THREE MONTHS FREE RENT WITH 3-YEAR LEASE! Excellent high traffic office location right on 3rd St! Unit features 1-2 office spaces. Fantastic building with tons of amenities including parking, bathrooms on each level, elevator and beautiful vaulted main level common area. Right off the main drag and barley North of downtown La Crosse. Exterior signage opportunity also available! $19/sq ft. All utilities included!
Discover a rare downtown La Crosse opportunity at 422-424 Main St. Formerly ''The Main'' event venue, this property blends historic character with modern versatility--featuring a large stage, lighting, bar, kitchen equipment, and a corner office suite. The expansive lower level offers ideal storage or additional build-out potential. The upper level at 424 Main is a luxury apartment currently used as a short-term rental, providing proven income. Keep the event use or reimagine the space for your vision--steps from restaurants, nightlife, and the riverfront. A flexible commercial property in the heart of downtown energy. All equipment is negotiable for a seamless transition. We'll help you shape the vision.
Highly visible building at the intersection of Cameron Street and 4th Street South. High traffic counts, convenient parking lot located at the back of the building. Existing layout could be built-out easily to fit many needs. Breakroom, 2 bathrooms, basement storage. Rent rate 2500/month with 36 month lease term. In addition to base rent, utilities are the responsibility of the tenant. Additional lease terms to be negotiated based on the length of lease.
Excellent commercial / retail space on busy Mormon Coulee Rd. Many updates both inside and out. Front, retail space is 80'x40' and the additional rear, shop space is 21' x 60' and has a current month to month sub lease tenant. Rear space also has abundant fenced in and gated storage. Total 4,460 sq ft. Triple net lease. Please schedule showings. Two tenant building.
THREE MONTHS FREE RENT WITH THREE YEAR LEASE! Don't miss out on this opportunity to move your business to the desirable downtown area! Formerly an MMA gym, this space is just under 3,500 sq. ft. of divisible, customizable business or work shop space right on Main St. in downtown La Crosse. Perfect for an art gallery, showroom, MMA gym, climate-controlled storage, speakeasy, etc! Space has a street level private entrance for your business advertising. Private bath and kitchenette. $1,588/mo and $300/mo monthly CAM. Lease term negotiable. Brand new forced air heating and cooling system.
YOUR BUSINESS WILL NOT GET MISSED ON THIS HIGH PROFILE 3/4 ACRE (+/-) DOWNTOWN CORNER IN THRIVING LA CROSSE BUSINESS DISTRICT! PLENTY OF DRIVE BY TRAFFIC/VISIBILITY, CONVENIENT LOCATION FOR CUSTOMERS, EASY ACCESS TO INTERSTATE/COMMERCE HUB, PLENTY OF PARKING/BUILDABLE SPACE. THERE IS AN EXISTING FUNCTIONAL 5000 SF BRICK BUILDING ON THE .71 ACRE SITE. BUILD OUT TO SUIT YOU AND YOUR VALUED CUSTOMERS NEEDS! SUPER LOCATION; LOCATED AT THE BASE OF THE MISSISSIPPI BRIDGE FROM WEST TO GREET YOUR MINNESOTA CLIENTS & EASY ACCESS FOR YOUR COULEE REGION CLIENTS. BRING YOUR IDEAS, YOU CAN NOT FIND ACREAGE OF THIS SIZE IN A LOCATION LIKE THIS!
THREE MONTHS FREE RENT WITH 3-YEAR LEASE! Excellent high traffic office location right on 3rd St! This space offers 4 private offices, a kitchenette, and a flexible use room.A fantastic building with tons of amenities including parking, bathrooms on each level, elevator and beautiful vaulted main level common area. Right off the main drag and barley North of downtown La Crosse. Exterior signage opportunity also available! $19.95/sq ft. All utilities included!
