeking rental potential or an entrepreneur ready to bring your vision to life, this property offers the space, location, and flexibility to make it happen. KEY FEATURES: Approx 5,000 sq ft total (2,500 sq ft per floor) Prime downtown Seneca address High-visibility storefront Walkable to dining, shopping, and events Endless potential for retail, office, or mixed-use This is your chance to own a cornerstone property in one of the Upstate’s most exciting downtown districts.
3.94 acres of commercial land only where month to month tenants are renting the land at W & W Housing Center and J & J Monument. No restrictions. 609.40 ft. of road frontage. Public Sewer can be applied for, Natural Gas at the Highway
.84 acre lot across from Harbor Freight and the Viking Boat Dealership. Premium location for a Plaza Building, Restaurant, Retail, Office. The property is also offered as two adjoining lots for sale at $ 985M for 1.45 acres or as a Ground Lease Opportunity. The DOT R/W road frontage has been purchased down to US BY Pass Highway 123. Buyers to verify everything of importance. Great location with highest traffic in Seneca, close to everything !
Total 4.67 acres with 2.74 Acres at 99 Northampton Road zoned Highway Commercial over looking US By Pass 123. The paved parking lot has 3 entrances. A 1500 SF brick building viewing By Pass 123 traffic is ideal for advertising signage facing the traffic. Environmental Phase 1 completed for a clean site.The property was most recently occupied by Builders Source for their lumber-building materials prior to building a new store. The former developer/owner designed a site plan with 4 Hilltop office buildings. The adjoining 1.93 acres is located off Hill Top Drive. If a smaller parcel lot is needed, acreage also offered at $ 500,000 per acre and higher based on lot lines and parcel size. Perfect spot for a retail new tire store, restaurant, and much more ! Buyers to verify everything of importance. Close to Lake Keowee, downtown, shopping, dining, medical, Clemson, close to everything !
4.3 acres located at 1018 E. North 1st Street, across from the QT-Quik Trip and the Hampton Inn, with visibility from US By Pass Highway 123, the acreage is next to the Shine On Seneca Car Wash with high traffic volune from By Pass 123. The entire acreage is listed at $ 3.5M. Also available at $ 750,000 per acre and higher based on lot lines and parcel size. The acreage is level with two curb cuts for access from E. North 1st Street and also has access from West Clemson Street to US By Pass 123. Environmental Phase 1 completed for a clean site. Perfect spot for a retail new tire store, restaurant, extended stay hotel, great location for everything leading to the Gate Way of Down Town Seneca. Buyers to verify everything of importance. Located within the City Limits of Seneca, walking distance to Ingles, CVS, Publix, close to shopping, dining, medical, Lake Keowee Marina, minutes from Clemson University.
Corner level lot with shade trees at E. North 1st Street 1.29 acres located at the Gate Way to down town City of Seneca. 196 ft of road frontage, all utilities on site. Phase 1 Environmental completed by Goldie and Associates for a clean site. Close to town, shopping, dining, Ram Cat Alley. Minutes from Lake Keowee and Clemson University ! Buyer to verify everything of importance !
Attention Commercial Property Investors or someone looking for a great business location! Just outside Seneca city limits on busy Radio Station Rd with great road frontage! This was the original Radio Station - the towers behind the building are NOT ON THE PROPERTY! Remodel existing building or tear down and build new. This property is FULL of potential!
76.66 acres with in the city limits of Seneca with all utilities available. The 31.66 acres that fronts the Frontage Road and Blue Ridge Blvd is Tax Map Number 520-80-01-002. Tax Map Number 520-80-01-001 45+/- acres is being surveyed for exact acreage located off of Knollwood Drive. New owner can apply for zoning with the city of Seneca for single family, multi-family, mixed commercial, commercial, etc., this Crescent land has never been zoned. The Lake Keowee interior acreage is close to town, shopping, dining, medical, Clemson University. Buyers to verify everything of importance.
45+/- acres Lake Keowee interior acreage with in the city limits of Seneca with all utilities available. A new survey has been ordered for exact acreage. New owner can apply for single family, multi-family, mixed commercial, commercial, etc. zoning with the city of Seneca, this Crescent land has never been zoned. Close to town, shopping, dining, medical, Clemson University. Buyers to verify everything of importance.


Seneca is located in South Carolina. Seneca, South Carolina has a population of 8,734. Seneca is less family-centric than the surrounding county with 21.33% of the households containing married families with children. The county average for households married with children is 21.71%.
The median household income in Seneca, South Carolina is $48,816. The median household income for the surrounding county is $52,842 compared to the national median of $69,021. The median age of people living in Seneca is 39.6 years.
The average high temperature in July is 90.2 degrees, with an average low temperature in January of 31.1 degrees. The average rainfall is approximately 53.4 inches per year, with 2.3 inches of snow per year.