Opportunity is knocking on this long-standing small-town clinic located right on a main highway with excellent visibility and easy access. For many years this nearly 4,000 square foot building has served the community as a medical office and is now ready for its next chapter. The layout is functional and spacious, featuring a welcoming front lobby, reception/front office area, three private professional offices, approximately ten 10x10 exam rooms, a dedicated lab room, dark room, X-ray room with lead walls, five bathrooms, and multiple storage rooms throughout. The existing floorplan makes it easy to continue as a doctor’s office, dental practice, specialty clinic, chiropractic office, physical therapy center, counseling center, or outpatient care facility. Beyond medical use, the space offers incredible flexibility. With numerous private rooms and bathrooms, it could convert to a daycare, learning center, tutoring facility, co-working space, business suites, wellness spa, beauty academy, church offices, nonprofit headquarters, or even office space for oilfield, construction, or agricultural operations. The solid layout provides a head start for many different business models. Situated on a main highway, the property offers strong drive-by traffic and convenience, with parking available both in the front and rear of the building. While the building does need some work and updating, it presents a fantastic opportunity for an owner-user or investor to renovate and customize it to fit their vision. If you’ve been looking for a large commercial space with great bones, high visibility, and endless potential in a small-town setting, this could be the one.
High Visibility Location!! Well-suited for medical, dental, salon, or other professional office uses. This 2,406 sq ft corner-lot property on W. Grand Avenue previously operated as a dental office. It offers a functional, clinic-ready layout. The building includes five exam rooms that could be used as offices, a reception/waiting area, a 6th private office with its own private bathroom, and a designated visitor restroom. Wood flooring adds warmth throughout much of the space. A metal standing-seam roof installed in 2000 and two HVAC systems provide for year-round comfort. A detached two-car garage behind the building provides additional storage or parking. The adjacent lot at 503 W Grand Avenue is included, providing extra frontage, a handicap parking space, and wheelchair ramp access. Additional street parking is available. This property presents an excellent opportunity in this high-visibility location.
Step into a remarkable piece of Yoakum history with this iconic commercial property—the original Yoakum National Bank building, built in 1894 and proudly recognized with a historical marker. Spanning over 8,000 sq ft, this landmark has been over 50% rehabbed, including new plumbing, updated electrical, and a 20-year roof, offering peace of mind while preserving its timeless character. The property is already income producing, with most of the downstairs currently leased and two beautifully finished upstairs apartments also leased, providing immediate cash flow for a new owner. The main level features marble floors and accents, a kitchenette, two half baths, a bar, and five original walk-in vaults—a rare and unforgettable feature that highlights the building’s rich banking history. The open layout and high ceilings make the downstairs ideal for offices, retail, boutique storefronts, a tasting room, or an entertainment venue. Upstairs is walk-up only with both front and rear stair access and showcases tall windows that flood the apartments with natural light, creating an inviting residential or studio atmosphere. Located on W. Grand Avenue in downtown Yoakum, this property enjoys excellent visibility, walkability, and proximity to local shops and restaurants. Centrally located less than two hours from Austin, San Antonio, Houston, and Corpus Christi, it offers strong appeal for regional business and tourism. Owner financing is available, making this a rare opportunity to own a historically significant, partially rehabbed, income-producing property in one of Texas’s most charming small towns.
Looking for a proven business opportunity? This well-established bar sits on 1.77 acres and offers exceptional visibility, ample parking, and a fully furnished, turn-key setup. Currently operating successfully, this property includes all equipment, tables, furnishings, and bar essentials—making for a seamless transition for the next owner. Inside, you’ll find a spacious layout designed for efficiency and customer flow. Outside features include a large back patio perfect for events or additional seating, as well as extra covered storage behind the building for equipment, inventory, or expansion needs. Whether you're expanding your portfolio or stepping into business ownership, this property delivers an incredible opportunity with room to grow.