Prime ''A'' location with exceptional visibility! Owner retiring and ready to pass along this well-maintained 10,300 sq ft property featuring updated lighting and durable standing-seam steel roofs on both buildings. Ideal for investors or business owners seeking a high-traffic site with direct exposure on one of the area's busiest highways. Seller may also offer the PM Sleep Center business and inventory (not included in sale price) and provide transition training. Longstanding reputation built on quality products and exceptional service. Don't miss this rare, high-visibility opportunity!
Modern, tastefully updated former salon and wellness space in the heart of downtown La Crosse! With 4,092 sq ft across the main and partial upper level, this property is ideal for a salon, aesthetics, or health/wellness business. Features include 9 off-street parking spots, front and back entrances, and a prime location surrounded by thriving downtown energy. Current tenant moving out by end of year. $12/sq ft. and $3.63/sq ft CAM. Tenant responsible for in-unit utilities. 3-5 year lease minimum.
Versatile 13,700 sq ft building featuring office space, ample storage, private offices, conference rooms, and open floor areas--ideal for a gym, warehouse, or light industrial use. Located in a thriving business park with convenient access and plenty of parking. Perfect turnkey setup for businesses needing a mix of office and operational space. Truck doors and loading dock with additional cold storage. Gross Lease $7,000/month.
Nearly 11,000 sq ft of mixed use, versatile and impeccably kept multi-use building is now on the market! This property features two office spaces off of 16th St loaded with high end custom cabinetry, multiple office spaces, reception area, tons of space and even a built-in safe! Massive heated warehouse space with a plethora of overhead doors, perfect for storage or a whole other separate tenants space from the two offices. Warehouse space can be rented to multiple different tenants or used for one. And to top it off, a 2,400 sq ft high-end upper level apartment! Custom cabinetry, hardwood floors, rec area and 4BRs! This unique property has everything you need for a business owner occupy, or fantastic investment property!
For Lease - 1,200 sq ft Commercial Shop on French Island! This clean, versatile space features in-floor heat included in rent for year-round comfort and efficiency. With 200-amp electrical service, it's ideal for trades, storage, or small business operations. Office and restroom connected directly to the shop. Centrally located on French Island with quick access to La Crosse and Onalaska. Vacant and ready for immediate move-in!
This highly visible commercial space is available for sale or lease. The former Pizza Hut restaurant space has kitchen, commercial refrigerator, hood, and large furnished dining area. Large lot with plenty of parking. Nearly 24,000 vehicles travel by this location daily. About 3/4 mile from Interstate 90.
This well-maintained, large commercial property offers exceptional versatility with a combination of shop and office space, ideal for a variety of business needs. Spacious Shop area with 14 oversized overhead doors, including drive-thru doors, providing easy access for large vehicles and equipment. Tree-Phase Power: Ample power supply for heavy-duty machinery and equipment, ideal for industrial or manufacturing operations. Additional storage/shop building: separate building on-site offering more space for separate storage, workshop or specialized operations. Approx. 21,000+/- SF shop area, 1,700 +/- office area, 7500 SF out-building. Property includes parcels 17-20248-60, & 17-20248-070. Listed tax amounts are combined parcels.
THREE MONTHS FREE RENT WITH 3-YEAR LEASE!Prime downtown location! This commercial space features beautiful hardwood floors, abundant natural light, and a versatile layout. Situated in the heart of downtown, it offers easy access to shops, restaurants, and local amenities. Perfect for a retail business, boutique, or spacious office, this property combines character with convenience in a highly desirable setting. Option to combine with large one-room vacant space also. $13/sq ft. $1,209/mo lease. $142/mo in CAM charges. Adjoining space of 277 sq ft that you can combine with also for a total of 1,393sq ft.
Landlord offering 3 months of free rent with a 3-year lease! Quiet 2nd-floor office space available in the 513 Main building in downtown La Crosse. This one-room office offers a simple, efficient layout ideal for focused work or a small business setup. Located in the heart of downtown, you'll enjoy easy access to restaurants, shops, and local services, with public transportation just steps away. A great opportunity for those seeking a convenient, professional workspace in a central location. $13/sq ft. $300/mo lease. $40/mo in CAM charges. Adjoining space of 1,116 sq ft that you can combine with also for a total of 1,393sq ft. Utilities included!
