Rare opportunity along Sea Island Parkway featuring multiple parcels with flexible zoning and high visibility. The front parcel, DMP front, is zoned T2 Rural Center (T2RC), supporting mixed-use development including retail, office, residential, and limited light industrial. The rear parcels, DMP rear one and DMP rear two, are zoned T2 Rural (T2R), preserving open-space and agricultural character while allowing low-density residential, farming, and accessory structures. A house is on the front parcel but has no value and is included only with the land. The property offers a unique combination of visibility on Highway Twenty-One with quiet rear acreage for privacy, agriculture, or expansion. Public water is available via BJWSA; buyer and agent to verify availability, connection, and capa
Take advantage of this chance to own a property in a prime location on Saint Helena Island. The property spans a full acre and boasts approximately 90 feet of frontage on Sea Island Parkway - Rt. 21. It features a paved driveway and a parking lot that can accommodate around 10-14 cars, with potential for expansion. Currently, the property is being used as an attorney's office, which includes five rooms, a kitchen, a bathroom, and handicap parking with a ramp. Thanks to its flexible zoning classification, the property can be adapted for various professional occupations, or even repurposed into a storage facility with some creative thinking.
Discover a hidden gem along Highway 21 with this versatile property on Harbor Island. Situated on a half-acre parcel with prime Hwy-21 frontage, the site includes a three-story 3,520 SF building, a 1,000 SF utility shed, and a paved parking lot. Occupied by Tidewatch Vacation Rentals since 2018, the building is in good condition and features a flexible layout with storage and laundry in the basement, offices on the upper floors, and a full bathroom—creating opportunities for office, live-work, residential, or short-term rental use. With its proximity to Fripp Island, Harbor Island, and Dataw Island, this location offers guaranteed exposure to resort and gated community traffic. The property boasts gorgeous Lowcountry water and marsh views on one of SC's coveted barrier islands.
Welcome to 2123 Sea Island Parkway - an amazing commercial real estate opportunity on the beautiful Harbor Island! Conveniently located just 5 miles from Fripp Island and under a mile from Hunting Island, this prime property sits directly off the busy Sea Island Parkway, providing excellent visibility and easy access for clients and employees. With ample parking available, the building is designed to accommodate both visitors and staff. The basement is currently occupied by a vacation rental business, with their own designated entrance and exit to the building. Please note that no other vacation rental businesses will be allowed to occupy the building.
Nicely nestled in the heart of St. Helena, this commercial property has been fixed up from top to bottom. New metal roof, flooring, paint, updated bathrooms, outdoor covered porch and more! Currently occupied with a growing, successful restaurant. Acreage out back has endless possibilities for growth and development. Currently zoned C4 Community Center Mixed Use.
This property, spanning 1.7 acres with over 450 ft of highway frontage on St. Helena Island, is zoned Rural T2R and ideal for light commercial use. With a boat ramp just 0.3 miles away, quick access to lowcountry waters is a notable advantage. Additionally, it is less than 5 miles from Hunting Island and the beach, and Historic Downtown Beaufort is within a 20-minute drive. The sale includes two parcels (R300.013.000.057A0000 and R300.013.000.05980000), a well, and power connections. Please note that the storage building is being sold as is.

Andrea Conner, License 102111, Xome Inc., License 19633, [email protected], 844-400-9663, 750 State Highway 121 Bypass, Suite 100, Lewisville, TX 75067

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St Helena Island is located in South Carolina. St Helena Island, South Carolina has a population of 11,104. St Helena Island is less family-centric than the surrounding county with 13.82% of the households containing married families with children. The county average for households married with children is 21.25%.
The median household income in St Helena Island, South Carolina is $64,215. The median household income for the surrounding county is $74,199 compared to the national median of $69,021. The median age of people living in St Helena Island is 53.5 years.
The average high temperature in July is 91.1 degrees, with an average low temperature in January of 39.2 degrees. The average rainfall is approximately 47.8 inches per year, with 0.1 inches of snow per year.