This rare 0.24-acre corner parcel in Yoakum, Texas, offers exceptional dual frontage on US Highway 77A and W. Grand/Hwy 111, positioning it within a high-traffic corridor that sees an estimated 11,400 vehicles daily. The lot includes a small office building (approximately 468 sq ft) and ample space for customer parking, making it ideally suited for a food-truck site, café, coffee shop, professional or retail office, drive-through operation, or flexible pop-up retail.
This 2-acre property is ready to generate income with 14 RV hookups, each serviced by a septic and water well system designed to meet the needs of every slot. A 2-bedroom, 2-bath mobile home offers updated comfort with new flooring and a new roof, perfect for on-site management or additional rental income. A storage shed adds convenience, while frontage on both a county road and a farm-to-market road ensures easy access. Located just minutes from Yoakum and less than 30 minutes to Hallettsville, Cuero, Shiner, and Moulton—and under 45 minutes to Gonzales, Victoria, and Edna—this property is ideally positioned for the rising demand from oil and gas activity in the area. Whether you're looking to expand your investment portfolio or step into a high-demand rental market, this setup is ready to work for you.
Turnkey Opportunity: Veterinary Clinic for Sale in Yoakum, Texas — A High-Demand, Zero-Competition Market Step into a rare and lucrative opportunity in the heart of Yoakum, Texas. This veterinary clinic offers immediate access to an underserved market with no existing veterinary provider within city limits. With a population of ~6,000 and more than 1,700 pet-owning households, Yoakum represents a uniquely strong demand base for a new or expanding veterinarian. Residents currently travel to surrounding towns for even basic pet care, creating a built-in client pipeline for a local clinic. Based on Texas pet-ownership rates and national spending averages, Yoakum’s pet owners generate an estimated $550,000–$650,000 in annual veterinary spending—the majority of which is currently leaving the community. This clinic is ideally positioned for a veterinarian seeking: - Immediate patient volume - Strong recurring revenue from wellness care - Growth potential in small-animal, large-animal, and mixed-animal services - A loyal, relationship-driven client base - A strategic location drawing from Yoakum, Sweet Home, Hochheim, Shiner outskirts, and rural ranching communities Whether you’re launching your first practice or expanding your footprint, this is a rare chance to own the only veterinary clinic in a thriving Texas community. The demand is here. The market is open. The opportunity is exceptional.
Original Circle Y Building offices, This is a 1.5 story building with space upstairs.Opportunities are endless. Has existing offices and restrooms. Use your imagination in this building with a rich history.
Conveniently situated just off US Highway 77, offers superb visibility and accessibility, making it an excellent choice for your new business venture. The location is surrounded by hotels and shopping areas, ensuring a steady flow of potential customers. Spanning approximately 0.40 acres, this versatile lot is full of potential and can accommodate various types of businesses. Whether you're considering launching a retail store to cater to the local community, establishing office spaces for professionals, creating a medical facility to serve nearby residents, or opening a family restaurant that invites people to gather and enjoy, this property is equipped to meet your needs. With its proximity to town, you can capitalize on both foot traffic and drive-by visibility. Don’t miss out on this opportunity to bring your vision to life! Schedule your showing today and start planning your future success in this incredible location!
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| This information is provided by the Central Texas Multiple Listing Service, Inc., and is deemed to be reliable but is not guaranteed. IDX information is provided exclusively for consumers’ personal, non-commercial use, that it may not be used for any purpose other than to identify prospective properties consumers may be interested in purchasing. Copyright 2026 Four Rivers Association of Realtors/Central Texas MLS. All rights reserved. |
Yoakum is located in Texas. Yoakum, Texas has a population of 5,815. Yoakum is more family-centric than the surrounding county with 37.71% of the households containing married families with children. The county average for households married with children is 29.04%.
The median household income in Yoakum, Texas is $42,882. The median household income for the surrounding county is $57,602 compared to the national median of $69,021. The median age of people living in Yoakum is 35.7 years.
The average high temperature in July is 93.9 degrees, with an average low temperature in January of 40.5 degrees. The average rainfall is approximately 39.7 inches per year, with 0 inches of snow per year.