A commercial location with visibility to 34,000 vehicles per day!! The light industrial zoning offers the possibility for many businesses in the space. The current clinic has several exam rooms and work spaces that would be ideal for office spaces and conference rooms. The property has a residential apartment on the upper level as well as garage parking and large paved lot for customers and employees. Take advantage of this highly visible convenient location for your business.
Professional office space 1550 sq ft triple net lease is $14.50 plus cam per sq ft.Office with a view overlooking the marsh next to Trees Today garden shop. Visible space and signage on Hwy 16 just south of controlled intersection.
Great opportunity to own an established bar. Spacious horseshoe bar with multiple high-top tables for seating. Additional room that has 2 pool tables and gaming machines. Options for pool and dart leagues and enough space to have bands play. Bring additional income with the separate 3-bedroom rental home. Which offers main floor laundry and separate utilities including water. Some off-street parking. All basic bar equipment included.
THREE MONTHS FREE RENT WITH 3-YEAR LEASE! Excellent high traffic office location right on 3rd St! Unit features 6 private offices and numerous shared office spaces. Fantastic building with tons of amenities including parking, bathrooms on each level, elevator and beautiful vaulted main level common area. Right off the main drag and barley North of downtown La Crosse. Exterior signage opportunity also available! $19.95/sq ft. All utilities included!
Position your business for success with this high-visibility, high-traffic, street-level commercial space located on Main St in downtown La Crosse. Offering approximately 900 sq ft, this space features a spacious main area, private office and/or conference room and a storage area. Whether you are a solopreneur looking for a space of your own or have a small team and want to establish your presence downtown La Crosse, this space might be for you.
THREE MONTHS FREE RENT WITH 3-YEAR LEASE! Updated and professional 4,800 sqft on the 1st floor right next to bathrooms. 8 private offices, break room, reception and cubicles. $9.95/sq ft. Tenant pays electric, no other utility charges, no CAM charges. Limited parking available.
Professional Office Space Available on State Road 16!Strategically positioned with visibility to over 34,000 vehicles daily, this 2,500 sq ft main floor office offers nine private offices and generous storage for $3,500/month. An optional 3-bedroom apartment above may be leased by the main floor tenant for $1,500/month--ideal for live-work arrangements. Exceptional signage and exposure enhance this location's potential for office, retail, workshop, or storage use. Cold storage is available in a 64'x64' pole shed with concrete flooring and power. Entire shed: $3,500/month; Partial units: 42'x64' ($1,500), 21'x64' ($1,000). Owner is open to leasing any combination of office space layouts. Contact agent for options available.
For Sale or Lease. Professional Office Building located on the South side of La Crosse. Renovations and additions took place in 1994 and 2006, two separate entrances allowing for an additional tenant. Two stories offering conference rooms and open work areas with multiple private offices. Constructed of pre cast and steel, built to last. Close to Shopping Centers, and a variety of Restaurants, Coffee Shops and Public Park. 9-13 per SF Lease rate depending on Owner TI input and length of term.
| Information is supplied by seller and other third parties and has not been verified. This IDX information is provided exclusively for consumers personal, non-commercial use and may not be used for any purpose other than to identify perspective properties consumers may be interested in purchasing. Copyright 2026 - Wisconsin Real Estate Exchange. All Rights Reserved Information is deemed reliable but is not guaranteed |
La Crosse is located in Wisconsin. La Crosse, Wisconsin has a population of 52,505. La Crosse is less family-centric than the surrounding county with 27.08% of the households containing married families with children. The county average for households married with children is 30.96%.
The median household income in La Crosse, Wisconsin is $47,067. The median household income for the surrounding county is $62,817 compared to the national median of $69,021. The median age of people living in La Crosse is 29.4 years.
The average high temperature in July is 83.5 degrees, with an average low temperature in January of 9.2 degrees. The average rainfall is approximately 33.5 inches per year, with 41.4 inches of snow per year.